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Psychosis and autism as two developmental windows on a disordered social brain

Published online by Cambridge University Press:  26 June 2008

Sophie van Rijn
Affiliation:
Department of Clinical Child and Adolescent Studies, Centre for the Study of Developmental Disorders, Leiden University, 2333 AK Leiden, The Netherlands
Hanna Swaab
Affiliation:
Department of Clinical Child and Adolescent Studies, Centre for the Study of Developmental Disorders, Leiden University, 2333 AK Leiden, The Netherlands
André Aleman
Affiliation:
BCN Neuroimaging Center, University of Gröningen, 9713 AW Gröningen, The [email protected] [email protected] [email protected]

Abstract

With regard to social-cognitive deficits in autism and psychosis, Crespi & Badcock's (C&B's) theory does not incorporate the developmental context of the disorders. We propose that there is significant overlap in social-cognitive impairments, but that the exact manifestation of social-cognitive deficits is highly dependent on the dynamics of cognitive development and hence different in autism as compared to psychosis.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2008

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References

Bentall, R. P. & Kinderman, P. (1998) Psychological processes and delusional beliefs: Implications for the treatment of paranoid states. In: Outcome and innovation in psychological treatment of schizophrenia, ed. Lewis, S., Tarrier, N. & Wykcs, T., pp. 119–44. Wiley.Google Scholar
Blackshaw, A. J., Kinderman, P., Hare, D. J. & Hatton, C. (2001) Theory of mind, causal attribution and paranoia in Asperger syndrome. Autism 5(2):147–63.CrossRefGoogle ScholarPubMed
Bleuler, E. (1911) Dementia Praecox oder Gruppe der Schizophrenien [Dementia praecox or group of schizophrenias]. Deutike. Also in: Handbuch der Psychiatrie, ed. Bleuler, E. & Dover, P.. Aschaffenburg. (1951 English edition, Textbook of Psychiatry, trans. Bleuler, E. & Dover, P..Google Scholar
Craig, J. S., Hatton, C., Craig, F. B. & Bentall, R. P. (2004) Persecutory beliefs, attributions and theory of mind: Comparison of patients with paranoid delusions, Asperger's syndrome and healthy controls. Schizophrenia Research 69:2933.CrossRefGoogle ScholarPubMed
Harrington, L., Langdon, R., Siegert, R. J. & McClure, J. (2005a) Schizophrenia, theory of mind, and persecutory delusions. Cognitive Neuropsychiatry 10:87104.CrossRefGoogle ScholarPubMed
Karmiloff-Smith, A. (1997) Crucial differences between developmental cognitive neuroscience and adult neuropsychology. Developmental Neuropsychology 13(4):513–24.CrossRefGoogle Scholar
Mouridsen, S. E., Rich, B. & Isager, T. (2008) Psychiatric disorders in adults diagnosed as children with atypical autism. A case control study. Journal of Neural Transmission 115(1):135–38.CrossRefGoogle ScholarPubMed
Pickup, G. J. (2006) Theory of mind and its relation to schizotypy. Cognitive Neuropsychiatry 11(2):177–92.CrossRefGoogle ScholarPubMed
Pinkham, A. E., Hopfinger, J. B., Pelphrey, K. A., Piven, J. & Penn, D. L. (2008) Neural bases for impaired social cognition in schizophrenia and autism spectrum disorders. Schizophrenia Research 99 (1–3):164–75.CrossRefGoogle ScholarPubMed
Rourke, B. P., Bakker, D. J., Fisk, J. L. & Strang, J. D. (1983) Child neuropsychology. Guilford Press.Google Scholar
Sprong, M., Schothorst, P., Vos, E., Hox, J. & van Engeland, H. (2007) Theory of mind in schizophrenia: Meta-analysis. British Journal of Psychiatry 191:513.CrossRefGoogle ScholarPubMed
van Rijn, S., Aleman, A., Swaab, H. & Kahn, R. S. (2006a) Klinefelter's syndrome (karyotype 47,XXY) and schizophrenia-spectrum pathology. British Journal of Psychiatry 189(5):459–61.CrossRefGoogle ScholarPubMed
van Rijn, S., Aleman, A., Swaab, H., Krijn, T., Vingerhoets, G. & Kahn, R. (2007) What is said versus how it is said: Comprehension of affective prosody in men with Klinefelter (47,XXY) syndrome. Journal of the International Neuropsychological Society 13(6):1065–70.CrossRefGoogle ScholarPubMed
van Rijn, S., Aleman, A., Swaab, H., Krijn, T., Vingerhoets, G. & Kahn, R. (in press) Social behavior and autism traits in a sex chromosomal disorder: Klinefelter (47, XXY) syndrome. Journal of Autism and Developmental Disorders.Google Scholar
van Rijn, S., Swaab, H., Aleman, A. & Kahn, R. S. (2006b) X chromosomal effects on social cognitive processing and emotion regulation: A study with Klinefelter men (47, XXY). Schizophrenia Research 84 (2–3):194203.CrossRefGoogle Scholar