Hostname: page-component-586b7cd67f-dlnhk Total loading time: 0 Render date: 2024-11-26T23:54:06.443Z Has data issue: false hasContentIssue false
  • English
  • Français

Effect of level of nutrition on splanchnic blood flow and oxygen consumption in sheep*

Published online by Cambridge University Press:  09 March 2007

D. G. Burrin ,
C. L. Ferrell ,
J. H. Eisemann ,
R. A. Britton  and
J. A. Nienaber
D. G. Burrin
Affiliation:
Department of Animal Sciences, University of Nebraska, Lincoln, Nebraska 68583-0908, USA
C. L. Ferrell
Affiliation:
Roman L. Hruska Meat Animal Research Center, Agricultural Research Service, USDA, Clay Center, Nebraska, USA
J. H. Eisemann
Affiliation:
Roman L. Hruska Meat Animal Research Center, Agricultural Research Service, USDA, Clay Center, Nebraska, USA
R. A. Britton
Affiliation:
Department of Animal Sciences, University of Nebraska, Lincoln, Nebraska 68583-0908, USA
J. A. Nienaber
Affiliation:
Roman L. Hruska Meat Animal Research Center, Agricultural Research Service, USDA, Clay Center, Nebraska, USA
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The objective of the present study was to measure changes in splanchnic blood flow and oxygen consumption in sheep fed on a high-concentrate diet ad lib. (ADLIB) or an amount sufficient to maintain body-weight (MAINT) for 21 d. Eleven ram lambs were surgically implanted with chronic indwelling catheters in the portal, hepatic and mesenteric veins and mesenteric artery to measure blood flow and net O2 flux through the liver and portal-drained viscera (PDV). During the 21 d period, PDV (P < 0.05) and liver (P < 0.01) blood flow increased in ADLIB and decreased in MAINT lambs (treatment x day, linear). After 21 d, O2 consumptions in PDV and liver of MAINT lambs were 37 and 63% lower than in ADLIB lambs. In the control period, total splanchnic tissues represented an average of 52% of whole body O2 consumption. After 21 d, the relative contributions of PDV and liver to whole-body O2 consumption were 28 and 41% in ADLIB and 19 and 22% in MAINT lambs respectively. Allometric regression variables indicate that liver O2 consumption responds more rapidly to changes in metabolizable energy intake than portal O2 consumption. These results indicate that blood flow and O2 consumption in both PDV and liver are related to level of nutrition. Furthermore, splanchnic tissues represent a significant component of whole-body O2 consumption that is subject to manipulation by level of nutrition.

Keywords

Oxygen consumptionSplanchnic blood flowSheep
Type
Research Article
Information
British Journal of Nutrition , Volume 62 , Issue 1 , July 1989 , pp. 23 - 34
Copyright
Copyright © The Nutrition Society 1989

