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Therapeutic affect reduction, emotion regulation, and emotional memory reconsolidation: A neuroscientific quandary

Published online by Cambridge University Press:  08 June 2015

Kevin S. LaBar*
Affiliation:
Duke University, Center for Cognitive Neuroscience, Duke University, Durham, NC 27708-0999. [email protected]://www.labaratory.org

Abstract

Lane et al. emphasize the role of emotional arousal as a precipitating factor for successful psychotherapy. However, as therapy ensues, the arousal diminishes. How can the unfolding therapeutic process generate long-term memories for reconsolidated emotional material without the benefit of arousal? Studies investigating memory for emotionally regulated material provide some clues regarding the neural pathways that may underlie therapy-based memory reconsolidation.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2015 

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References

Agren, T., Engman, J., Frick, A., Björkstrand, J., Larsson, E.-M., Furmark, T. & Fredrikson, M. (2012) Disruption of reconsolidation erases a fear memory trace in the human amygdala. Science 337(6101):1550–52.Google Scholar
Besnard, A., Caboche, J. & Laroche, S. (2012) Reconsolidation of memory: A decade of debate. Progress in Neurobiology 99(1):6180. Available at: http://doi.org/10.1016/j.pneurobio.2012.07.002.Google Scholar
Diergaarde, L., Anton, N. M. & DeVries, T. J. (2008) Pharmacological manipulation of memory reconsolidation: Towards a novel treatment of pathogenic memories. European Journal of Pharmacology 585:453–57.CrossRefGoogle ScholarPubMed
Dillon, D. G., Ritchey, M., Johnson, B. D. & LaBar, K. S. (2007) Dissociable effects of conscious emotion regulation strategies on explicit and implicit memory. Emotion 7(2):354–65.CrossRefGoogle ScholarPubMed
Dolcos, F., LaBar, K. S. & Cabeza, R. (2004) Dissociable effects of arousal and valence on prefrontal activity indexing emotional evaluation and subsequent memory: An event-related fMRI study. NeuroImage 23:6474.CrossRefGoogle ScholarPubMed
Hayes, J. P., Morey, R. A., Petty, C. M., Seth, S., Smoski, M. J., McCarthy, G. & LaBar, K. S. (2010) Staying cool when things get hot: Emotion regulation modulates neural mechanisms of memory encoding. Frontiers in Human Neuroscience 4:230.Google Scholar
Kross, E., Davidson, M., Weber, J. & Ochsner, K. N. (2009) Coping with emotions past: The neural bases of regulating affect associated with negative autobiographical memories. Biological Psychiatry 65(5):361–66.CrossRefGoogle ScholarPubMed
Lieberman, M. D., Eisenberger, N. I., Crockett, M. J., Tom, S. M., Pfeifer, J. H. & Way, B. M. (2007) Putting feelings into words: Affect labeling disrupts amygdala activity in response to affective stimuli. Psychological Science 18(5):421–28.Google Scholar
McGaugh, J. L. (2000) Memory: A century of consolidation. Science 287:248–51.CrossRefGoogle ScholarPubMed
Nader, K. & Hardt, O. (2009) A single standard for memory: The case for reconsolidation. Nature Reviews Neuroscience 10(3):224234. Available at: http://doi.org/10.1038/nrn2590.Google Scholar
Ochsner, K. N., Silvers, J. A. & Buhle, J. T. (2012) Functional imaging studies of emotion regulation: A synthetic review and evolving model of the cognitive control of emotion. Annals of the New York Academy of Sciences 1251:E124.CrossRefGoogle ScholarPubMed
Phelps, E. A., LaBar, K. S. & Spencer, D. D. (1997) Memory for emotional words following unilateral temporal lobectomy. Brain and Cognition 35(1):85109.CrossRefGoogle ScholarPubMed
Schiller, D., Kanen, J. W., LeDoux, J. E., Monfils, M.-H. & Phelps, E. A. (2013) Extinction during reconsolidation of threat memory diminishes prefrontal cortex involvement. Proceedings of the National Academy of Sciences USA 110(50):20040–45.CrossRefGoogle ScholarPubMed
Schiller, D. & Phelps, E. A. (2011) Does reconsolidation occur in humans? Frontiers in Behavioral Neuroscience 5:24.CrossRefGoogle ScholarPubMed
Winecoff, A., LaBar, K. S., Madden, D., Cabeza, R. & Huettel, S. A. (2011) Cognitive and neural contributors to emotion regulation in aging. Social Cognitive and Affective Neuroscience 6:165–76.Google Scholar