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The NGF superfamily of neurotrophins: Potential treatment for Alzheimer's and Parkinson's disease
Published online by Cambridge University Press: 04 February 2010
Abstract
Stein & Glasier suggest embryonic neural tissue grafts as a potential treatment strategy for Alzheimer's and Parkinson's disease. As an alternative, we suggest that the family of nerve growth factor-related neurotrophins and their trk (tyrosine kinase) receptors underlie cholinergic basal forebrain (CBF) and dopaminergic substantia nigra neuron degeneration in these diseases, respectively. Therefore, treatment approaches for these disorders could utilize neurotrophins.
- Type
- Open Peer Commentary
- Information
- Behavioral and Brain Sciences , Volume 18 , Issue 1: An International Journal of Current Research and Theory with Open Peer Commentary , March 1995 , pp. 63 - 65
- Copyright
- Copyright © Cambridge University Press 1995
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