References

REFERENCES

Bell, A.W., Battaglia, F.C. & Meschia, G. (1987) Relation between metabolic rate and body size in the ovine fetus. Journal of Nutrition 117, 1181–1186.CrossRefGoogle ScholarPubMed
Bensadoun, A., Paladines, O.L. & Reid, J.T. (1962). Effect of level of intake and physical form of the diet on plasma glucose concentration and volatile fatty acid absorption in ruminants. Journal of Dairy Science 45, 1203–1210.CrossRefGoogle Scholar
Brody, S. (1945). Bioenergetics and Growth. New York: Reinhold Publishing Company.Google Scholar
Burrin, D.G., Bauer, M.L., Dubrovin, L.C., Britton, R.A. & Ferrell, C.L. (1987). Nutrient restriction decreases visceral organ size and metabolic activity in sheep. Journal of Animal Science 65, Suppl. 1, 87 Abstr.Google Scholar
Chou, C.C., Hsieh, C.P., Yu, Y.M., Kvietys, P., Yu, L.C., Pittman, R. & Dabney, J.M. (1976). Localization of mesenteric hyperemia during digestion in dogs. American Journal of Physiology 230, 583–589.CrossRefGoogle ScholarPubMed
Dobson, A., Barnes, R.J. & Comline, R.S. (1981). Changes in the sources of hepatic portal blood flow with feeding in the sheep. Physiologist 24, 15 Abstr.Google Scholar
Edelstone, D.I. & Holzman, I.R. (1981). Gastrointestinal tract O2 uptake and regional blood flow during digestion in conscious newborn lambs. American Journal of Physiology 241, G289–G293.Google Scholar
Eisemann, J.H., Huntington, G.B. & Ferrell, C.L. (1987). Blood flow to hindquarters of steers measured by transit time ultrasound and indicator dilution. Journal of Dairy Science 70, 1385–1390.CrossRefGoogle ScholarPubMed
Ferrell, C.L. & Jenkins, T.G. (1984). Energy utilization by mature, non-pregnant, non-lactating cows of different types. Journal of Animal Science 58, 234–243.CrossRefGoogle Scholar
Ferrell, C.L. & Koong, L.J. (1985). Response of body organs of lambs to differing nutritional treatments. In Energy Metabolism of Farm Animals, pp. 26–29 [Moe, P.W., Tyrrell, H.F. and Reynolds, P.J., editors]. European Association of Animal Production, Publication no. 32. Totowa, New Jersey: Rowman and Littlefield.Google Scholar
Ferrell, C.L., Koong, L.J. & Nienaber, J.A. (1986). Effect of previous nutrition on body composition and maintenance energy costs of growing lambs. British Journal of Nutrition 56, 595–605.CrossRefGoogle ScholarPubMed
Graham, N.McC., Searle, T.W. & Griffiths, D.A. (1974). Basal metabolic rate in lambs and young sheep. Australian Journal of Agricultural Research 25, 957–971.CrossRefGoogle Scholar
Holliday, M.A., Potter, D., Jarrah, A. & Bearg, S. (1967). The relation of metabolic rate to body-weight and organ size. Pediatrician Research 1, 185–195.CrossRefGoogle ScholarPubMed
Huntington, G.B. (1984). Relationship of portal blood flow to metabolizable energy intake of cattle. Canadian Journal of Animal Science 64, Suppl. 1, 16–17.CrossRefGoogle Scholar
Huntington, G.B. & Prior, R.L. (1983). Digestion and absorption of nutrients by beef heifers fed a high concentrate diet. Journal of Nutrition 113, 2280–2288.CrossRefGoogle ScholarPubMed
Huntington, G.B., Prior, R.L. & Britton, R.A. (1980). Glucose and lactate absorption and metabolic interrelationships in lambs switched from low to high concentrate diets. Journal of Nutrition 110, 1904–1910.CrossRefGoogle ScholarPubMed
Huntington, G.B. & Reynolds, C.K. (1986). Blood flow and nutrient flux across stomach and post-stomach tissues in beef steers. Federation Proceedings 45, 606.Google Scholar
Huntington, G.B. & Tyrrell, H.F. (1985). Oxygen consumption by portal-drained viscera of cattle: comparison of analytical methods and relationship to whole-body oxygen consumption. Journal of Dairy Science 68, 2727–2731.CrossRefGoogle ScholarPubMed
Huntington, G.B., Varga, G.A., Reynolds, P.J. & Tyrrell, H.F. (1985). Net absorption of nutrients and oxygen consumption by portal-drained viscera in relation to energy metabolism by Holstein cattle. In Energy Metabolism of Farm Animals, pp. 22–25 [Moe, P.W., Tyrrell, H.F. and Reynolds, P.J., editors]. European Association of Animal Production, no. 32. Totowa, New Jersey: Rowman and Littlefield.Google Scholar
Jenkins, T.G. & Ferrell, C.L. (1983). Nutrient requirements to maintain weight of mature, non-lactating, non-pregnant cows of four diverse breed types. Journal of Animal Science 56, 761–770.CrossRefGoogle Scholar
Katz, M.L. & Bergman, E.N. (1969). Simultaneous measurements of hepatic and portal venous blood flow in the sheep and dog. American Journal of Physiology 216, 946–952.CrossRefGoogle ScholarPubMed
