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Biomonitoring the intake of garlic via urinary excretion of allyl mercapturic acid

Published online by Cambridge University Press:  09 March 2007

H. Verhagen*
Affiliation:
TNO Voeding, P.O. Box 360, Zeist, 3700 AJ, The Netherlands
G. J. Hageman
Affiliation:
University of Maastricht, P.O. Box 616, 6200-MD, Maastricht, The Netherlands
A-L. Rauma
Affiliation:
University of Joensuu, P.O. Box 55, Joensuu, FIN-57101, Finland
G. Versluis-de Haan
Affiliation:
TNO Voeding, P.O. Box 360, Zeist, 3700 AJ, The Netherlands
M. H. M. van Herwijnen
Affiliation:
University of Maastricht, P.O. Box 616, 6200-MD, Maastricht, The Netherlands
J. de Groot
Affiliation:
University of Maastricht, P.O. Box 616, 6200-MD, Maastricht, The Netherlands
R. Törrönen
Affiliation:
University of Kuopio, P.O. Box 1627, Kuopio, FIN-70211, Finland
H. Mykkänen
Affiliation:
University of Kuopio, P.O. Box 1627, Kuopio, FIN-70211, Finland
*
*Corresponding author: Dr H. Verhagen: Unilever Research Vlaardingen, Unilever Health Institute, P.O. Box 114, 3130 AC, Vlaardingen, The Netherlands, fax +31 10 460 5993, email [email protected]
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Abstract

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Type
Research Article
Copyright
Copyright © The Nutrition Society 2001

References

Anonymous 1997 Food, Nutrition and the Prevention of Cancer: a Global PerspectiveWorld Cancer Research Fund/American Institute for Cancer Research.Google Scholar
Bartzatt, R, Blum, D & Nagel, D (1992) Isolation of garlic-derived sulfur compounds in urine. Analytical Letters 25, 12171224.CrossRefGoogle Scholar
Block, E (1992) The organosulfur chemistry of the genus Allium – Implications for the organic chemistry of sulfur. Angewandte Chemie International Edition in English 31, 11351179.CrossRefGoogle Scholar
Carson, JF (1987) Chemistry and biological properties of onions and garlic. Food Reviews International 3, 71103.CrossRefGoogle Scholar
De Rooij, BM, Boogaard, PJ, Commandeur, JNM, Van Sittert, NJ & Vermeulen, NPE (1997) Allyl mercapturic acid as urinary biomarker of human exposure to allyl chloride. Occupational and Environmental Medicine 54, 653661.CrossRefGoogle ScholarPubMed
De Rooij, BM, Boogaard, PJ, Rijksen, DA, Commandeur, JN & Vermeulen, NP (1996) Urinary excretion of N-acetyl-S-allyl-L-cysteine upon garlic consumption by human volunteersy. Archives of Toxicology 70, 635639.CrossRefGoogle Scholar
Ernst, E (1997) Can Allium vegetables prevent cancer? Phytomedicine 4, 7983.CrossRefGoogle ScholarPubMed
Jandke, J & Spiteller, G (1987) Unusual conjugates in biological profiles originating from consumption of onions and garlic. Journal of Chromatography 421, 18.CrossRefGoogle ScholarPubMed
Lau, BHS, Tadi, PP & Tosk, JM (1990) Allium sativum (garlic) and cancer prevention. Nutrition Research 10, 937948.CrossRefGoogle Scholar
Minami, T, Boku, T, Inada, K, Morita, M & Okazaki, Y (1989) Odour components of human breath after the ingestion of grated raw garlic. Journal of Food Science 54, 763765.CrossRefGoogle Scholar
Mütsch-Eckner, M, Sticher, O & Meier, B (1992) Reversed-phase high-performance liquid chromatography of S-alk(en)yl-l-cysteine derivatives in Allium sativum including the determination of (+)-S-allyl-l-cysteine and gamma-L-glutamyl-S-trans-l-propenyl-L-cysteine. Journal of Chromatography 625, 183190.CrossRefGoogle Scholar
Orekhov, AN & Grunwald, J (1997) Effects of garlic on atherosclerosis. Nutrition 13, 656663.CrossRefGoogle ScholarPubMed
Rauma, AL, Törrönen, R, Hänninen, O, Verhagen, H & Mykkänen, H (1995) Antioxidant status in long-term adherents to a strict uncooked vegan diet. American Journal of Clinical Nutrition 62, 12211227.CrossRefGoogle ScholarPubMed
Van Poppel, G, Verhagen, H & Heinzow, B (1997) Biomarkers in epidemiological and toxicological nutrition research. In Food Chemical Risk Analysis, pp. 87108[Tennant, D, editor]. London: Chapman and hall.CrossRefGoogle Scholar
Verhagen, H, Rompelberg, CJM, Strube, M, Van Poppel, G & Van Bladeren, PJ (1997) Cancer prevention by dietary constituents in toxicological perspective. Journal of Environment Pathology Toxicology and Oncology 16, 343360.Google Scholar