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Absorption of L-histidine and glucose from the jejunum segment of the pig and its diurnal fluctuation

Published online by Cambridge University Press:  09 March 2007

S. Furuya  and
S. Takahashi
S. Furuya
Affiliation:
Department of Nutrition, National Institute of Animal Industry, Chiba-Shi 280, Japan
S. Takahashi
Affiliation:
Department of Nutrition, National Institute of Animal Industry, Chiba-Shi 280, Japan
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Abstract

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1. Flow rate of digesta and its components in the upper jejunum, and the absorption of L-histidine and glucose from the jejunum segment were measured in pigs fitted with three simple cannulas. The pigs were fed once daily at 08.30 hours.

2. A maximum flow of digesta was obtained in the period 10.00–10.30 hours; the flow rate decreased with time after feeding, reaching a minimum in the period 22.00–22.30 hours.

3. The absorption rate for L-histidine and glucose increased in a hyperbolic manner with increasing concentrations of infused test material, which ranged from 2.5 to 20 g/l for each material.

4. L-histidine and glucose were absorbed nearly independently when perfused in combination. The absorption rates for glucose were significantly (P < 0.01) greater than the corresponding rates for L-histidine at each concentration of infusate.

5. The absorption of both L-histidine and glucose expressed as a percentage of the amounts in the perfusate decreased with increasing flow rate of perfusate, from 400 to 800 ml/h. The increase in flow rate from 400 to 800 ml/h was associated with a 20% increase in L-histidine absorption rate; there was a 30% increase in glucose absorption rate when the flow rate was increased to 600 ml/h, but no further increase at 800 ml/h.

6. The absorption of both L-histidine and glucose decreased with time after feeding; the absorption rates for L-histidine and glucose measured for the period 10.00–10.30 hours were 126 and 133%, respectively, of those measured for the period 22.00–22.30 hours.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 34 , Issue 2 , September 1975 , pp. 267 - 277
Copyright
Copyright © The Nutrition Society 1975

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