Hostname: page-component-745bb68f8f-s22k5 Total loading time: 0 Render date: 2025-01-10T19:15:42.676Z Has data issue: false hasContentIssue false
  • English
  • Français

The effect of a low-protein diet and a cold environment on calorie intake and body composition in the rat

Published online by Cambridge University Press:  09 March 2007

P. Schmida  and
Elise M. Widdowson
P. Schmida
Affiliation:
Medical Research Council Department of Experimental Medicine, University of Cambridge
Elise M. Widdowson
Affiliation:
Medical Research Council Department of Experimental Medicine, University of Cambridge
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Rats 10 weeks old were fed for 9 weeks either on a stock diet containing 17% protein, or on a low-protein diet prepared from the stock diet with added glucose, minerals and vitamins. Half the animals on each diet were kept at room temperature (21°) and half in a cold environment (5°).

2. The calorie intake of the animals kept at 5° on both diets was 60–70% higher than that of the corresponding group at 21°. The animals on the stock diet and kept at 5° gained weight but not so much as those on the same diet at 21°. The animals kept on the low-protein diet at 21° lost weight, while those on the same diet at 5° lost only a little weight initially and none thereafter.

3. On both types of diet the liver, kidneys and gastro-intestinal tract weighed more per 100 g body-weight in animals kept in the colder of the two environments; the small intestine was conspicuous in this respect.

4. The weight of the fur was greater, and the weight of the skin less per 100 g body-weight at 5° than at 21°.

5. The animals on the stock diet at 21° had most fat in their bodies, both in absolute terms and per 100 g body-weight. There were no significant differences between the other three groups.

6. The skin of the animals kept at 5° had a significantly higher collagen to N ratio than the skin of those having the same diet at 21°.

Type
Research Article
Information
British Journal of Nutrition , Volume 21 , Issue 2 , May 1967 , pp. 457 - 465
Copyright
Copyright © The Nutrition Society 1967

References

Andik, I., Bank, J., Móring, I. & Szegvári, G. (1954). Acta physiol. hung. 5, 457.Google Scholar
Andik, I. & Donhoffer, Sz. (1957). Pflügers Arch. ges. Physiol. 264, 585CrossRefGoogle Scholar
Andik, I., Donhoffer, Sz., Farkas, M. & Schmidt, P. (1963). Br. J. Nutr. 17, 257.CrossRefGoogle Scholar
Barnett, S. A., Coleman, E. M. & Manly, B. M. (1959). Q. Jl exp. Physiol. 44, 43.CrossRefGoogle Scholar
Barnett, S. A. & Widdowson, E. M. (1965). Proc. R. Soc. B 162, 502.Google Scholar
Bruce, H.M. (1963). J. Reprod. Fert. 6, 221.CrossRefGoogle Scholar
Čabak, V., Dickerson, J. W. T. & Widdowson, E. M. (1963). Br. J. Nutr. 17, 601.CrossRefGoogle Scholar
Dickerson, J. W. T. (1962). Biochem. J. 82, 47.CrossRefGoogle Scholar
Dickerson, J. W. T. & Widdowson, E. M. (1960). Biochem. J. 74, 247.CrossRefGoogle Scholar
Emery, F. E., Emery, L. M. & Schwabe, E. L. (1940). Growth 4, 17.Google Scholar
Hawk, P. B., Oser, B. L. & Summerson, W. H. (1954). Practical Physiological Chemistry, 13th ed., p. 589. London: J. and A. Churchill Ltd.Google Scholar
Heroux, O. (1961). Revue can. Biol. 20, 55.Google Scholar
Heroux, O. (1963). Fedn Proc. Fedn Am. Socs exp. Biol. 22, 789.Google Scholar
Heroux, O. & Gridgeman, N. T. (1958). Can. J. Biochem. Physiol. 36, 209.CrossRefGoogle Scholar
Neuman, R. E. & Logan, M. A. (1950). J. biol. Chem. 184, 299.CrossRefGoogle Scholar
Stanier, M. W. (1957). Br. J. Nutr. 11, 206.CrossRefGoogle Scholar
Wallace, W. M., Weil, W. B. & Taylor, A. (1958). Ciba Fdn Colloq. Ageing 4, 116.Google Scholar
Widdowson, E. M. & McCance, R. A. (1957). Br. J. Nutr. 11, 198.CrossRefGoogle Scholar
Young, D. R. & Cook, S. F. (1955). Am. J. Physiol. 181, 72.CrossRefGoogle Scholar