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Does progressive aphantasia exist? The hypothetical role of aphantasia in the diagnosis of neurodegenerative diseases

Published online by Cambridge University Press:  18 November 2022

Emilia J. Sitek Open the ORCID record for Emilia J. Sitek [Opens in a new window]  and
Seweryna Konieczna Open the ORCID record for Seweryna Konieczna [Opens in a new window]
Emilia J. Sitek
Affiliation:
Division of Neurological and Psychiatric Nursing, Faculty of Health Sciences, Medical University of Gdansk, 80-210 Gdansk, [email protected] Department of Neurology, St. Adalbert Hospital, Copernicus Ltd., 80-462Gdansk, Poland
Seweryna Konieczna
Affiliation:
Department of History and Philosophy of Medical Sciences, Faculty of Health Sciences, Medical University of Gdansk, 80-210Gdansk, [email protected] Department of Developmental Neurology, University Medical Center, Medical University of Gdańsk, 80-210 Gdańsk, Poland
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Abstract

Aphantasia is a heterogeneous neuropsychological syndrome consisting of the inability to create mental images. We argue that its progressive form may be a harbinger of dementia. Aphantasia may manifest as the inability to create any mental images or to create complex scenes, inability to spontaneously initiate generation of mental images, and/or inability to visualize a sequence of events.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 45 , 2022 , e299
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Copyright
Copyright © The Author(s), 2022. Published by Cambridge University Press