Kleiber, M. (1947). Body size and metabolic rate. Physiological Reviews 27, 511–541.CrossRefGoogle ScholarPubMed
Koong, L.J., Nienaber, J.A., Pekas, J.C. & Yen, J.T. (1982). Effects of plane of nutrition on organ size and fasting heat production in pigs. Journal of Nutrition 112, 1638–1642.CrossRefGoogle ScholarPubMed
Lautt, W.W. (1980). Control of hepatic arterial blood flow: independence from liver metabolic activity. American Journal of Physiology 239, H559–H564.Google ScholarPubMed
Lautt, W.W. (1983). Relationship between hepatic blood flow and overall metabolism: the hepatic arterial buffer response. Federation Proceedings 42, 1662–1666.Google Scholar
Ledger, H.P. & Sayers, A.R. (1977). The utilization of dietary energy by steers during periods of restricted food intake and subsequent realimentation. I. The effect of time on maintenance requirements of steers held at constant live weights. Journal of Agricultural Science 88, 11–26.CrossRefGoogle Scholar
Lomax, M.A. & Baird, G.D. (1983). Blood flow and nutrient exchange across the liver and gut of the dairy cow. British Journal of Nutrition 49, 481–496.CrossRefGoogle ScholarPubMed
Marston, H.R. (1948). Energy transactions in sheep. I. The basal heat production and the heat increment. Australian Journal of Science Research B1, 91–129.Google Scholar
Munro, H.N. (1969). The evolution of protein metabolism in mammals. In Mammalian Protein Metabolism, vol. 3, pp. 151–171 [Munro, H.N., editor]. New York: Academic Press.Google ScholarPubMed
National Research Council (1984). Nutrient Requirements of Beef Cattle. Washington, DC: National Academy of Sciences.Google Scholar
Nienaber, J.A. & Maddy, A.C. (1985). Temperature-controlled multiple-chamber indirect-calorimetry. Design and operation. Transactions of the ASAE 28, 555–562.CrossRefGoogle Scholar
Reynolds, C.K., Huntington, G.B., Tyrrell, H.F. & Reynolds, P.J. (1986). Splanchnic tissue and whole animal oxygen consumption by lactating Holstein cows. Journal of Dairy Science 69, Suppl. 1, 193.Google Scholar
Reynolds, C.K. & Tyrrell, H.F. (1987). Effect of diet intake on net visceral tissue metabolism in growing beef heifers. Journal of Animal Science 65, Suppl. 1, 477.Google Scholar
Richardson, P.D.I. & Withrington, P.G. (1982). Physiological regulation of the hepatic circulation. Annual Review of Physiology 44, 57–69.CrossRefGoogle ScholarPubMed
SAS (1982). SAS User's Guide: Statistics. Cary, NC: Statistical Analysis System Institute Inc.Google Scholar
Schaefer, A.L. & Krishnamurti, C.R. (1984). Whole body and tissue fractional protein synthesis in the ovine fetus in utero. British Journal of Nutrition 52, 359–369.CrossRefGoogle ScholarPubMed
Sellers, A.F., Stevens, C.E., Dobson, A. & McLeod, F.D. (1964). Arterial blood flow to the ruminant stomach. American Journal of Physiology 207, 371–377.CrossRefGoogle Scholar
Shepherd, A.P. (1982). Local control of intestinal oxygenation and blood flow. Annual Review of Physiology 44, 13–27.CrossRefGoogle ScholarPubMed
Smith, N.E. & Baldwin, R.L. (1974). Effects of breed, pregnancy and lactation on weight of organs and tissues in dairy cattle. Journal of Dairy Science 57, 1055–1060.CrossRefGoogle Scholar
Steel, R.G.D. & Torrie, J.H. (1980). Principles and Procedures of Statistics. New York: McGraw-Hill Book Co.Google Scholar
Ushioda, E., Nuwayhid, B., Tabsh, K., Erkkola, R., Brinkman, R. III & Assali, N.S. (1982). Mixing problems in using indicators for measuring regional blood flow. American Journal of Obstetrics and Gynecology 142, 74–86.CrossRefGoogle ScholarPubMed
Vatner, S.F., Franklin, D. & Van Cilters, R.L. (1970). Mesenteric vasoactivity associated with eating and digestion in the conscious dog. American Journal of Physiology 219, 170–174.CrossRefGoogle ScholarPubMed
Webster, A.J.F. (1981). The energetic efficiency of metabolism. Proceedings of the Nutrition Society 40, 121–128.CrossRefGoogle ScholarPubMed
Webster, A.J.F., Osuji, P.O., White, F. & Ingram, J.F. (1975). The influence of food intake on portal blood flow and heat production in the digestive tract of sheep. British Journal of Nutrition 34, 125–139.CrossRefGoogle ScholarPubMed
Wieghart, M., Slepetis, R., Elliot, J.M. & Smith, D.F. (1986). Glucose absorption and hepatic gluconeogenesis in dairy cows fed diets varying in forage content. Journal of Nutrition 116, 839–850.CrossRefGoogle ScholarPubMed