Hostname: page-component-78c5997874-94fs2 Total loading time: 0 Render date: 2024-11-19T04:18:13.121Z Has data issue: false hasContentIssue false
  • English
  • Français

Early post-hatching starvation delays p70 S6 kinase activation in the muscle of neonatal chicks

Published online by Cambridge University Press:  09 March 2007

Karine Bigot ,
Mohammed Taouis ,
Michel Picard  and
Sophie Tesseraud
Karine Bigot
Affiliation:
Régulation du Métabolisme des Oiseaux, Station de Recherches Avicoles, Institut National de la Recherche Agronomique, Centre de Tours-Nouzilly, 37380 Nouzilly, France
Mohammed Taouis
Affiliation:
Régulation du Métabolisme des Oiseaux, Station de Recherches Avicoles, Institut National de la Recherche Agronomique, Centre de Tours-Nouzilly, 37380 Nouzilly, France Laboratoire de Biologie Cellulaire et Moléculaire, Biotechnologies, Institut National de la Recherche Agronomique, Domaine de Vilvert, 78352 Jouy-en-Josas, France
Michel Picard
Affiliation:
Régulation du Métabolisme des Oiseaux, Station de Recherches Avicoles, Institut National de la Recherche Agronomique, Centre de Tours-Nouzilly, 37380 Nouzilly, France
Sophie Tesseraud*
Affiliation:
Régulation du Métabolisme des Oiseaux, Station de Recherches Avicoles, Institut National de la Recherche Agronomique, Centre de Tours-Nouzilly, 37380 Nouzilly, France
*
*Corresponding Author: Dr S. Tesseraud, fax +33 2 47 42 77 78, email [email protected]
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Chicken muscle ribosomal protein S6 kinase (S6K1) has been recently characterised and its enzymic activity is regulated by the nutritional and hormonal (insulin) status in vivo. The regulation of S6K1 is still unknown in neonatal chicks. The present study aimed to compare the activation of S6K1 in early-feeding (EF) and 48 h-delayed-feeding (DF) chicks from hatching to 4 d of age. During post-hatching starvation, S6K1 activity remained at the basal level measured in the control-hatched chicks. The maximum S6K1 activity was recorded on the first day of feeding with an increase of about 2·5-fold in the EF and DF chicks (P<0·01). S6K1 activity was correlated with plasma insulin level, suggesting a probable insulin-dependent S6K1 activation. The feeding-induced increase in S6K1 activity was related to its Thr389 residue phosphorylation. A similar pattern for protein kinase B phosphorylation was observed, upstream from S6K1. The S6K1 pathway was stimulated to the same extent in the EF and DF chicks, which indicates that post-hatching starvation did not increase S6K1 activation. It is concluded that muscle S6K1 is activated as soon as food is available without improvement in the response of the S6K1 pathway after post-hatching starvation.

Keywords

ChicksNeonatal feedingp70 S6 kinase activationSkeletal muscle
Type
Research Article
Information
British Journal of Nutrition , Volume 90 , Issue 6 , December 2003 , pp. 1023 - 1029
Copyright
Copyright © The Nutrition Society 2003

