Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-25T18:29:07.976Z Has data issue: false hasContentIssue false
  • English
  • Français

Cellulose and pectin alter intestinal β-glucuronidase (EC 3.2.1.31) in the rat

Published online by Cambridge University Press:  09 March 2007

Rosemary Lindop ,
Clifford Tasman-Jones ,
Lindy L. Thomsen  and
Sum P. Lee
Rosemary Lindop
Affiliation:
Department of Medicine, University of Auckland, Private Bag, Auckland, New Zealand
Clifford Tasman-Jones
Affiliation:
Department of Medicine, University of Auckland, Private Bag, Auckland, New Zealand
Lindy L. Thomsen
Affiliation:
Department of Medicine, University of Auckland, Private Bag, Auckland, New Zealand
Sum P. Lee
Affiliation:
Department of Medicine, University of Auckland, Private Bag, Auckland, New Zealand
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Groups of rats were given a fibre-free diet containing none or one of the three fibre components: pectin, cellulose or galactomannan.

2. After feeding for 16 weeks, total protein level and β-glucuronidase (EC 3.2.1.31) activity in the contents and mucosa of jejunum and ileum, and in the contents only of the caecum, were determined.

3. The pectin supplement reduced protein concentration in jejunal contents while cellulose reduced protein concentration in the ileal and caecal contents.

4. β-Glucuronidase activity of caecal contents was significantly reduced in both the pectin- and cellulose-fed groups.

5. Cellulose affected the β-glucuronidase activity of both the ileal contents while pectin reduced the β-glucuronidase of the ileal but not the jejunal contents.

6. Dietary fibre components did not significantly affect jejunal or ileal mucosal β-glucuronidase activity.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 54 , Issue 1 , July 1985 , pp. 21 - 26
Copyright
Copyright © The Nutrition Society 1985

References

Armstrong, B. & Doll, R. (1975). International Journal of Cancer 15, 617–631.CrossRefGoogle Scholar
Bauer, H. G., Asp, N. G., Oste, R., Dahlqvist, A. & Fredlund, P. E. (1979). Cancer Research 39, 3752–3756.Google Scholar
Bueno, L., Praddaude, F., Fioramonti, J. & Ruckesbush, Y. (1981). Gastroenterology 80, 701–707.CrossRefGoogle Scholar
Celik, C., Lewis, D. A. & Mittleman, A. (1983). Journal of Surgical Oncology 24, 209–211.CrossRefGoogle Scholar
Clapp, N. K., Barnes, D. S., Scott, D. A., Oberst, D. L. & Berry, S. C. (1980). Proceedings of the American Association for Cancer Research and American Society of Clinical Oncology 21 (Abstr. 483), 121.Google Scholar
Freeman, H. J., Spiller, G. A. & Young, S. K. (1978). Cancer Research 38, 2912–2917.Google Scholar
Goldin, B. R., Dwyer, J., Gorbach, S. L., Gordon, W. & Swenson, L. (1978). American Journal of Clinical Nutrition 31, S136–S140.CrossRefGoogle Scholar
Goldin, B. R. & Gorbach, S. L. (1976). Journal of the National Cancer Institute, Washington 57, 371–375.CrossRefGoogle Scholar
Goldin, B. R. & Gorbach, S. L. (1979). In Advances in Nutritional Research, vol. 2, pp. 129–148 [Draper, H. H., editor]. New York: Plenum Press.CrossRefGoogle Scholar
Gorbach, S. L., Plaut, A. G., Nahas, L., Weinstein, L., Spanknebel, G. & Levitan, R. (1967). Gastroenterology 53, 856–867.CrossRefGoogle Scholar
Holloway, W. D., Tasman-Jones, C. & Bell, E. (1980). American Journal of Clinical Nutrition 33, 260–263.CrossRefGoogle Scholar
Holloway, W. D., Tasman-Jones, C. & Lee, S. P. (1978). American Journal of Clinical Nutrition 31, 927–930.CrossRefGoogle Scholar
Holloway, W. D., Tasman-Jones, C. & Maher, C. (1983). American Journal of Clinical Nutrition 37, 253–255.CrossRefGoogle Scholar
Indira, M., Vijayammal, P. L., Menon, P. V. G. & Kurup, P. A. (1980). Cancer 46, 2430–2432.3.0.CO;2-Q>CrossRefGoogle Scholar
Markwell, M. A. K., Haas, S. M., Bieber, L. L. & Tolbert, N. E. (1978). Analytical Biochemistry 87, 206–210.CrossRefGoogle Scholar
Reddy, B. S., Mangat, S., Weisburger, J. H. & Wynder, E. L. (1977). Cancer Research 37, 3533–3536.Google Scholar
Reddy, B. S., Narisawa, T., Vukusich, D., Weisburger, J. H. & Wynder, E. L. (1976). Proceedings of the Society of Experimental Biology and Medicine 151, 237–239.CrossRefGoogle Scholar
Roberton, A. M., Lee, S. P., Lindop, R., Stanley, R. A., Thomsen, L. & Tasman-Jones, C. (1982). Cancer Research 42, 5165–5166.Google Scholar