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Effect of processed and fermented soyabeans on net absorption in enterotoxigenic Escherichia coli-infected piglet small intestine

Published online by Cambridge University Press:  08 March 2007

Jeroen L. Kiers ,
M.J. Robert Nout ,
Frans M. Rombouts ,
Esther E. van Andel ,
Marius J.A. Nabuurs  and
Jan van der Meulen
Jeroen L. Kiers
Affiliation:
Agrotechnology and Food Sciences Group of Wageningen URLaboratory of Food MicrobiologyPO Box 81296700 EV WageningenThe Netherlands Animal Sciences Group of Wageningen URAnimal Resources DevelopmentPO Box 658200 AB LelystadThe Netherlands Friesland Foods Western EuropePO Box 1596710 BD EdeThe Netherlands
M.J. Robert Nout
Affiliation:
Agrotechnology and Food Sciences Group of Wageningen URLaboratory of Food MicrobiologyPO Box 81296700 EV WageningenThe Netherlands
Frans M. Rombouts
Affiliation:
Agrotechnology and Food Sciences Group of Wageningen URLaboratory of Food MicrobiologyPO Box 81296700 EV WageningenThe Netherlands
Esther E. van Andel
Affiliation:
Animal Sciences Group of Wageningen URAnimal Resources DevelopmentPO Box 658200 AB LelystadThe Netherlands
Marius J.A. Nabuurs
Affiliation:
Animal Sciences Group of Wageningen URAnimal Resources DevelopmentPO Box 658200 AB LelystadThe Netherlands
Jan van der Meulen*
Affiliation:
Animal Sciences Group of Wageningen URAnimal Resources DevelopmentPO Box 658200 AB LelystadThe Netherlands
*
*Corresponding author: Dr Jan van der Meulen, fax +31 320 238050, email [email protected]
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Abstract

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Infectious diarrhoea is a major problem in both children and piglets. Infection of enterotoxigenic Escherichia coli (ETEC) results in fluid secretion and electrolyte losses in the small intestine. In the present study the effect of processed and fermented soyabean products on net absorption during ETEC infection was investigated. Soyabean was processed into an autoclaved, a cooked and a mould-fermented (tempeh) product. The soyabean products were pre-digested and the effect of the products on net absorption in the small intestineof piglets was studied. Pairs of small-intestinal segments, one non-infected and the other ETEC-infected, were perfused simultaneously with the different products during 8h. Net absorption of fluid, DM, Na, chloride, K and total solutes was determined. Net fluid absorption washighest for cooked soyabean followed by autoclaved soyabean and tempeh as a result of the osmolality of these products. In ETEC-infected segments, cooked soyabean and tempeh showed minor fluid losses (27 (se 23) and 43 (se 20) μl/cm2, respectively) compared with the saline control (260 (se 23) μl/cm2). Tempeh resulted in a high uptake of solutes. Processed soyabean products, particularly cooked soyabean and tempeh, are beneficial in maintaining fluid balance during ETEC infection. Additionally, tempeh showed high DM and total solute absorption. Therefore, particularly, tempeh may bebeneficial in the case of post-weaning diarrhoeain piglets and possibly in children as well.

Keywords

SoyabeansEnterotoxigenic Escherichia coliAbsorptionPigsDiarrhoea
Type
Research Article
Information
British Journal of Nutrition , Volume 95 , Issue 6 , June 2006 , pp. 1193 - 1198
Copyright
Copyright © The Nutrition Society 2006

