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Allantoin excretion in the rat

Published online by Cambridge University Press:  09 March 2007

Nelly Pak
Affiliation:
Basic Nutrition Unit, Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile
G. Donoso
Affiliation:
Basic Nutrition Unit, Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile
Marfa A. Tagle
Affiliation:
Basic Nutrition Unit, Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile
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Abstract

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1. Allantoin excretion was determined in forty-four rats; twenty-four rats were 21 d old and twenty were 90 d old. The animals received ad lib. for 11 d diets that contained varying amounts of protein from casein and from gluten. Urinary allantoin excretion was determined during the last 3 d of the period.

2. The amount of allantoin excreted in both young and adult animals was independent of the diet consumed and was related to metabolic weight (W in kg0·73) and rate of gain in body-weight (ΔW in g/d), also to body nitrogen content (N in g0·73) and rate of gain in body N (ΔN in mg/d), according to the equations allantoin (mg/d) = 60·54 W0·73 + 2·12ΔW, and allantoin (mg/d) = 5·45 N0·73 + 0·071ΔN.

Type
General Nutrition
Copyright
Copyright © The Nutrition Society 1973

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