This paper seeks to examine the feasibility of targeting cognitive therapy during early relapse, using a single case design. Gumley, White and Power (1999) offer a theoretical conceptualization of psychotic relapse based on Teasdale and Barnard's (1993) ICS model of depression. This conceptualization aims to provide a means for clinicians and patients to formulate the key psychological factors, which may be responsible for the initiation, acceleration and maintenance of relapse, thereby enabling these factors to be targeted should a relapse be indicated. The intervention received by a case illustrated in this paper is derived from the ICS conceptualization of relapse. The intervention has two stages: an initial engagement and formulation phase and, if required, a targeted cognitive therapy phase. All of the characteristics of traditional cognitive therapy are adhered to, including the use of structure, problem focus, agenda, a socratic style, and collaboration. The paper concludes that there is a need for further research to provide further evidence of the feasibility and efficacy of this approach.