References

Bhan, MKCurrent and future management of childhood diarrhoea. Int J Antimicrob Agents 2000 14, 71–73.CrossRefGoogle ScholarPubMed
Chandler, DS & Mynott, TLBromelain protects piglets from diarrhoea caused by oral challenge with K88 positive enterotoxigenic Escherichia coli. Gut 1998 43, 196–202.CrossRefGoogle ScholarPubMed
Ehrlein, H, Haas-Deppe, B & Weber, EThe sodium concentration of enteral diets does not influence absorption of nutrients but induces intestinal secretion of water in miniature pigs. J Nutr 1999 129, 410–418.Google Scholar
Ehrlein, H & Stockmann, AIntestinal absorption of nutrients is not influenced by soy fiber and does not differ between oligomeric and polymeric enteral diets. Dig Dis Sci 1998 43, 2099–2110.CrossRefGoogle Scholar
Go, JT, Harper, RG, Sia, CG, Teichberg, S & Wapnir, RAOral rehydration solutions: increased water and sodium absorption by addition of a viscosity-enhancing agent in a rat model of chronic osmotic diarrhea. J Pediatr Gastroenterol Nutr 1994 19, 410–416.Google Scholar
Hampson, DJPostweaning Escherichia coli diarrhoea in pigs. In Escherichia Coli in Domestic Animals and Humans, pp. 171–191 [Gyles, CJ, editor]. Wallingford, UK: CAB International. 1994Google Scholar
Hor, M, Rimpler, H & Heinrich, MInhibition of intestinal chloride secretion by proanthocyanidins from Guazuma ulmifolia. Planta Med 1995 61, 208–212.CrossRefGoogle ScholarPubMed
Hunt, JB, Carnaby, S & Farthing, MJAssessment of water and solute absorption from experimental hypotonic and established oral rehydration solutions in secreting rat intestine. Aliment Pharmacol Ther 1991 5, 273–281.CrossRefGoogle ScholarPubMed
Karmini, M, Affandi, E & Hermana, HThe inhibitory effect of tempe on Escherichia coli infection. In Proceedings of the International Tempe Symposium, pp. 157–162. [Sudarmadji, S, Suparmo, S and Raharjo, S, editors]. Jakarta, Indonesia: Indonesian Tempe Foundation. 1997Google Scholar
Karyadi, D & Lukito, WBeneficial effects of tempeh in disease prevention and treatment. Nutr Rev 1996 54, S94–S98.CrossRefGoogle ScholarPubMed
Karyadi, D & Lukito, WFunctional food and contemporary nutrition-health paradigm: tempeh and its potential beneficial effects in disease prevention and treatment. Nutrition 2000 16, 697.CrossRefGoogle ScholarPubMed
Kiers, JL, Meijer, JC, Nout, MJ, Rombouts, FM, Nabuurs, MJ & van der Meulen, JEffect of fermented soya beans on diarrhoea and feed efficiency in weaned piglets. J Appl Microbiol 2003 95, 545–552.CrossRefGoogle ScholarPubMed
Kiers, JL, Nout, RMJ & Rombouts, FMIn vitro digestibility of processed and fermented soya bean, cowpea and maize. J Sci Food Agric 2000 80, 1325–1331.3.0.CO;2-K>CrossRefGoogle Scholar
Kiers, JL, Nout, MRJ, Rombouts, FM, Nabuurs, MJA & van der Meulen, JNet absorption of fluid in uninfected and ETEC-infected piglet small intestine: effect of osmolality. In Digestive Physiology in Pigs. Proceedings of the 8th Symposium, pp. 277–279 [Lindberg, JE and Ogle, B, editors]. Wallingford, UK: CABI Publishing. 2001Google Scholar
Kiers, JL, Nout, MJ, Rombouts, FM, Nabuurs, MJ & van der Meulen, JInhibition of adhesion of enterotoxigenic Escherichia coli K88 by soya bean tempe. Lett Appl Microbiol 2002 35, 311–315.CrossRefGoogle ScholarPubMed
Kobayasi, S, Okazaki, N & Koseki, TPurification and characterization of an antibiotic substance produced from Rhizopus oligosporus IFO 8631. Biosci Biotechnol Biochem 1992 56, 94–98.CrossRefGoogle ScholarPubMed
Macfarlane, BJ, van der Riet, WB, Bothwell, TH, Baynes, RD, Siegenberg, D, Schmidt, U, Tal, A, Taylor, JR & Mayet, FEffect of traditional oriental soy products on iron absorption. Am J Clin Nutr 1990 51, 873–880.CrossRefGoogle ScholarPubMed
