Hostname: page-component-586b7cd67f-gb8f7 Total loading time: 0 Render date: 2024-11-22T11:10:58.111Z Has data issue: false hasContentIssue false

But the schizophrenia connection . . .

Published online by Cambridge University Press:  01 June 1999

Jeffrey A. Gray
Affiliation:
Department of Psychology, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United [email protected]

Abstract

As well as data indicating relationships (emphasised in the target article) (1) between dopaminergic transmission in the nucleus accumbens and positive incentive motivation, and (2) between dopaminergic transmission and extraversion, other data (not accounted for by the hypotheses developed in the target article) indicate relationships (3) between accumbens dopaminergic transmission and cognitive, especially perceptual, processes that are disrupted in schizophrenia, and (4) between dopaminergic transmission and psychoticism. The tension between relationships 1 + 2 and 3 + 4 is discussed and a tentative resolution proposed.

Type
Open Peer Commentary
Copyright
© 1999 Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)