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Long term potentiation and CaM-sensitive adenylyl cyclase: Long-term prospects

Published online by Cambridge University Press:  04 February 2010

Warren Heideman
Warren Heideman*
Affiliation:
Division of Pharmacology, School of Pharmacy, University of Wisconsin, Madison, WI 53706. [email protected]
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Abstract

The type I CaM-sensitive adenylyl cyclase is in a position to integrate signals from multiple inputs, consistent with the requirements for mediating long term potentiation (LTP). Biochemical and genetic evidence supports the idea that this enzyme plays an important role inc LTP. However, more work is needed before we will be certain of the role that CaM-sensitive adenylyl cyclases play in LTP.

Type
Article Commentary
Information
Behavioral and Brain Sciences , Volume 18 , Special Issue 3: An International Journal of Current Research and Theory with Open Peer Commentary , September 1995 , pp. 477 - 478
Copyright
Copyright © Cambridge University Press 1995

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