Cognitive-behavioural (CB) therapy for internalising disorders in youth is discussed from both a procedural and empirical standpoint. A theoretical overview of CB treatment is provided, and the unique difficulties faced in the identification and treatment of internalising disorders are considered. With reference to specific internalising disorders (i.e., anxiety and depression), the present paper considers the differential application of CB strategies and the efficacy of treatment procedures. Issues relevant to CB treatment, including (a) flexibility in application, (b) developmental considerations, (c) treatment methodology, and (d) transportability, are discussed.