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Changing maladaptive memories through reconsolidation: A role for sleep in psychotherapy?

Published online by Cambridge University Press:  08 June 2015

Susanne Diekelmann
Affiliation:
Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Tübingen 72076, [email protected]://www.medizin.uni-tuebingen.de/en/Research/Institutes/Medical+Psychology.html
Cecilia Forcato
Affiliation:
University of Buenos Aires, Institute of Physiology, Molecular Biology and Neuroscience (IFIByNE-CONICET), 1428 Capital Federal, Buenos Aires, [email protected]

Abstract

Like Lane et al., we believe that change in psychotherapy comes about by updating dysfunctional memories with new adaptive experiences. We suggest that sleep is essential to (re-)consolidate such corrective experiences. Sleep is well-known to strengthen and integrate new memories into pre-existing networks. Targeted sleep interventions might be promising tools to boost this process and thereby increase therapy effectiveness.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2015 

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References

Barnes, D. C. & Wilson, D. A. (2014) Slow-wave sleep-imposed replay modulates both strength and precision of memory. Journal of Neuroscience 34:5134–42.Google Scholar
Diekelmann, S. (2014) Sleep for cognitive enhancement. Front Systems Neuroscience 8:46.Google Scholar
Diekelmann, S., Biggel, S., Rasch, B. & Born, J. (2012) Offline consolidation of memory varies with time in slow wave sleep and can be accelerated by cuing memory reactivations. Neurobiology of Learning and Memory 98:103–11.Google Scholar
Diekelmann, S. & Born, J. (2010) The memory function of sleep. Nature Reviews Neuroscience 11:114–26.Google Scholar
Ellenbogen, J. M., Hu, P. T., Payne, J. D., Titone, D. & Walker, M. P. (2007) Human relational memory requires time and sleep. Proceedings of the National Academy of Sciences of the USA 104:7723–28.Google Scholar
Feld, G. B., Besedovsky, L., Kaida, K., Münte, T. F. & Born, J. (2014) Dopamine D2-like receptor activation wipes out preferential consolidation of high over low reward memories in human sleep. Journal of Cognitive Neuroscience 26(10): 2310–20.Google Scholar
Feld, G. B., Lange, T., Gais, S. & Born, J. (2013) Sleep-dependent declarative memory consolidation – unaffected after blocking NMDA or AMPA receptors but enhanced by NMDA coagonist D-cycloserine. Neuropsychopharmacology 38:2688–97.Google Scholar
Gais, S., Lucas, B. & Born, J. (2006) Sleep after learning aids memory recall. Learning and memory 13:259–62.Google Scholar
Gais, S., Rasch, B., Dahmen, J. C., Sara, S. & Born, J. (2011) The memory function of noradrenergic activity in non-REM sleep. Journal of Cognitive Neuroscience 23:2582–92.Google Scholar
Germain, A. (2013) Sleep disturbances as the hallmark of PTSD: Where are we now? American Journal of Psychiatry 170:372–82.Google Scholar
Goder, R., Baier, P. C., Beith, B., Baecker, C., Seeck-Hirschner, M., Junghanns, K. & Marshall, L. (2013) Effects of transcranial direct current stimulation during sleep on memory performance in patients with schizophrenia. Schizophrenia Research 144:153–54.Google Scholar
Goder, R., Boigs, M., Braun, S., Friege, L., Fritzer, G., Aldenhoff, J. B. & Hinze-Selch, D. (2004) Impairment of visuospatial memory is associated with decreased slow wave sleep in schizophrenia. Journal of Psychiatric Research 38:591–99.CrossRefGoogle ScholarPubMed
Hauner, K. K., Howard, J. D., Zelano, C. & Gottfried, J. A. (2013) Stimulus-specific enhancement of fear extinction during slow-wave sleep. Nature Neuroscience 16:1553–55.Google Scholar
Kaestner, E. J., Wixted, J. T. & Mednick, S. C. (2013) Pharmacologically increasing sleep spindles enhances recognition for negative and high-arousal memories. Journal of Cognitive Neuroscience 25:1597–610.Google Scholar
Kleim, B., Wilhelm, F. H., Temp, L., Margraf, J., Wiederhold, B. K. & Rasch, B. (2014) Sleep enhances exposure therapy. Psychological Medicine 44(7):1511–19.Google Scholar
