Hostname: page-component-586b7cd67f-dlnhk Total loading time: 0 Render date: 2024-11-28T22:21:24.113Z Has data issue: false hasContentIssue false
  • English
  • Français

Circadian variation in fat concentration of breast-milk in a rural northern Thai population

Published online by Cambridge University Press:  09 March 2007

Dorothy A. Jackson ,
Stella M. Imong ,
A. Silprasert ,
S. Ruckphaopunt ,
M. W. Woolridge ,
J. D. Baum  and
K. Amatayakul
Dorothy A. Jackson
Affiliation:
Research Institute for Health Sciences, Chiang Mai University, P.O. Box 80 CMU, Chiang Mai 50002, Thailand
Stella M. Imong
Affiliation:
Research Institute for Health Sciences, Chiang Mai University, P.O. Box 80 CMU, Chiang Mai 50002, Thailand
A. Silprasert
Affiliation:
Research Institute for Health Sciences, Chiang Mai University, P.O. Box 80 CMU, Chiang Mai 50002, Thailand
S. Ruckphaopunt
Affiliation:
Research Institute for Health Sciences, Chiang Mai University, P.O. Box 80 CMU, Chiang Mai 50002, Thailand
M. W. Woolridge
Affiliation:
Department of Child Health, University of Bristol, St Michael's Hill, Bristol BS2 8BJ
J. D. Baum
Affiliation:
Department of Child Health, University of Bristol, St Michael's Hill, Bristol BS2 8BJ
K. Amatayakul
Affiliation:
Research Institute for Health Sciences, Chiang Mai University, P.O. Box 80 CMU, Chiang Mai 50002, Thailand
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Twenty-five northern Thai mothers, breast-feeding their infants on demand, were studied in their homes for 24 h. All breast-feeds were test-weighed and pre- and post-feed expressed breast-milk samples (0·5 ml) taken at each feed.

2. The fat concentration of milk taken during a feed showed significant circadian variation, with maximum values between 16.00 and 20.00 hours and minimum values between 04.00 and 08.00 hours. Fat concentration at the start and at the end of a feed also varied significantly over 24 h.

3. Multiple regression analysis showed that the most important predictor of fat concentration at a feed was the length of time elapsed since the previous feed – the longer this interval, the lower the subsequent fat concentration. Other significant predictors were the fat concentration at the end of the previous feed, and the milk intake at the previous and at the current feed.

4. Fat concentration declined between feeds in proportion to the length of time between feeds, but the decline was less between sleep feeds than between waking feeds. This would appear to be a reflection of the lower post-feed fat concentration and higher pre-feed fat concentration of sleep feeds compared with waking feeds, when other variables relating to feeding pattern are taken into account.

5. The larger the milk intake at a feed, the greater was the increase in fat concentration from the start to the end of the feed. The change in fat concentration was less in feeds taking place during the sleep period than in daytime feeds.

Type
Research Article
Information
British Journal of Nutrition , Volume 59 , Issue 3 , May 1988 , pp. 349 - 363
Copyright
Copyright © The Nutrition Society 1988

References

Armitage, P. (1983). Statistical Methods in Medical Research. Oxford: Blackwell Scientific Publications.Google Scholar
Brown, K. H., Black, R. E., Robertson, A. D., Aktar, N. A., Ahmed, G. & Becker, S. (1982). American Journal of Clinical Nutrition 35, 745–756.CrossRefGoogle Scholar
Bunner, D. L., VanderLaan, E. F. & VanderLaan, W. P. (1978). American Journal of Obstetrics and Gynecology 131, 250–252.CrossRefGoogle Scholar
Deem, H. E. (1931). Archives of Disease in Childhood 6, 53–61.CrossRefGoogle Scholar
Drewett, R. F. & Woolridge, M. W. (1981). Physiology and Behaviour 26, 327–329.CrossRefGoogle Scholar
Gross, B. A., Eastman, C. J., Bowen, K. M. & McElduff, A. (1979). Australian and New Zealand Journal of Obstetrics and Gynaecology 19, 150–153.CrossRefGoogle Scholar
Gunther, M. & Stainier, J. E. (1949). Lancet ii, 235–237.CrossRefGoogle Scholar
Hall, B. (1979). American Journal of Clinical Nutrition 32, 304–312.CrossRefGoogle Scholar
Hytten, F. E. (1954 a). British Medical Journal i, 179–182.Google Scholar
Hytten, F. E. (1954 b). British Medical Journal i, 176–179.Google Scholar
Jackson, D. A., Imong, S. M., Silprasert, A., Preunglumpoo, S., Leelapat, P., Yootabootr, Y., Amatayakul, K. & Baum, J. D. (1988). British Journal of Nutrition 59, 365–371.CrossRefGoogle Scholar
Jackson, D. A., Woolridge, M. W., Imong, S. M., McLeod, C. N., Yutabootr, Y., Wongsawat, L., Amatayakul, K. & Baum, J. D. (1987). Early Human Development 15, 295–306.CrossRefGoogle Scholar
Khin-Maung-Naing, , Tin-Tin-Oo, , Kywe-Thein, & Nwe-Nwe-Hlaing, (1980). American Journal of Clinical Nutrition 33, 2665–2668.CrossRefGoogle Scholar
Kon, S. K. & Mawson, E. H. (1950). Special Report Series of the Medical Research Council no. 269, pp. 18–24.Google Scholar
Lauber, E. & Reinhardt, M. (1979). American Journal of Clinical Nutrition 32, 1159–1173.CrossRefGoogle Scholar
Lucas, A., Gibbs, J. A. H., Lyster, R. L. J. & Baum, J. D. (1978). British Medical Journal i, 1018–1020.CrossRefGoogle Scholar
Neville, M. C., Keller, R. P., Seacat, J., Casey, C. E., Allen, J. C. & Archer, P. (1984). American Journal of Clinical Nutrition 40, 635–646.CrossRefGoogle Scholar
Neville, M. C. & Neifert, M. R. (1980). Lactation. New York and London: Plenum Press.Google Scholar
Nims, G., Macy, I. C., Brown, M. & Hunscher, H. A. (1932). American Journal of Diseases of Children 43, 828–844.CrossRefGoogle Scholar
Prentice, A., Prentice, A. M. & Whitehead, R. G. (1981 a). British Journal of Nutrition 45, 483–494.CrossRefGoogle Scholar
Prentice, A., Prentice, A. M. & Whitehead, R. G. (1981 b). British Journal of Nutrition 45, 495–503.CrossRefGoogle Scholar
Read, W. W. C., Lutz, P. G. & Tashjian, A. (1965). American Journal of Clinical Nutrition 17, 184–187.CrossRefGoogle Scholar
Sassin, J. F., Frantz, A. G., Weitzman, E. D. & Kapen, S. (1972). Science 177, 1205–1207.CrossRefGoogle Scholar
Silprasert, A., Dejsarai, W., Keawvichit, R. & Amatayakul, K. (1986). Human Nutrition: Clinical Nutrition 40C, 31–36.Google Scholar
Tabachnik, B. G. & Fidell, L. S. (1983). Using Multivariate Statistics. New York: Harper & Row.Google Scholar
Tyson, J. E., Friesen, H. G. & Anderson, M. S. (1973). In Hypothalamic–Hypophysiotropic Hormones, pp. 396–403 [Gual, C. and Rosenberg, E., editors]. Amsterdam: Excerpta Medica.Google Scholar
Williams, A. F., Akinkugbe, F. M. & Baum, J. D. (1986). Human Nutrition: Clinical Nutrition 39C, 193–202.Google Scholar