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Albumin metabolism in fasting, obese subjects

Published online by Cambridge University Press:  09 March 2007

Fiona C. Ballantyne ,
J. Smith  and
A. Fleck
Fiona C. Ballantyne
Affiliation:
University Departments of Pathological Biochemistry and Medicine, Royal Infirmary, Castle Street, Glasgow
J. Smith
Affiliation:
University Departments of Pathological Biochemistry and Medicine, Royal Infirmary, Castle Street, Glasgow
A. Fleck
Affiliation:
University Departments of Pathological Biochemistry and Medicine, Royal Infirmary, Castle Street, Glasgow
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Abstract

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1. Eleven obese subjects fasted for 24 d, by which time their serum albumin concentration had fallen significantly. 125I-labelled albumin was injected on day 7 of fasting to allow study of albumin metabolism.

2. Although no significant alteration occurred in either the intravascular content or the absolute catabolic rate of albumin between days 7 and 24 of fasting, the mean values for both content and catabolic rate were significantly lower than values determined in eight normal subjects.

3. A corresponding fall occurred in the absolute ‘synthesis+transfer’rate.

Type
Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 30 , Issue 3 , November 1973 , pp. 585 - 592
Copyright
Copyright © The Nutrition Society 1973

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