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The effect of dihomo-γ-linolenic acid (20: 3, n-6) on the composition of phospholipid fatty acids in the liver of rats deficient in essential fatty acids

Published online by Cambridge University Press:  09 March 2007

A. G. Hassam  and
M. A. Crawford
A. G. Hassam
Affiliation:
Department of Biochemistry, Nuffield Laboratories of Comparative Medicine, Institute of Zoology, The Zoological Society of London, Regent's Park, London NW1 4RY
M. A. Crawford
Affiliation:
Department of Biochemistry, Nuffield Laboratories of Comparative Medicine, Institute of Zoology, The Zoological Society of London, Regent's Park, London NW1 4RY
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Abstract

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1. Rats were fed on either a diet deficient in essential fatty acid (EFA) or one supplemented with dihomo-γ-linolenic acid (20:3,n-6) at levels that represented 0.25, 0.5, 1.0 and 2.0% of the dietary energy.

2. Supplementation of the diet of EFA-deficient animals with 20:3,n-6 reversed most of the fatty acid changes induced in the liver phospholipid fraction.

3. The EFA potency of 20:3,n-6 was found to be similar to that of γ-linolenic acid (18:3,n-6) which has been shown to be higher than that of linoleic acid (18:2,n-6).

Type
Short Papers
Information
British Journal of Nutrition , Volume 40 , Issue 1 , July 1978 , pp. 155 - 157
Copyright
Copyright © The Nutrition Society 1978

References

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