References

Agote, M, Goya, L, Ramos, S, et al. (2001) Glucose uptake and glucose transporters protein in skeletal muscle from undernourished rats Am J Physiol 281, E1101–E1109.Google ScholarPubMed
Ballou, LM, Luther, H & Thomas, G (1991) MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways Nature 349, 348–350.10.1038/349348a0CrossRefGoogle ScholarPubMed
Bigot, K, Mignon-Grasteau, S Picard, M & Tesseraud, S (2003 a) Effects of delayed food intake on body, intestine, and muscle development in neonate broilers Poult Sci 82, 781–788.Google Scholar
Bigot, K, Taouis, M & Tesseraud, S, (2003 b) Refeeding and insulin regulate S6K1 in chicken skeletal muscles. J Nutr 133, 369–373.10.1093/jn/133.2.369CrossRefGoogle ScholarPubMed
Bigot, K, Tesseraud, S, Taouis, M & Picard, M (2001) Alimentation néonatale et développement précoce du poulet de chair (Neonatale food and the early development of table fowl). INRA Prod Anim 14, 219–230.10.20870/productions-animales.2001.14.4.3743CrossRefGoogle Scholar
Bliss, CR & Sharp, GW (1994) Development of glucose responsiveness from the fetal to the adult B-cell In sulin Secretion and Pancreatic B-cell Research, pp. 69–76 [Flatt, PR and Lenzen, S, editors]. Whitstable, Kent, UK: Eldred Smith-Gordon.Google Scholar
Burgering, BM & Coffer, PJ (1995) Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376, 599–602.10.1038/376599a0CrossRefGoogle ScholarPubMed
Chamblee, TN, Brake, JD, Schultz, CD & Thaxton, JP (1992) Yolk sac absorption and initiation of growth in broilers Poul Sci 71, 1811–1816.10.3382/ps.0711811CrossRefGoogle ScholarPubMed
Davidson, RT, Arias, EB & Cartee, GD (2002) Calorie restriction increases muscle insulin action but not IRS-1-, IRS-2-, or phosphotyrosine-PI 3-kinase. Am J Physiol 282, E270–E276.Google ScholarPubMed
Davis, TA, Fiorotto, ML, Burrin, DG, et al. (2002) Stimulation of protein synthesis by both insulin and amino acids is unique to skeletal muscle in neonate pigs. Am J Physiol 282, E880–E890.Google Scholar
Davis, TA, Nguyen, HV, Suryawan, A, Bush, JA, Jefferson, LS & Kimball, SR (2000) Developmental changes in the feeding-induced stimulation of translation initiation in muscle of neonatal pigs. Am J Physiol 279, E1226–E1234.Google Scholar
Dean, DJ, Brozinick, JT, Cushman, SW & Cartee, GD (1998) Calorie restriction increases cell surface GLUT-4 in insulin-stimulated skeletal muscle Am J Physiol 275, E957–E964.Google ScholarPubMed
Dufner, A & Thomas, G (1999) Ribosomal S6 kinase signaling and the control of translation. Exp Cell Res 253, 100–109.10.1006/excr.1999.4683CrossRefGoogle ScholarPubMed
Dupont, J, Derouet, M, Simon, J & Taouis, M (1998) Effect of nutritional state on the formation of a complex involving insulin receptor IRS-1, the 52?kDa Src homology/collagen protein (Shc) isoform and phosphatidylinositol 3'-kinase activity. Biochem J 335, 293–300.Google Scholar
Egea, J, Espinet, C, Soler, RM, et al. (2001) Neuronal survival by neurotrophins requires calmodulin J Cell Biol 154, 585–597.10.1083/jcb.200101023CrossRefGoogle ScholarPubMed
Gazdag, AC, Dumke, CL, Kahn, CR & Cartee, GD (1999) Calorie restriction increases insulin-stimulated glucose transport in skeletal muscle from IRS-1 knockout mice. Diabetes 48, 1930–1936.Google Scholar
Halevy, O, Geyra, A, Barak, M, Uni, Z & Sklan, D, (2000) Early posthatching starvation decreases satellite cell proliferation and skeletal muscle growth in chicks J Nutr 130, 858–864.10.1093/jn/130.4.858CrossRefGoogle ScholarPubMed
Kawasome, H, Papst, P, Webb, S, et al. (1998) Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity Proc Natl Acad Sci USA 95, 5033–5038.10.1073/pnas.95.9.5033CrossRefGoogle ScholarPubMed
