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Dopamine, Parkinson's disease, and volition
Published online by Cambridge University Press: 11 August 2003
Abstract
Disruptions in dopamine transmission within the basal ganglia (BG) produce deficits in voluntary actions, that is, in the interface between cortically-generated goal representation and BG-mediated response selection. Under conditions of dopamine loss in humans and other animals, responses are impaired when they require internal generation, but are relatively intact when elicited by external stimuli.
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- © 2002 Cambridge University Press
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