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Effect of dietary magnesium level on urinary and faecal excretion of calcium, magnesium and phosphorus in adult, ovariectomized cats

Published online by Cambridge University Press:  09 March 2007

F. J. H. Pastoor ,
A. Th. Van Tklooster ,
R. Opitz  and
A. C. Beynen
F. J. H. Pastoor
Affiliation:
Department of Laboratory Animal Science, Utrecht University, Utrecht, The Netherlands
A. Th. Van Tklooster
Affiliation:
Department of Large Animal Medicine and Nutrition, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
R. Opitz
Affiliation:
Department of Laboratory Animal Science, Utrecht University, Utrecht, The Netherlands
A. C. Beynen
Affiliation:
Department of Laboratory Animal Science, Utrecht University, Utrecht, The Netherlands Department of Large Animal Medicine and Nutrition, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
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Abstract

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Dietary Mg restriction is generally considered to contribute to the prevention of struvite urolithiasis in cats, but its effects on faecal and urinary excretion of Ca and P have not been systematically investigated. The present study seeks to fill the gap. In a 4×4-week crossover study, ovariectomized cats were fed on purified diets containing either 0·40, 0·79,1·59 or 3·17 mmol Mg/MJ (0·19, 0·38,0·76 and 1·52 g Mg/kg diet). Increasing the dietary Mg level from 0·40 to 3·17 mmol Mg/MJ by the addition of extra MgCO3 raised urinary and faecal excretion of Mg from 0·14 to 0·68 mmol/MJ and from 0·28 to 1·66 mmoI/MJ respectively. The 8-fold increase in Mg intake significantly raised urinary excretion of Ca from 0·06 to respectively when the dietary Mg level was raised from 0·40 to 3·17 mmol/MJ. A dietary level of 0·40 mmol Mg/MJ (0·19 g Mg/kg diet) was found to be sufficient to maintain Mg balance in the adult ovariectomized cats fed on the purified diet.

Keywords

MagnesiumMineral excretionUrolithiasisCat
Type
Mineral metabolism in companion animals
Information
British Journal of Nutrition , Volume 74 , Issue 1 , July 1995 , pp. 77 - 84
Copyright
Copyright © The Nutrition Society 1995

