Historians of archaeology have noted that prehistoric stone artefacts were first identified as such during the seventeenth century, and a great deal has been written about the formulation of the idea of a Stone Age in the nineteenth century. Much less attention has been devoted to the study of prehistoric artefacts during the eighteenth century. Yet it was during this time that researchers first began systematically to collect, classify and interpret the cultural and historical meaning of these objects as archaeological specimens rather than geological specimens. These investigations were conducted within the broader context of eighteenth-century antiquarianism and natural history. As a result, they offer an opportunity to trace the interrelationships that existed between the natural sciences and the science of prehistoric archaeology, which demonstrates that geological theories of the history of the earth, ethnographic observations of ‘savage peoples’ and natural history museums all played important roles in the interpretation of prehistoric stone implements during the eighteenth century.