Lahl, O., Wispel, C., Willigens, B. & Pietrowsky, R. (2008) An ultra short episode of sleep is sufficient to promote declarative memory performance. Journal of Sleep Research 17:310.Google Scholar
Landmann, N., Kuhn, M., Piosczyk, H., Feige, B., Baglioni, C., Spiegelhalder, K., Frase, L., Riemann, D., Sterr, A. & Nissen, C. (2014) The reorganisation of memory during sleep. Sleep Medicine Reviews 18(6):531–41.CrossRefGoogle ScholarPubMed
Lewis, P. A. & Durrant, S. J. (2011) Overlapping memory replay during sleep builds cognitive schemata. Trends in Cognitive Sciences 15:343–51.Google Scholar
Lu, W. & Goder, R. (2012) Does abnormal non-rapid eye movement sleep impair declarative memory consolidation?: Disturbed thalamic functions in sleep and memory processing. Sleep Medicine Review 16:389–94.Google Scholar
Marshall, L., Helgadottir, H., Molle, M. & Born, J. (2006) Boosting slow oscillations during sleep potentiates memory. Nature 444:610–13.Google Scholar
Mednick, S., Nakayama, K. & Stickgold, R. (2003) Sleep-dependent learning: A nap is as good as a night. Nature Neuroscience 6:697–98.Google Scholar
Ngo, H. V., Martinetz, T., Born, J. & Molle, M. (2013) Auditory closed-loop stimulation of the sleep slow oscillation enhances memory. Neuron 78:545–53.CrossRefGoogle ScholarPubMed
Oudiette, D. & Paller, K. A. (2013) Upgrading the sleeping brain with targeted memory reactivation. Trends in Cognitive Sciences 17:142–49.Google Scholar
Pace-Schott, E. F., Verga, P. W., Bennett, T. S. & Spencer, R. M. (2012) Sleep promotes consolidation and generalization of extinction learning in simulated exposure therapy for spider fear. Journal of Psychiatric Research 46:1036–44.Google Scholar
Payne, J. D. & Kensinger, E. A. (2010) Sleep's role in the consolidation of emotional episodic memories. Current Directions in Psychological Science 19:290–95.Google Scholar
Rasch, B. & Born, J. (2013) About sleep's role in memory. Physiological Reviews 93:681766.Google Scholar
Rasch, B., Buchel, C., Gais, S. & Born, J. (2007) Odor cues during slow-wave sleep prompt declarative memory consolidation. Science 315:1426–29.Google Scholar
Rolls, A., Makam, M., Kroeger, D., Colas, D., de Lecea, L. & Heller, H. C. (2013) Sleep to forget: Interference of fear memories during sleep. Molecular Psychiatry 18:1166–70.Google Scholar
Rudoy, J. D., Voss, J. L., Westerberg, C. E. & Paller, K. A. (2009) Strengthening individual memories by reactivating them during sleep. Science 326:1079.CrossRefGoogle ScholarPubMed
Schonauer, M., Geisler, T. & Gais, S. (2014) Strengthening procedural memories by reactivation in sleep. Journal of Cognitive Neuroscience 26:143–53.CrossRefGoogle ScholarPubMed
Spiers, H. J. & Bendor, D. (2014) Enhance, delete, incept: Manipulating hippocampus-dependent memories. Brain Research Bulletin 105:27.Google Scholar
Steiger, A., Dresler, M., Kluge, M. & Schussler, P. (2013) Pathology of sleep, hormones and depression. Pharmacopsychiatry 46(S1):S3035.Google Scholar
Stickgold, R., James, L. & Hobson, J. A. (2000) Visual discrimination learning requires sleep after training. Nature Neuroscience 3:1237–38.Google Scholar
Stickgold, R. & Walker, M. P. (2013) Sleep-dependent memory triage: Evolving generalization through selective processing. Nature Neuroscience 16:139–45.Google Scholar
Tamminen, J., Lambon Ralph, M. A. & Lewis, P. A. (2013) The role of sleep spindles and slow-wave activity in integrating new information in semantic memory. Journal of Neuroscience 33:15376–81.Google Scholar
Tononi, G. & Cirelli, C. (2014) Sleep and the price of plasticity: From synaptic and cellular homeostasis to memory consolidation and integration. Neuron 81:1234.Google Scholar
Tucker, M. A., Hirota, Y., Wamsley, E. J., Lau, H., Chaklader, A. & Fishbein, W. (2006) A daytime nap containing solely non-REM sleep enhances declarative but not procedural memory. Neurobiology of Learning and Memory 86:241–47.Google Scholar
Walker, M. P., Brakefield, T., Hobson, J. A. & Stickgold, R. (2003) Dissociable stages of human memory consolidation and reconsolidation. Nature 425:616–20.CrossRefGoogle ScholarPubMed