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A rigorous approach for testing the constructionist hypotheses of brain function

Published online by Cambridge University Press:  23 May 2012

Gopikrishna Deshpande ,
K. Sathian ,
Xiaoping Hu  and
Joseph A. Buckhalt
Gopikrishna Deshpande
Affiliation:
Auburn University MRI Research Center, Department of Electrical and Computer Engineering, and Department of Psychology, Auburn University, Auburn, AL 36849. [email protected]://www.eng.auburn.edu/users/gzd0005/
K. Sathian
Affiliation:
Departments of Neurology, Rehabilitation Medicine, and Psychology, Emory University, and Atlanta VAMC Rehabilitation R&D Center of Excellence, Atlanta, GA 30322. [email protected]://neurology.emory.edu/Faculty/Sathian.htm
Xiaoping Hu
Affiliation:
Coulter Department of Biomedical Engineering at Georgia Institute of Technology, and Center for Systems Imaging, Emory University, Atlanta, GA 30322. [email protected]://www.bme.emory.edu/~xhu/
Joseph A. Buckhalt
Affiliation:
Department of Special Education, Rehabilitation and Counseling, College of Education, Auburn University, Auburn, AL 36849-5222. [email protected]://www.auburn.edu/~buckhja/
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Abstract

Although the target article provides strong evidence against the locationist view, evidence for the constructionist view is inconclusive, because co-activation of brain regions does not necessarily imply connectivity between them. We propose a rigorous approach wherein connectivity between co-activated regions is first modeled using exploratory Granger causality, and then confirmed using dynamic causal modeling or Bayesian modeling.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 35 , Issue 3 , June 2012 , pp. 148 - 149
Copyright
Copyright © Cambridge University Press 2012

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References

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