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Conjugated linoleic acid decreases fat accretion in pigs: evaluation by dual-energy X-ray absorptiometry

Published online by Cambridge University Press:  09 March 2007

Ewa Ostrowska ,
Danny Suster ,
Morley Muralitharan ,
Reg F. Cross ,
Brian J. Leury ,
Dale E. Bauman  and
Frank R. Dunshea
Ewa Ostrowska
Affiliation:
Agriculture Victoria, Victorian Institute of Animal Science, 600 Sneydes Road, Werribee, VIC 3030, Australia
Danny Suster
Affiliation:
Agriculture Victoria, Victorian Institute of Animal Science, 600 Sneydes Road, Werribee, VIC 3030, Australia
Morley Muralitharan
Affiliation:
Deakin University, Geelong, Victoria, Australia
Reg F. Cross
Affiliation:
Swinburne University of Technology, Hawthorn, VIC 3122, Australia
Brian J. Leury
Affiliation:
The University of Melbourne, Melbourne, 3010, Australia
Dale E. Bauman
Affiliation:
Cornell University, Ithaca, NY 14853, USA
Frank R. Dunshea*
Affiliation:
Agriculture Victoria, Victorian Institute of Animal Science, 600 Sneydes Road, Werribee, VIC 3030, Australia
*
*Corresponding author: Associate Professor Frank R. Dunshea, fax +61 3 9 742 0400, email [email protected]
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Abstract

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Thirty female Large White × Landrace pigs (average weight 57·2 (SD 1·9) kg) were allocated to one of six dietary treatments containing 0, 1·25, 2·5, 5·0, 7·5 or 10·0 g 55 % conjugated linoleic acids (CLA) isomers (CLA-55)/kg diet and fed for 8 weeks. Each pig was scanned at 0, 28 and 56 d and again at post slaughter using dual-energy X-ray absorptiometry (DXA) to determine the temporal pattern of body composition responses. Values determined by DXA were adjusted using regression equations generated from validation experiments between chemically and DXA-predicted values. Overall, there was a significant linear reduction in fat content with the increasing levels of CLA in the diet (P=0·007, P=0·011, P=0·008 at week 4, week 8 and for the carcass, respectively). The greatest improvement was recorded at the early stages of CLA supplementation and for the highest dose of CLA (week 4, −19·2 % compared with week 8, −13·7 %). In the first 4 weeks of feeding CLA, pigs receiving 10 g CLA-55/kg diet deposited 93 g less fat/d than pigs fed basal diets (P=0·002) compared with only 6 g less fat than control animals in the final 4 weeks. Lean content and lean deposition rate were maximised at 5 and 2·5 g CLA-55/kg diet for the first 4 weeks (P=0·016) and the final 4 weeks of treatment (P=0·17), respectively. DXA estimates of bone mineral content and bone mineral density were not affected by CLA supplementation throughout the experiment. These data demonstrate that dietary CLA decreases body fat in a dose-dependent manner and that the response is greatest over the initial 4 weeks of treatment.

Keywords

Conjugated linoleic acidDual-energy X-ray absorptiometryBody compositionPig
Type
Research Article
Information
British Journal of Nutrition , Volume 89 , Issue 2 , February 2003 , pp. 219 - 229
Copyright
Copyright © The Nutrition Society 2003

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