Twenty-two subjects diagnosed as having an occupationally related injury to the connective tissues, joints or muscles of the hands, arms, neck, shoulders or upper back were included in an experimental study which investigated the effectiveness of a cognitive-behavioural and movement-retraining program for reducing anxiety, depression, pain and disruption of activities by pain. Group and single case analyses indicated that the intervention program was associated with reductions in pain and the extent to which pain disrupted activities of daily living for some subjects, but program effects did not maintain over time.