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Brain in human nutrition and variant Creutzfeldt–Jakob disease risk (vCJD): detection of brain in retail liver sausages using cholesterol and neuron specific enolase (NSE) as markers

Published online by Cambridge University Press:  09 March 2007

E. Lücker*
Affiliation:
Institute of Food Hygiene, University of Leipzig, An der Tierkliniken 35, 04103 Leipzig, Germany
S. Horlacher
Affiliation:
Institute of Veterinary Food Science, Justus-Liebig University, Giessen, Frankfurter St 92, 35392 Giessen, Germany
E. Eigenbrodt
Affiliation:
Institute of Biochemistry and Endocrinology, Justus-Liebig University, Giessen, Frankfurter St 100, 35392 Giessen, Germany
*
*Corresponding author: Dr E. Lücker, fax +49 341 97 3 82 49, email [email protected]
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Abstract

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Type
Research Article
Copyright
Copyright © The Nutrition Society 2001

References

Anderson, RM, Donelly, CA, Ferguson, NM, Woolhouse, MEJ, Watt, CJ, Udy, HJ, MaWhinney, S, Dunstan, SP, Southwood, TRE, Wilesmith, JW, Ryan, JBM, Hoinville, LJ, Hillerton, JE, Austin, AR & Wells, GAH (1996) Transmission dynamics and epidemiology of BSE in British cattle. Nature 382, 779788.CrossRefGoogle ScholarPubMed
Anonymous (1995) Colorimetric method for the determination of cholesterol in foodstuffs and other material. Roche/Boehringer, Mannheim, Germany no. 139 050.Google Scholar
BgVV, , Bundesinstitut für gesundheitlichen Verbraucherschutz und Veterinärmedizin (Federal Institute of Health, Consumer Protection and Veterinary Medicine) (1992) Bestimmung des Cholesteringehaltes in Eiern und Eiprodukten. Enzymatisches Verfahren. In Amtliche Sammlung von Untersuchungsverfahren nach § 35 LMBG, L-05.00-17. Berlin: Beuth Verlag.Google Scholar
Dixon, WJ (1993) BMDP Statistical Software Manual. Berkley: University of California Press.Google Scholar
Gajdusek, DC (1977) Unconventional viruses and the origin and disappearance of kuru. Science 197, 943960.Google Scholar
German Food Code (2000) Guiding principles for meat and meat products. Bundesanzeiger, pp. 47–148. Köln.Google Scholar
Hildebrandt, G & Kleer, J (1998) Kochwurst, gegarte Stückware und Schmalz. Fleischwirtschaft 78, 11201129.Google Scholar
Kato, K, Ishiguro, Y, Suzuki, J, Ito, A & Semba, R (1982) Distribution of nervous system-specific forms of enolase in peripheral tissues. Brain Research 237, 441448.Google Scholar
Laemmli, UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680685.Google Scholar
Lücker, E, Eigenbrodt, E, Wenisch, S, Failing, K, Leiser, R & Bülte, M (1999) Development of an integrated procedure for the detection of central nervous tissue in meat products using cholesterol and neuron-specific enolase as markers. Journal of Food Protection 62(3), 268276.Google Scholar
Lücker, E, Eigenbrodt, E, Wenisch, S, Leiser, R & Bülte, M (2000) Identification of central nervous system tissue in retail meat products. Journal of Food Protection 63(2), 258263.CrossRefGoogle ScholarPubMed
Marangos, PJ, Schmechel, D, Parma, AM, Clark, RL & Goodwin, FK (1979) Measurement of neuron-specific (NSE) and non-neuronal (NNE) isoenzymes of enolase in rat, monkey and human nervous tissue. Journal of Neurochemistry 33, 319329.Google Scholar
Röschlau, P, Bernt, E & Gruber, W (1974) Methoden der enzymatischen Analyse, 3rd edn., vol. 2, pp. 1938–1941 [Bergmeyer, HU, editor]. Weinheim: Verlag Chemie.Google Scholar
Runquist, M, Parmryd, I, Thelin, A, Chojnacki, T & Dallner, G (1995) Distribution of branch point prenyltransferases in regions of bovine brain. Journal of Neurochemistry 65, 22992306.Google Scholar
SSC, Scientific Steering Committee (1998) Listing of specified risk materials: a scheme for assessing relative risks to man – Opinion of the Scientific Steering Committee adopted on 9 December 1997. http://europa.eu.int/comm/dg24/health/sc/ssc/outcome_en.html.Google Scholar
Seiferle, E (1992) Lehrbuch der Anatomie der Haustiere, 3rd edn., vol. 4, pp. 27–59 [Nickel, R, Schummer, A and Seiferle, E, editors]. Berlin: Paul Parey Verlag.Google Scholar
Souci, SW, Fachmann, W & Kraut, H (1994) Food Composition and Nutrition Tables, 5th edn., Stuttgart: Medpharm Scientific PublishersGoogle Scholar
UK Government (1989) The bovine offal (prohibition) regulations. United Kingdom SI no. 2061.Google Scholar
Will, RG, Ironside, JW, Zeidler, M, Cousens, SN, Estibeiro, K, Alperovitch, A, Poser, S, Pocchiari, M & Hofman, A (1996) A new variant of Creutzfeldt–Jakob disease in the UK. Lancet 347, 921925.CrossRefGoogle ScholarPubMed