Hostname: page-component-586b7cd67f-l7hp2 Total loading time: 0 Render date: 2024-11-29T16:48:39.088Z Has data issue: false hasContentIssue false
  • English
  • Français

Effect of guar gum on body-weight, hunger ratings and metabolism in obese subjects

Published online by Cambridge University Press:  09 March 2007

Marcin Krotkiewski
Marcin Krotkiewski
Affiliation:
Department of Rehabilitation Medicine, Sahlgren's Hospital, University of Göteborg, Göteborg, Sweden
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. The effect of a palatable granulated guar-gum preparation (10 g twice daily) was studied in obese subjects. The acute effect of a single dose of guar gum to reduce the peak postprandial whole blood glucose levels (about 10%) was verified. Following long-term treatment, a further reduction was seen in the obese subjects with the highest postprandial glucose levels. Since the postprandial plasma insulin levels were essentially unchanged, this finding suggested an increased responsiveness to insulin. Total serum cholesterol levels were significantly reduced following long-term treatment but serum α-cholesterol levels, representing the high-density-lipoprotein fraction, was unchanged.

2. Body-weight was significantly reduced during guar-gum treatment even though the patients were asked to maintain their normal dietary habits. Daily hunger ratings recorded for up to 10 weeks showed that guar gum reduced hunger significantly better than commercially available bran taken in the same way.

3. Thus, guar gum seemed to influence carbohydrate and lipid metabolism in a beneficial way in obese subjects. The reduction in hunger would offer an additional benefit to these patients.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 52 , Issue 1 , July 1984 , pp. 97 - 105
Copyright
Copyright © The Nutrition Society 1984

References

REFERENCES

Borner, K. & Klose, E. (1977). Journal of Clinical Chemistry 15, 121–130.Google Scholar
Forbes, G. B., Gallup, J. & Hurch, J. B. (1961). Science 133, 101–102.CrossRefGoogle Scholar
Holt, S., Heading, R. C., Carter, D. C., Prescott, L. F. & Tothill, P. (1979). Lancet ii, 636–639.CrossRefGoogle Scholar
Jenkins, D. J. A., Goff, D. V., Leeds, A. R., Alberti, K. G. M., Wolver, T. M. S., Gasull, M. A. & Hockaday, T. D. R. (1976). Lancet ii, 172–174.CrossRefGoogle Scholar
Jenkins, D. J. A., Leeds, A. R., Gassull, M. A., Cochet, B. & Alberti, K. G. M. M. (1977). Annals of Internal Medicine 86, 20–23.CrossRefGoogle Scholar
Jenkins, D. J. A., Leeds, A. R., Slavin, B., Mann, J. & Jepson, E. M. (1979). American Journal of Clinical Nutrition 32, 16–18.CrossRefGoogle Scholar
Jenkins, D. J. A., Reynolds, R., Slavin, B., Leeds, A. R., Jenkins, A. L. & Jepson, E. M. (1980). American Journal of Clinical Nutrition 33, 575–581.CrossRefGoogle Scholar
Jenkins, D. J. A., Wolever, T. M. S., Leeds, A. R., Gassull, M. A., Haisman, P., Dilawari, J., Goff, D., Metz, G. L. & Alberti, K. G. M. M. (1978). British medical journal i, 1392–1394.CrossRefGoogle Scholar
Metropolitan Life Insurance Co. (1959). Statistical Bulletin 40, 1–4.Google Scholar
Morgan, L. M., Goulder, T. J., Triolakis, D., Marks, V. & Alberti, K. G. M. M. (1979). Diabetologia 17, 85–89.CrossRefGoogle Scholar
Sköldborn, H. & Arvidsson, M. (1972). Proceedings of the Sixth International Nordic Meeting on Clinical Physics. Acta Radiologica 313, Suppl., 233.Google Scholar
Smith, U. & Holm, G. (1982). Atherosclerosis 45, 1–10.CrossRefGoogle Scholar
Tuomilehto, J., Voutilainen, E., Huutunen, J., Vinni, S. & Homan, K. (1980). Acta Medica Scandinavica 208, 45–48.CrossRefGoogle Scholar
Wahlefeld, A. W. (1974). In Methods of Enzymatic analysis, p. 1831 [Bergmeyer, H. V., editor]. New york: Academic press.CrossRefGoogle Scholar
Wiklund, O., Fager, G., Craig, I. H., Wilhelmsson, C.-E., Vedin, A., Olofsson, S.-O., Bondjers, G. & Wilhelmsen, L. (1980). Scandinavian Journal of Clinical and Laboratory Investigations 40, 239–247.CrossRefGoogle Scholar
Wilmshurst, P. & Crawley, J. C. W. (1980). British Journal of Nutrition 44, 1–6.CrossRefGoogle Scholar