Hostname: page-component-78c5997874-j824f Total loading time: 0 Render date: 2024-11-03T05:10:17.382Z Has data issue: false hasContentIssue false

Reconsolidation or re-association?

Published online by Cambridge University Press:  08 June 2015

Sue Llewellyn*
Affiliation:
Faculty of Humanities, University of Manchester, Manchester M15 6PB, United Kingdom. [email protected]://www.humanities.manchester.ac.uk

Abstract

The target article argues memory reconsolidation demonstrates how therapeutic change occurs, grounding psychotherapy in brain science. However, consolidation has become an ambiguous term, a disadvantage applying also to its derivative – reconsolidation. The concept of re-association (involving active association between memories during rapid eye movement [REM] dreams followed by indexation and network junction instantiation during non-rapid eye movement [NREM] periods) brings greater specificity and explanatory power to the possible brain correlates of therapeutic change.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2015 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bliss, T. V. & Collingridge, G. L. (1993) A synaptic model of memory: Long-term potentiation in the hippocampus. Nature 361(6407):3139.Google Scholar
Buzsáki, G. (2005) Theta rhythm of navigation: Link between path integration and landmark navigation, episodic and semantic memory. Hippocampus 15:827–40.CrossRefGoogle ScholarPubMed
Chklovskii, D. B., Mel, B. W. & Svoboda, K. (2004) Cortical rewiring and information storage. Nature 431(7010):782–88.Google Scholar
Dudai, Y. (2004) The neurobiology of consolidation, or, how stable is the engram? Annual Review of Psychology 55:5186.Google Scholar
Ellenbogen, J. M., Hu, P. T., Payne, J. D., Titone, D. & Walker, M. P. (2007) Human relational memory requires time and sleep. Proceedings of the National Academy of Sciences of the USA 104:7723–28.Google Scholar
Esser, S. K., Hill, S. & Tononi, G. (2009) Breakdown of effective connectivity during slow wave sleep: Investigating the mechanism underlying a cortical gate using large-scale modeling. Journal of Neurophysiology 102(4):2096–111.Google Scholar
Fosse, M. J., Fosse, R., Hobson, J. A. & Stickgold, R. J. (2003) Dreaming and episodic memory: A functional dissociation. Journal of Cognitive Neuroscience 15:19.Google Scholar
Frankland, P. W. & Bontempi, B. (2005) The organization of recent and remote memories. Nature Reviews: Neuroscience 6:119–30.Google Scholar
Freud, S. (1899/1999) The interpretation of dreams, trans. Crick, J.. Oxford University Press. (Original work published in 1899.)Google Scholar
Fuster, J. M. (1997) Network memory. Trends in Neurosciences 20(10):451–59.Google Scholar
Fuster, J. M. (1999) Memory in the cerebral cortex: An empirical approach to neural networks in the human and nonhuman primate. MIT Press.Google Scholar
Fuster, J. M. (2006) The cognit: A network model of cortical representation. International Journal of Psychophysiology 60(2):125–32.Google Scholar
Fuster, J. M. (2009) Cortex and memory: Emergence of a new paradigm. Journal of Cognitive Neuroscience 21(11):2047–72.Google Scholar
Gazzaniga, M. (1998) The mind's past. University of California Press.Google Scholar
Hartmann, E. (1996) Outline for a theory on the nature and functions of dreaming. Dreaming 6(2):147–70.Google Scholar
Hebb, D. O. (1949) The organization of behavior: A neuropsychological theory. Wiley.Google Scholar
Hirsh, R. (1974) The hippocampus and contextual retrieval of information from memory: A theory. Behavioral Biology 12(4):421–44.Google Scholar
Hobson, J. A. (1988) The dreaming brain: How the brain creates both the sense and the nonsense of dreams. Basic.Google Scholar
Llewellyn, S. (2013a) Such stuff as dreams are made on? Elaborative encoding, the ancient art of memory and the hippocampus. [Target Article] Behavioral and Brain Sciences 36(6):589607.Google Scholar
Llewellyn, S. (2013b) Such stuff as REM and NREM dreams are made on? An elaboration. [Response article] Behavioral and Brain Sciences 36(6):634–46.Google Scholar
Massimini, M., Ferrarelli, F., Huber, R., Esser, S. K., Singh, H. & Tononi, G. (2005) Breakdown of cortical effective connectivity during sleep. Science 309:2228–32.Google Scholar
Müller, G. E. & Pilzecker, A. (1900) Experimentelle Beiträge zur Lehre vom Gedächtnis. Zeitschrift für Psychologie: Ergänzungsband 1:1300.Google Scholar
Nielsen, T. A. & Stenstrom, P. (2005) What are the memory sources of dreaming? Nature 437(7063):1286–89.Google Scholar
Spoormaker, V. I., Schröter, M. S., Gleiser, P. M., Andrade, K. C., Dresler, M., Wehrle, R., Sämann, P. G. & Czisch, M. (2010) Development of a large-scale functional brain network during human non-rapid eye movement sleep. Journal of Neuroscience 30(34):11379–87.Google Scholar
Sporns, O., Chialvo, D. R., Kaiser, M. & Hilgetag, C. C. (2004) Organization, development and function of complex brain networks. Trends in Cognitive Sciences 8(9):418–25.Google Scholar
Stickgold, R. & Walker, M. P. (2005) Memory consolidation and reconsolidation: What is the role of sleep? Trends in Neurosciences 28(8):408–15.CrossRefGoogle ScholarPubMed
Tamminen, J., Payne, J. D., Stickgold, R., Wamsley, E. J. & Gaskell, M. G. (2010) Sleep spindle activity is associated with the integration of new memories and existing knowledge. The Journal of Neuroscience 30(43):14356–60.Google Scholar
Teyler, T. J. & DiScenna, P. (1986) The hippocampal memory indexing theory. Behavioral Neuroscience 100(2):147–54.CrossRefGoogle ScholarPubMed
Teyler, T. J. & Rudy, J. W. (2007) The hippocampal indexing theory and episodic memory: Updating the index. Hippocampus 17(12):1158–69.Google Scholar
Tononi, G., Sporns, O. & Edelman, G. M. (1994) A measure for brain complexity: Relating functional segregation and integration in the nervous system. Proceedings of the National Academy of Sciences USA 91:5033–37.Google Scholar
Tulving, E. & Thomson, D. M. (1973) Encoding specificity and retrieval processes in episodic memory. Psychological Review 80(5):352–73.CrossRefGoogle Scholar
Wagner, U., Gais, S., Haider, H., Verleger, R. & Born, J. (2004) Sleep inspires insight. Nature 427(6972):352–55.Google Scholar
Walker, M. P. & Stickgold, R. (2010) Overnight alchemy: Sleep-dependent memory evolution. Nature Reviews: Neuroscience 11(3):218.Google Scholar
Zeki, S. (1978) Functional specialization in the visual cortex of the rhesus monkey. Nature 274:423–28.Google Scholar
Zeki, S. & Shipp, S. (1988) The functional logic of cortical connections. Nature 335:311–17.Google Scholar