References

REFERENCES

Bergstra, A. E., Lemmens, A. G. & Beynen, A. C. (1993) Dietary fructose vs. glucose stimulates nephro-calcinogenesis in female rats. Journal of Nutrition 123, 1320–1327.CrossRefGoogle ScholarPubMed
Brink, E. J., Beynen, A. C, Dekker, P. R., Van Beresteijn, E. C. H. & Van der Meer, R. (1992) Interaction of calcium and phosphate decreases ileal magnesium solubility and apparent magnesium absorption in rats. Journal of Nutrition 122, 580–586.CrossRefGoogle ScholarPubMed
Buffington, C. A., Cook, N. E., Rogers, Q. R. & Morris, J. G. (1989) The role of diet in feline struvite urolithiasis syndrome. In Nutrition of the Dog and Cat, pp. 357–380 [Burger, I.H. and Rivers, J. P. W., editors]. Cambridge: Cambridge University Press.Google Scholar
Buffington, C. A., Rogers, Q. R. & Morris, J. G. (1985) Feline struvite urolithiasis: magnesium effect depends on urinary pH. Feline Practice 15(6), 29–33.Google Scholar
Carbone, M. G. (1965) Phosphocrystalluria and urethral obstruction in the cat. Journal of the American Veterinary Medical Association 147, 1195–1200.Google ScholarPubMed
Carney, S. L., Wong, N. L. M., Quamme, G. A. & Dirks, J. H. (1980) Effect of magnesium deficiency on renal magnesium and calcium transport in the rat. Journal of Clinical Investigation 65, 180–188.CrossRefGoogle ScholarPubMed
Chesley, L. C. & Tepper, I. (1958) Some effects of magnesium loading upon renal excretion of magnesium and certain other electrolytes. Journal of Clinical Investigation 37, 1362–1372.CrossRefGoogle ScholarPubMed
Clark, I. (1968) Effects of magnesium ions on calcium and phosphorus metabolism. American Journal of Physiology 214, 348–356.CrossRefGoogle ScholarPubMed
Clark, I. (1969) Metabolic interrelations of calcium, magnesium, and phosphate. American Journal of Physiology 217, 871–878.CrossRefGoogle ScholarPubMed
Cruikshank, D. P., Pitkin, R. M., Donnelly, E. & Reynolds, W. A. (1981) Urinary magnesium, calcium, and phosphate excretion during magnesium sulfate infusion. Obstetrics and Gynecology 58, 430–434.Google ScholarPubMed
Feldmann, B. M., Kennedy, B. M. & Schelstraete, M. (1977) Dietary minerals and the feline urologic syndrome. Feline Practice 7(3), 39–45.Google Scholar
Finco, D. R., Barsanti, J. A. & Crowell, W. A. (1985) Characterization of magnesium-induced urinary disease in the cat and comparison with feline urologic syndrome. American Journal of Veterinary Research 46, 391–400.Google Scholar
Graser, D. H., Hamar, D. W. & Lewis, L. D. (1981) The consistency of dietary minerals in commercial cat foods and their relationship to feline urolithiasis. Feline Practice 11(2), 41–47.Google Scholar
Hesse, A. & Sanders, G. (1985) A survey of urolithiasis in cats. Journal of Small Animal Practice 26, 465–476.CrossRefGoogle Scholar
Kallfelz, F. A., Bressett, J. D. & Wallace, R. J. (1980) Urethral obstruction in random source and SPF male cats induced by high levels of dietary magnesium or magnesium and phosphorus. Feline Practice 10(4), 25–35.Google Scholar
Lawler, D. F., Sjolin, D. W. & Collins, J. E. (1985) Incidence rates of feline lower urinary tract disease in the United States. Feline Practice 15(5), 13–16.Google Scholar
Lewis, L. D., Chow, F. H. C, Taton, G. F. & Hamar, D. W. (1978) Effects of various dietary mineral concentrations on occurrence of feline urolithiasis. Journal of the American Veterinary Medical Association 172, 559–563.Google ScholarPubMed
Mars, Y. W. H. M., Lemmens, A. G. & Beynen, A. C. (1988) Dietary phosphorus and nephrocalcinosis in female rats. Nutrition Reports International 38, 249–258.Google Scholar
National Research Council (1986) Nutrient Requirements of Cats. Washington DC: National Academy Press.Google Scholar
Pastoor, F. J. H. (1993) Interactions of dietary minerals in the cat. PhD Thesis, Utrecht University, The Netherlands.Google Scholar
Pastoor, F. J. H., Van 't Klooster, A. Th. & Beynen, A. C. (1990) An alternative method for the quantitative collection of faeces and urine of cats as validated by the determination of mineral balance. Zeitschrift für Versuchstierkunde 33, 259–263.Google ScholarPubMed
Pastoor, F. J. H., Van 't Klooster, A. Th., Mathot, J. N. J. J. & Beynen, A. C. (1994) Increasing calcium intakes lower urinary concentrations of phosphorus and magnesium in adult ovariectomized cats. Journal of Nutrition 124, 299–304.CrossRefGoogle ScholarPubMed
Rude, R. K. & Singer, F. R. (1981) Magnesium deficiency and excess. Annual Review of Medicine 32, 245–259.CrossRefGoogle ScholarPubMed
Sauer, L. S., Hamar, D. & Lewis, L. D. (1985) Effect of dietary mineral composition on urinary mineral concentration and excretion by the cat. Feline Practice 15(4), 10–15.Google Scholar
SPSS Inc. (1988 a) SPSS/PC+ Advanced Statistics V2·0. Chicago, IL: SPSS Inc.Google Scholar
SPSS Inc. (1988 b) SPSS/PC+ TM V2·0. Base Manual. Chicago, IL: SPSS Inc.Google Scholar
Sterck, J. G. H., Ritskes-Hoitinga, J. & Beynen, A. C. (1992) Inhibitory effect of high protein intake on nephrocalcinogenesis in female rats. British Journal of Nutrition 67, 223–233.CrossRefGoogle ScholarPubMed