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Characterization of an antithrombotic peptide from α-casein in newborn plasma after milk ingestion

Published online by Cambridge University Press:  09 March 2007

Beathice Chabance ,
Pierre Jollès ,
Carmen Izquierdo ,
Elisabeth Mazoyer ,
Christine Francoual ,
Ludovic Drouet  and
Anne-Marie Fiat
Beathice Chabance
Affiliation:
CNRS URA 1188, Laboratoire des Protéines, Université de Paris V, 45 rue des Saints-Pères, F-75270 Paris Cedex 06, France
Pierre Jollès
Affiliation:
CNRS URA 1188, Laboratoire des Protéines, Université de Paris V, 45 rue des Saints-Pères, F-75270 Paris Cedex 06, France
Carmen Izquierdo
Affiliation:
CNRS URA 1188, Laboratoire des Protéines, Université de Paris V, 45 rue des Saints-Pères, F-75270 Paris Cedex 06, France
Elisabeth Mazoyer
Affiliation:
Institut des Vaisseaux et du Sang, Hospital Lariboisière, 8 rue Guy Patin, F-75010 Paris, France
Christine Francoual
Affiliation:
Hôpital Saint-Vincent de Paul, 74-82 avenue Denfert Rochereau, F-75674 Paris Cedex 14, France
Ludovic Drouet
Affiliation:
Institut des Vaisseaux et du Sang, Hospital Lariboisière, 8 rue Guy Patin, F-75010 Paris, France
Anne-Marie Fiat
Affiliation:
CNRS URA 1188, Laboratoire des Protéines, Université de Paris V, 45 rue des Saints-Pères, F-75270 Paris Cedex 06, France
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Abstract

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Bovine and human k-caseinoglycopeptides, two antithrombotic peptides derived from the corresponding k-caseins, were detected in physiologically active concentrations in the plasma of 5-d-old newborn infants after ingestion of cow's-milk-based formula or human milk respectively. It is suggested that these two bioactive peptides are released from milk proteins during digestion.

Keywords

CaseinAntithrombotic peptidesNewborn infants
Type
Antithrombic peptides from casein in newborn
Information
British Journal of Nutrition , Volume 73 , Issue 4 , April 1995 , pp. 583 - 590
Copyright
Copyright © The Nutrition Society 1995

References

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