Macleod, RJ, Bennett, HP & Hamilton, JRInhibition of intestinal secretion by rice. Lancet 1995 346, 90–92.CrossRefGoogle ScholarPubMed
Mathews, CJ, MacLeod, RJ, Zheng, SX, Hanrahan, JW, Bennett, HP & Hamilton, JRCharacterization of the inhibitory effect of boiled rice on intestinal chloride secretion in guinea pig crypt cells. Gastroenterology 1999 116, 1342–1347.CrossRefGoogle ScholarPubMed
Mital, BK & Garg, SKTempeh - technology and food value. Food Rev Int 1990 6, 213–224.CrossRefGoogle Scholar
Mynott, TL, Guandalini, S, Raimondi, F & Fasano, ABromelain prevents secretion caused by Vibrio cholerae and Escherichia coli enterotoxins in rabbit ileum in vitro. Gastroenterology 1997 113, 175–184.CrossRefGoogle ScholarPubMed
Mynott, TL, Luke, RK & Chandler, DSOral administration of protease inhibits enterotoxigenic Escherichia coli receptor activity in piglet small intestine. Gut 1996 38, 28–32.CrossRefGoogle ScholarPubMed
Nabuurs, MJ, Hoogendoorn, A, van Zijderveld, FG & van der Klis, JDA long-term perfusion test to measure net absorption in the small intestine of weaned pigs. Res Vet Sci 1993 55, 108–114.CrossRefGoogle ScholarPubMed
Nout, MJR, De Dreu, MA, Zuurbier, AM & Bonants-van Laarhoven, TMGEcology of controlled soybean acidification for tempe manufacture. Food Microbiol 1987 4, 165–172.CrossRefGoogle Scholar
Nout, MJR & Kiers, JLTempe fermentation, innovation and functionality: update into the third millennium. J Appl Microbiol 2005 98, 789–805.CrossRefGoogle Scholar
Osundahunsi, OF & Aworh, OCA preliminary study on the use of tempe-based formula as a weaning diet in Nigeria. Plant Foods Hum Nutr 2002 57, 365–376.CrossRefGoogle Scholar
Pfeiffer, A, Schmidt, T & Kaess, HThe role of osmolality in the absorption of a nutrient solution. Aliment Pharmacol Ther 1998 12, 281–286.CrossRefGoogle ScholarPubMed
Pillai, GV, Brueton, MJ, Burston, D & Sandhu, BKEvaluation of the effects of varying solute content on the efficacy of oral rehydration solutions in a rat model of secretory diarrhoea. J Pediatr Gastroenterol Nutr 1994a 18, 457–460.Google Scholar
Pillai, GV, Brueton, MJ, Burston, D & Sandhu, BKStudies of water movement across the gut using oral rehydration solutions in a rat perfusion model. Aliment Pharmacol Ther 1994b 8, 555–558.CrossRefGoogle Scholar
Rabbani, GH, Lu, RB, Horvath, K & Lebenthal, EShortchain glucose polymer and anthracene-9-carboxylic acid inhibit water and electrolyte secretion induced by dibutyryl cyclic AMP in the small intestine. Gastroenterology 1991 101, 1046–1053.CrossRefGoogle ScholarPubMed
Sellwood, R, Gibbons, RA, Jones, GW & Rutter, JMAdhesion of enteropathogenic Escherichia coli to pig intestinal brush borders: the existence of two pig phenotypes. J Med Microbiol 1975 8, 405–411.CrossRefGoogle ScholarPubMed
Turvill, JL, Wapnir, RA, Wingertzahn, MA, Teichberg, S & Farthing, MJCholera toxin-induced secretion in rats is reduced by a soluble fiber, gum arabic. Dig Dis Sci 2000 45, 946–951.CrossRefGoogle ScholarPubMed
Wang, HL, Ellis, JJ & Hesseltine, CWAntibacterial activity produced by molds commonly used in oriental food fermentations. Mycologia 1972 64, 218–221.CrossRefGoogle ScholarPubMed
Wang, HL, Ruttle, DI & Hesseltine, CWAntibacterial compound from a soybean product fermented by Rhizopus oligosporus. Proc Soc Exp Biol Med 1969 131, 579–583.CrossRefGoogle ScholarPubMed
Wingertzahn, MA, Teichberg, S & Wapnir, RAModified starch enhances absorption and accelerates recovery in experimental diarrhea in rats. Pediatr Res 1999 45, 397–402.CrossRefGoogle ScholarPubMed
World Health Organization World Health Organization Report on Infectious Diseases. Removing Obstacles to Healthy Development Geneva: WHO. 1999Google Scholar