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The romance of balancing selection versus the sober alternatives: Let the data rule

Published online by Cambridge University Press:  09 November 2006

John J. McGrath
John J. McGrath*
Affiliation:
Queensland Centre for Mental Health Research, University of Queensland, The Park Centre for Mental Health, Wacol, Queensland4076, Australia
*
[email protected]
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Abstract:

Schizophrenia has attracted more than its fair share of evolutionary-based theories. The theories involving balancing selection are based on the assumption that the incidence of schizophrenia is invariant across time and place. Modern epidemiology allows us to reject this dogmatic belief. Once variations in the genetic and epidemiological landscape of schizophrenia are acknowledged, more productive research models can be generated.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 29 , Issue 4 , August 2006 , pp. 417 - 418
Copyright
Copyright © Cambridge University Press 2006

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