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Na-Ca + K exchanger and Ca2+ homeostasis in retinal rod outer segments: Inactivation of the Ca2+ efflux mode and possible involvement of intracellular Ca2+ stores in Ca2+ homeostasis
Published online by Cambridge University Press: 04 February 2010
Abstract
Inactivation of the Ca2+ extrusion mode of the retinal rod Na- Ca + K exchanger is suggested to be the mechanism that prevents lowering of cytosolic free Ca2+ to < 1 nM when rod cells are saturated for a prolonged time under bright light conditions. Under these conditions, Ca2+ fluxes across disk membranes can contribute significantly to Ca2+ homeostasis in rods.
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- Copyright © Cambridge University Press 1995