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Calcium solubilization and retention in the gastrointestinal tract in chicks (Gallus domesticus) as a function of gastric acid secretion inhibition and of calcium carbonate particle size

Published online by Cambridge University Press:  09 March 2007

F. Guinotte ,
J. Gautron ,
Y. Nys  and
A. Soumarmon
F. Guinotte
Affiliation:
Station de Recherches Avicoles, INRA Centre de Tours, 37380 Nouzilly, France
J. Gautron
Affiliation:
Station de Recherches Avicoles, INRA Centre de Tours, 37380 Nouzilly, France
Y. Nys
Affiliation:
Station de Recherches Avicoles, INRA Centre de Tours, 37380 Nouzilly, France
A. Soumarmon
Affiliation:
Inserm Unité 10, Hôpital Bichat, 170 boulevard Ney, 75877 Paris Cedex 18, France
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Abstract

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In chicks, immature pullets and laying hens, the inhibition of gastric acid secretion by omeprazole, an H+,K+-transporting ATPase (EC 3.6.1.36) inhibitor, greatly increased proventricular and gizzard pH values. Consequently, gizzard soluble Ca concentration deceased and the insoluble Ca fraction increased. Inhibition of acid secretion increased duodenal pH values in immature pullets and laying hens but not in chicks. Duodenal soluble and ionic Ca concentrations were lowered by gastric acid inhibition in chicks and to a larger extent in immature pullets and laying hens. The use of Ca of coarse particle size increased the gizzard insoluble Ca fraction in chicks and pullets. However, it did not influence its soluble Ca fraction in chicks but tended to reinforce the negative effect of omeprazole on soluble Ca in the gizzard and duodenum of chicks and laying hens. Coarse particles of Ca led to an increase in gizzard and duodenal soluble Ca at the end of eggshell calcification in laying hens. An enhancement in the level of Ca in the diet from 10 to 36 g/kg increased gizzard soluble Ca and duodenal soluble and ionic Ca concentrations in immature and adult hens. Intestinal Ca retention and bone mineralization was unaffected by gastric acid inhibition in chicks but were largely diminished by the use of coarse particles of Ca. Gastric acid inhibition was associated in laying hens with decreased Ca retention to a small extent and with reduced eggshell quality. These observations confirm that gastric acid secretion is of importance for CaCO, solubilization but question its role as a prerequisite for intestinal Ca retention in chicks and even in hens fed on a high Ca diet.

Keywords

CalciumParticle sizeOmeprazoleGastric acid secretionChicken
Type
Research Article
Information
British Journal of Nutrition , Volume 73 , Issue 1 , January 1995 , pp. 125 - 139
Copyright
Copyright © The Nutrition Society 1995

References

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