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Predicting Therapy Outcome in Patients with Early and Late Obsessive-Compulsive Disorder (EOCD and LOCD)

Published online by Cambridge University Press:  02 October 2009

Judith Langner ,
Manuela Laws ,
Gisela Röper ,
Michael Zaudig ,
Walter Hauke  and
Christoph Piesbergen
Judith Langner
Affiliation:
Ludwig-Maximilians-Universität, Munich, Germany
Manuela Laws
Affiliation:
Ludwig-Maximilians-Universität, Munich, Germany
Gisela Röper*
Affiliation:
Ludwig-Maximilians-Universität, Munich, Germany
Michael Zaudig
Affiliation:
Psychosomatic Clinic, Windach, Germany
Walter Hauke
Affiliation:
Psychosomatic Clinic, Windach, Germany
Christoph Piesbergen
Affiliation:
Ludwig-Maximilians-Universität, Munich, Germany
*
Reprint requests to Gisela Roper, LMU-University of Munich, Department of Clinical Psychology, Leopoldstrasse 13, München 80802, Germany. E-mail: [email protected]
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Abstract

Background: Increasing attention has been given to subtyping OCD with respect to different clinical profiles, response to drug treatments, comorbidity and age of onset. There are a number of studies looking at predictors of treatment outcome in OCD, but so far not for OCD subtypes. Method: Prediction of outcome after cognitive-behavioural therapy was evaluated in 63 inpatients with early obsessive-compulsive disorder (EOCD ≤ 12 years of age) and 191 patients with late obsessive-compulsive disorder (LOCD > 15 years of age). Results: For EOCD patients factors predicting a good outcome included high motivation and high initial Y-BOCS scores. Factors associated with a bad outcome were higher age at assessment, a longer duration of psychiatric inpatient treatment before assessment and a low level of social functioning (BSS). For LOCD patients living in a stable relationship, high motivation and completing treatment predicted a favourable therapy outcome, while a low level of psychological functioning (BSS) and a longer duration of inpatient psychiatric treatment before assessment were associated with an undesirable therapy outcome. Conclusions: Subtyping OCD patients according to age of onset seems to be a promising avenue towards improving and developing more specified treatment programs.

Keywords

Obsessive-compulsive disorderpredictors for treatment outcomelate onsetearly onset
Type
Empirically Grounded Clinical Interventions
Information
Behavioural and Cognitive Psychotherapy , Volume 37 , Issue 5 , October 2009 , pp. 485 - 496
Copyright
Copyright © British Association for Behavioural and Cognitive Psychotherapies 2009

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