Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-26T04:12:33.975Z Has data issue: false hasContentIssue false

How Deep is the Skin? The Geneticization of Race and Medicine

Published online by Cambridge University Press:  01 June 2007

Gísli Pálsson
Affiliation:
Department of Anthropology, University of Iceland, 101 Reykjavik, Iceland E-mail: [email protected]
Get access

Abstract

‘Racial’ or ‘ethnic’ drugs, a product of the new genetics and its mapping of genomes and populations, are now being developed and manufactured on a large scale. This article focuses on the conceptualization and identification of genetic signatures at the population level, many of which, I argue, evoke the ancient and quite common folk idiom of bodily inscription—in particular, fingerprints and birthmarks. The current geneticization of ‘colour’ and the biosociality engendered by it, I suggest, invite critical rethinking of the concept of insular populations and the distinction between bodily surface and deep structures (phenotype and genotype). While the new genetics has shifted the conceptual ground for discussions of human variation, moving away from phenotypic traits such as markings of the skin, drawing attention to what some molecular biologists refer to as the ‘universe within’, the notion of racial difference is repeatedly reinvented along familiar lines, under the banner of populations studies. I argue that, although human variation is both a legitimate and important subject in its own right and some approaches to variation do a better job than others, researchers need to be attentive to their assumptions about sampling. Circularity and subjectivity seem to be inevitable parts of the exploration of human diversity, and sampling cannot take place without a subjective, pragmatic judgment about how to proceed.

Type
Articles
Copyright
Copyright © London School of Economics and Political Science 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Baylis, F. (2003). Black as me: Narrative identity. Developing World Bioethics, 3, 142150.Google Scholar
Biddle, J. (2001). Inscribing identity: Skin as country in the central desert. In Ahmed, S. & Stacey, J. (Eds), Thinking through the skin. London: Routledge.Google Scholar
Bird-David, N. (2004). Illness-images and joined beings: A critical/Nayaka perspective on intercorporeality. Social Anthropology, 12, 325339.Google Scholar
Boas, F. (1940). Race, language and culture. New York: Macmillan.Google Scholar
Brookes, A.J. (2001). Rethinking genetic strategies to study complex diseases. Trends in Molecular Medicine, 7, 512516.Google Scholar
Caspari, R. (2003). From types to populations: A century of race, physical anthropology, and the American Anthropological Association. American Anthropologist, 105, 6576.Google Scholar
Cavalli-Sforza, L.L. (2005). The Human Genome Diversity Project: Past, present and future. Nature Reviews/ Genetics, 6(April), 333340.Google Scholar
Cole, S. (1999). What counts for identity? The historical origins of the methodology of latent fingerprint identification. Science in Context, 12, 139172.Google Scholar
Collins, F.S. (2004). What we do and don’t know about ‘race’, ‘ethnicity’, genetics and health at the dawn of the genome era. Nature Genetics Supplement, 36, S1315.Google Scholar
Connor, S. (2004). The book of skin. Ithaca, NY: Cornell University Press.Google Scholar
Epstein, R. (2002). Fingerprints meet Daubert: The myth of fingerprint ‘science’ is revealed. Southern California Law Review, 75, 605657.Google Scholar
Fanon, F. (1967). Black skin, white masks, trans. C.L. Markman. New York: Grove Press.Google Scholar
Galton, F. (1892). Finger prints. London: Macmillan.Google Scholar
Gannett, L., & Griesemer, J. (2004). The ABO blood groups: Mapping the history and geography of genes in Homo sapiens. In Rheinberger, H.-J. & Gaudillière, J.-P. (Eds), Classical genetics research and its legacy: The mapping cultures of twentieth-century genetics. London: Routledge.Google Scholar
Glick Schiller, N. (2005). Blood and belonging: Long-distance nationalism and the world beyond. In McKinnon, S. & Silverman, S. (Eds), Complexities: Beyond nature and nurture. Chicago: University of Chicago Press.Google Scholar
Gupta, A., & Ferguson, J. (1997). Beyond ‘culture’: Space, identity, and the politics of difference. In Gupta, A. & Ferguson, J. (Eds), Anthropological locations: Boundaries and grounds of a field science. Berkeley: University of California Press.Google Scholar
Hawthorne, N. (1959/1843). The birthmark. In The complete short stories of Nathaniel Hawthorne. New York: Doubleday.Google Scholar
Helgadottir, A., Manolescu, A., Helgason, A, Thorleifsson, G., Thorsteinsdottir, U., Gudbjartsson, D.F. et al. . (2005). A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nature Genetics, 38, 1315.Google Scholar
Jablonski, N.G. (2006). Skin: A natural history. Berkeley: University of California Press.Google Scholar
Kittles, R.A., & Weiss, K.M. (2003). Race, ancestry, and genes: Implications for defining disease risk. Annual Review in Genomics and Human Genetics, 4, 3367.Google Scholar
M’charek, A. (2005). The Human Genome Diversity Project: An ethnography of scientific practice. Cambridge: Cambridge University Press.Google Scholar
Pálsson, G., & Harðardóttir, K.E. (2002). For whom the cell tolls: Debates about biomedicine. Current Anthropology, 43, 271301.Google Scholar
Prosser, J. (2001). Skin memories. In Ahmed, S. & Stacey, J. (Eds), Thinking through the skin. London: Routledge.Google Scholar
Rabinow, P. (1996). Essays on the anthropology of reason. Princeton, NJ: Princeton University Press.Google Scholar
Reardon, J. (2005). Race to the finish: Identity and governance in an age of genomics. Princeton, NJ: Princeton University Press.Google Scholar
Risch, N., Burchard, E., Ziv, E., & Tang, H. (2002). Categorization of humans in biomedical research: Genes, race and disease. Genome Biology, 3, 112.Google Scholar
Rosenberg, N.A., Pritchard, J.K., Weber, J.L., Cann, H.M., Kidd, K.K., Zhivotovsky, L.A. et al. (2002). Genetic structure of human populations. Science, 298, 23812385.Google Scholar
Rosenberg, N.A., Mahajan, S., Ramachandran, S., Zhao, C., Pritchard, C.K., & Feldman, M.W. (2005). Clines, clusters, and the effect of study design on the inference of human population structure. PLoS Genetics, 1, 660671.Google Scholar
Serre, D., & Pääbo, S. (2004). Evidence for gradients of human genetic diversity within and among continents. Genome Research, 14, 16791685.Google Scholar
Stacey, J. (1997). Teratologies: A cultural study of cancer. London: Routledge.Google Scholar
Stevenson, I. (1997). Where reincarnation and biology intersect. Westport, CT: Praeger.Google Scholar
Tate, S.K., & Goldstein, D.B. (2004). Will tomorrow’s medicines work for everyone? Nature Genetics Supplement, 36, S34S42.Google Scholar
Templeton, A.R. (1999). Human races: A genetic and evolutionary perspective. American Anthropologist, 100, 632650.Google Scholar
Waldby, C. (2002). Biomedicine, tissue transfer and intercorporeality. Feminist Theory, 3, 239254.Google Scholar
Wright, S. (1969). Evolution and the genetics of populations, vol. II: The theory of gene frequencies. Chicago: University of Chicago Press.Google Scholar