Kimball, SR, Farrell, PA, Nguyen, HV, Jefferson, LS & Davis, TA (2002) Developmental decline in components of signal transduction pathways regulating protein synthesis in pig muscle. Am J Physiol 282, E585–E592.Google Scholar
Kimball, SR & Jefferson, LS (2002) Control of protein synthesis by amino acid availability Curr Opin Clin Nutr Metab Care 5, 63–67.CrossRefGoogle ScholarPubMed
Long, W, Saffer, L, Wei, L & Barrett, EJ (2000) Amino acids regulate skeletal muscle PHAS-1 and S6K1 phosphorylation independently of insulin. Am J Physiol 279, E301–E306.Google Scholar
Mozdziak, PE, Evans, JJ & McCoy, DW (2002) Early posthatch starvation induces myonuclear apoptosis in chickens. J Nutr 132, 901–903.10.1093/jn/132.5.901Google Scholar
Murakami, H, Akiba, Y & Horiguchi, M (1992) Growth and utilisation of nutrients in newly-hatched chicks with or without removal of residual yolk Growth Dev Aging 56, 75–84.Google ScholarPubMed
Muramatsu, T (1990) Nutrition and whole-body protein turnover in the chicken in relation to mammalian species. Nutr Res Rev 3, 211–228.Google Scholar
Noy, Y & Sklan, D (1999) Different types of early feeding and performance in chicks and poults J Appl Poult Res 8, 16–24.10.1093/japr/8.1.16CrossRefGoogle Scholar
Ozanne, SE, Nave, BT, Wang, CL, Shepherd, PR, Prins, J & Smith, GD (1997) Poor fetal nutrition causes long-term changes in expression of insulin signaling components in adipocytes Am J Physiol 273, E46–E51.Google ScholarPubMed
Ozanne, SE, Wang, CL, Coleman, N & Smith, GD (1996) Altered muscle insulin sensitivity in the male offspring of protein-malnourished rats Am J Physiol 271, E1128–E1134.Google Scholar
Peyrollier, K, Hajduch, E, Blair, AS, Hyde, R & Hundal, HS (2000) L-leucine availability regulates phosphatidylinositol 3-kinase, S6K1 and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of system A amino acid transport. Biochem J 350, 361–368.Google Scholar
Proud, CG (2002) Regulation of mammalian translation factors by nutrients Eur J Biochem 269, 5338–5349.CrossRefGoogle ScholarPubMed
Ruffier, L, Crochet, S & Rideau, N (1998) Insulin release by islets of Langerhans isolated from dorsal and ventral lobes of chicken pancreas. Ann NY Acad Sci 839, 553–555.10.1111/j.1749-6632.1998.tb10870.xCrossRefGoogle ScholarPubMed
Shah, OJ, Anthony, JC, Kimball, SR & Jefferson, LS (2000) 4E-BP1.and S6K1: translational integration sites for nutritional and hormonal information in muscle. Am J Physiol 279, E715–E729.Google ScholarPubMed
Simon, J (1989) Chicken as a useful species for the comprehension of insulin action. Crit Rev Poult Biol 2, 121–148.Google Scholar
Stephens, LR, Anderson, KE & Hawkins, PT, (2001) Src family kinases mediate receptor-stimulated, phosphoinositide 3-kinase-dependent, tyrosine phosphorylation of dual adaptator for phosphotyrosine and 3-phosphoinositides-1 in endothelial and B cell lines. J Biol Chem 276, 42767–42773.CrossRefGoogle Scholar
Suryawan, A, Nguyen, HV, Bush, JA & Davis, TA (2001) Developmental changes in the feeding-induced activation of the insulin-signaling pathway in neonatal pigs. Am J Physiol 281, E908–E915.Google Scholar
Svanberg, E, Jefferson, LS, Lundholm, K & Kimball, SR (1997) Postprandial stimulation of muscle protein synthesis is independent of changes in insulin. Am J Physiol 271, E841–E847.Google Scholar
Taouis, M, Derouet, M, Chevalier, B & Simon, J (1993) Corticosterone effect on insulin receptor number and kinase activity in chicken muscle and liver Gen Comp Endocrinol 89, 167–175.10.1006/gcen.1993.1020Google Scholar
Weng, QP, Andrabi, K, Kozlowski, MT, Grove, JR & Avruch, J (1995) Multiple independent inputs required for activation of the p70 S6 kinase. Mol Cell Biol 15, 2333–2340.10.1128/MCB.15.5.2333Google Scholar