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The effect of ingestion of guar gum on ileostomy effluent

Published online by Cambridge University Press:  09 March 2007

S. E. Higham  and
N. W. Read
S. E. Higham
Affiliation:
Centre for Human Nutrition, The University of Sheffield, Northern General Hospital, Herries Road, Sheffield S5 7AU
N. W. Read
Affiliation:
Centre for Human Nutrition, The University of Sheffield, Northern General Hospital, Herries Road, Sheffield S5 7AU
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Abstract

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Randomized, paired studies were carried out on five healthy volunteers equipped with terminal ileostomies to investigate the effect of incorporating 15 g of the viscous polysaccharide guar gum in the normal diet on the volume, weight, composition and physical properties of ileostomy effluent. Subjects ate an identical diet during two 5 d study periods, which were separated by 2 d. Outputs of fat, protein, sodium, potassium, dry weight and water were all increased during guar gum administration, but outputs of carbohydrate, calcium and phosphorus were not significantly altered. Mouth-to-stoma transit was not significantly affected and, surprisingly, the viscosity of the ileostomy effluent was reduced by guar gum. These results show that it is not always possible to predict what will happen to small intestinal function when guar gum is added to the diet from experiments carried out when guar gum is administered alone or with glucose. While our findings show that guar gum will reduce fat absorption, the mechanisms involved are more sophisticated than hitherto envisaged.

Keywords

Guar gumIleostomy effluent
Type
Effects of Complex Carbohydrates on Nutrient Absortion
Information
British Journal of Nutrition , Volume 67 , Issue 1 , January 1992 , pp. 115 - 122
Copyright
Copyright © The Nutrition Society 1992

References

Adrian, J. (1976). Gums and hydrocolloids in nutrition. World Review of Nutrition and Dietetics 25, 189–216.CrossRefGoogle ScholarPubMed
Blackburn, N. A., Redfern, J. S., Jarjis, H., Holgate, A. M., Hanning, I., Scarpello, J. H. B., Johnson, I. T. & Read, N. W. (1984). The mechanism of action of guar gum in improving glucose tolerance in man. Clinical Science 66, 329–336.Google Scholar
Bueno, L., Praddaude, F., Fioramonti, J. & Ruckenbusch, Y. (1981). Effect of dietary fibre on gastrointestinal motility and jejunal transit time in dogs. Gastroenterology 80, 701–707.CrossRefGoogle ScholarPubMed
Dunaiff, G. & Schneeman, B. O. (1981). The effect of dietary fibre on the pancreatic excretory function. American Journal of Nutrition 34, 1034–1035.Google Scholar
Edwards, C. A., Blackburn, N. A., Craigen, L., Davison, P., Tomlin, J., Sugden, K., Johnson, I. T. & Read, N. W. (1987). Viscosity of food gums determined in vitro related to their hypoglycemic actions. American Journal of Clinical Nutrition 46, 72–77.Google Scholar
Ellis, P. R., Morris, E. R. & Low, A. G. (1986). Guar gum: the importance of reporting data on its physico-chemical properties. Diabetic Medicine 3, 490–491.CrossRefGoogle ScholarPubMed
Elsenhans, B., Zenker, D., Caspary, W. F. & Blume, R. (1984). Guaran effect on rat intestinal absorption. Gastroenterology 86, 645–653.Google Scholar
Evans, E. & Miller, D. S. (1975). Bulking agents in the treatment of obesity. Nutrition and Metabolism 18, 199–203.CrossRefGoogle ScholarPubMed
Fuessl, H. S., Williams, G., Adrian, T. E. & Bloom, S. R. (1987). Guar sprinkled on food: effect on glycaemic control, plasma lipids, and gut hormones in non-insulin dependent diabetic patients. Diabetic Medicine 4, 463–468.Google Scholar
Higham, S. E. & Read, N. W. (1990). Effect of ingestion of fat on ileostomy effluent. Gut 31, 435–438.CrossRefGoogle ScholarPubMed
Isaakson, G., Lundquist, I. & Ihse, I. (1982). Effect of dietary fibre on pancreatic enzyme activity in vitro. Gastroenterology 82, 918–924.CrossRefGoogle Scholar
Jenkins, D. J. A., Leeds, A. R., Gasull, M. A., Cochet, B. & Alberti, G. M. M. (1977). Decrease in postprandial insulin and glucose concentrations by guar and pectin. Annals of Internal Medicine 86, 20–23.Google Scholar
McNeil, N. I. (1984). The contribution of the large intestine to energy supplies in man. American Journal of Clinical Nutrition 39, 338–342.Google Scholar
Meyer, J. H. & Doty, J. E. (1988). GI transit and absorption of solid food: multiple effects of guar. American Journal of Clinical Nutrition 48, 267–273.CrossRefGoogle ScholarPubMed
Read, N. W. (1986). Dietary fibre and bowel transit. Dietary Fibre Basic and Clinical Aspects pp. 91–100 [Vahouny, G. V. and Kritchevsky, D., editors]. New York and London: Plenum Press.Google Scholar
Sandberg, A. S., Ahderinne, R., Andersson, H., Hallgren, B. & Hulten, L. (1983). The effect of citrus pectin on the absorption of nutrients in the small intestine. Human Nutrition: Clinical Nutrition 37C, 171–183.Google Scholar
Schnell, M., Pacy, J. F. & Judd, P. A. (1985). Effect of guar gum intake on chylomicron size and composition in the rat. Proceedings of the Nutrition Society 44, 17A.Google Scholar
Smith, U. & Holm, G. (1982). Effects of a modified guar gum preparation on glucose and lipid levels in diabetics and healthy volunteers. Atherosclerosis 45, 1–10.Google Scholar
Sommer, H. & Kasper, H. (1980). The effect of dietary fibre on the pancreatic excretory function. Hepatogastroenterology 27, 477–483.Google ScholarPubMed
Stephen, A. M. & Cummings, J. H. (1979). Water-holding by dietary fibre in vitro and its relationship to faecal output in man. Gut 20, 722–729.Google Scholar
Van de Kamer, J. H., Huinink, H., ten, B. & Weijers, H. A. (1949). Rapid determination of fat in faeces. Journal of Biological Chemistry 177, 347–355.Google Scholar
Varley, H. (1984). Practical Clinical Biochemistry 5th ed. London: Heinemann.Google Scholar