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Two compartmental models of EEG coherence and MRI biophysics

Published online by Cambridge University Press:  10 October 2000

R. W. Thatcher
Affiliation:
VA Medical Center, R&D – 151, Bay Pines, FL 33744 and Defense and Veterans Head Injury Program, Washington DC [email protected]
J. F. Gomez-Molina
Affiliation:
VA Medical Center, R&D – 151, Bay Pines, FL 33744 and Defense and Veterans Head Injury Program, Washington DC [email protected]
C. Biver
Affiliation:
VA Medical Center, R&D – 151, Bay Pines, FL 33744 and Defense and Veterans Head Injury Program, Washington DC [email protected]
D. North
Affiliation:
VA Medical Center, R&D – 151, Bay Pines, FL 33744 and Defense and Veterans Head Injury Program, Washington DC [email protected]
R. Curtin
Affiliation:
VA Medical Center, R&D – 151, Bay Pines, FL 33744 and Defense and Veterans Head Injury Program, Washington DC [email protected]
R. W. Walker
Affiliation:
VA Medical Center, R&D – 151, Bay Pines, FL 33744 and Defense and Veterans Head Injury Program, Washington DC [email protected]

Abstract

Studies have shown that as MRI T2 relaxation time lengthens there is a shift toward more unbound or “free-water” and less partitioning of the protein/lipid molecules per unit volume. A shift toward less water partitioning or lengthened MRI T2 relaxation time is linearly related to reduced high frequency EEG amplitude, reduced short distance EEG coherence, increased long distance EEG coherence, and reduced cognitive functioning (Thatcher et al. 1998a; 1998b).

Type
Brief Report
Copyright
© 2000 Cambridge University Press

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