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References

Boot, N., Baas, M., van Gaal, S., Cools, R., & De Dreu, C. (2017). Creative cognition and dopaminergic modulation of fronto-striatal networks: Integrative review and research agenda. Neuroscience and Biobehavioral Reviews, 78, 13–23. doi: doi.org/10.1016/j.neubiorev.2017.04.007CrossRefGoogle ScholarPubMed
Brosch, R. (2018). What we “see” when we read: Visualization and vividness in reading fictional narratives. Cortex, 105, 135–143. doi: doi.org/10.1016/j.cortex.2017.08.020CrossRefGoogle ScholarPubMed
Cerasa, A. (2018). Re-examining the Parkinsonian personality hypothesis: A systematic review. Personality and Individual Differences, 130, 41–50.CrossRefGoogle Scholar
Clément, F., Belleville, S., & Gauthier, S. (2008). Cognitive complaint in mild cognitive impairment and Alzheimer's disease. Journal of the International Neuropsychological Society: JINS, 14(2), 222–232. doi: doi.org/10.1017/S1355617708080260CrossRefGoogle ScholarPubMed
Evans, J. J., Heggs, A. J., Antoun, N., & Hodges, J. R. (1995). Progressive prosopagnosia associated with selective right temporal lobe atrophy. A new syndrome? Brain, 118(Pt 1), 1–13. doi: doi.org/10.1093/brain/118.1.1CrossRefGoogle ScholarPubMed
Floud, S., Balkwill, A., Sweetland, S., Brown, A., Reus, E. M., Hofman, A., … Beral, V. (2021). Cognitive and social activities and long-term dementia risk: The prospective UK Million Women Study. The Lancet Public Health, 6(2), e116–e123. doi: doi.org/10.1016/S2468-2667(20)30284-XCrossRefGoogle ScholarPubMed
Galton, F. (1880). Statistics of mental imagery. Mind, 19, 301–318. doi: doi.org/10.1093/mind/os-V.19.301CrossRefGoogle Scholar
Garcia-Ruiz, P. J., Martinez Castrillo, J. C., & Desojo, L. V. (2019). Creativity related to dopaminergic treatment: A multicenter study. Parkinsonism & Related Disorders, 63, 169–173. doi: doi.org/10.1016/j.parkreldis.2019.02.010CrossRefGoogle ScholarPubMed
Goodale, M. A., & Milner, A. D. (1992). Separate visual pathways for perception and action. Trends in Neurosciences, 15(1), 20–25. doi: doi.org/10.1016/0166-2236(92)90344-8CrossRefGoogle ScholarPubMed
Goodale, M. A., & Westwood, D. A. (2004). An evolving view of duplex vision: Separate but interacting cortical pathways for perception and action. Current Opinion in Neurobiology, 14(2), 203–211. doi: doi.org/10.1016/j.conb.2004.03.002CrossRefGoogle ScholarPubMed
Mason, S. L., Schaepers, M., & Barker, R. A. (2021). Problems with social cognition and decision-making in Huntington's disease: Why is it important? Brain Sciences, 11(7), 838. doi: doi.org/10.3390/brainsci11070838CrossRefGoogle ScholarPubMed
Mendez, M. F., Moheb, N., Desarzant, R. E., & Teng, E. H. (2018). The progressive acalculia presentation of parietal variant Alzheimer's disease. Journal of Alzheimer's Disease: JAD, 63(3), 941–948. doi: doi.org/10.3233/JAD-180024CrossRefGoogle ScholarPubMed
Milton, F., Fulford, J., Dance, C., Gaddum, J., Heuerman-Williamson, B., Jones, K., … Zeman, A. (2021). Behavioral and neural signatures of visual imagery vividness extremes: Aphantasia versus hyperphantasia. Cerebral Cortex Communications, 2(2), tgab035. doi: doi.org/10.1093/texcom/tgab035CrossRefGoogle ScholarPubMed
Nanay, B. (2016). The role of imagination in decision-making. Mind & Language, 31, 127–143. doi: doi.org/10.1111/mila.12097CrossRefGoogle Scholar
Ramanan, S., Alaeddin, S., Goldberg, Z. L., Strikwerda-Brown, C., Hodges, J. R., & Irish, M. (2018). Exploring the contribution of visual imagery to scene construction – evidence from posterior cortical atrophy. Cortex, 106, 261–274. doi: doi.org/10.1016/j.cortex.2018.06.016CrossRefGoogle ScholarPubMed
Robinson, G. A. (2013). Primary progressive dynamic aphasia and parkinsonism: Generation, selection and sequencing deficits. Neuropsychologia, 51(13), 2534–2547. doi: doi.org/10.1016/j.neuropsychologia.2013.09.038CrossRefGoogle ScholarPubMed
Robinson, G. A., Spooner, D., & Harrison, W. J. (2015). Frontal dynamic aphasia in progressive supranuclear palsy: Distinguishing between generation and fluent sequencing of novel thoughts. Neuropsychologia, 77, 62–75. doi: doi.org/10.1016/j.neuropsychologia.2015.08.001CrossRefGoogle ScholarPubMed
Rodriguez, C., Albanese, E., Pegna, A., Toma, S., Ackermann, M., Tombeur, E., … Giannakopoulos, P. (2016). Personality-related determinants of subtle cognitive decline in old age: A population-based study. Dementia and Geriatric Cognitive Disorders Extra, 6(1), 120–1322016. doi: doi.org/10.1159/000441388CrossRefGoogle Scholar
Santangelo, G., Garramone, F., Baiano, C., D'Iorio, A., Piscopo, F., Raimo, S., & Vitale, C. (2018). Personality and Parkinson's disease: A meta-analysis. Parkinsonism & Related Disorders, 49, 67–74.CrossRefGoogle ScholarPubMed
Wilson, N. A., Ramanan, S., Roquet, D., Goldberg, Z. L., Hodges, J. R., Piguet, O., & Irish, M. (2020). Scene construction impairments in frontotemporal dementia: Evidence for a primary hippocampal contribution. Neuropsychologia, 137, 107327. doi: doi.org/10.1016/j.neuropsychologia.2019.107327CrossRefGoogle ScholarPubMed
Young, A. W., & Wal, A. W. (1996). Charcot's case of impaired imagery. In Code, Chris, Wallesch, Claus-W., Joannette, Yves & Roch Lecours, Andre (Eds.), Classic cases in neuropsychology (Vol. I, pp. 31–44). Psychology Press.Google Scholar
Zago, S., Allegri, N., Cristoffanini, M., Ferrucci, R., Porta, M., & Priori, A. (2011). Is the Charcot and Bernard case (1883) of loss of visual imagery really based on neurological impairment? Cognitive Neuropsychiatry, 16(6), 481–504. doi: doi.org/10.1080/13546805.2011.556024CrossRefGoogle ScholarPubMed
Zeman, A. Z., Della Sala, S., Torrens, L. A., Gountouna, V. E., McGonigle, D. J., & Logie, R. H. (2010). Loss of imagery phenomenology with intact visuo-spatial task performance: A case of “blind imagination”. Neuropsychologia, 48, 145–155. doi: 10.1016/j.neuropsychologia.2009.08.024CrossRefGoogle Scholar
Zeman, A., Dewar, M., & Della Sala, S. (2015). Lives without imagery – congenital aphantasia. Cortex, 73, 378–380. doi: doi.org/10.1016/j.cortex.2015.05.019CrossRefGoogle ScholarPubMed
Zeman, A., Milton, F., Della Sala, S., Dewar, M., Frayling, T., Gaddum, J., … Winlove, C. (2020). Phantasia – The psychological significance of lifelong visual imagery vividness extremes. Cortex, 130, 426–440. doi: doi.org/10.1016/j.cortex.2020.04.003CrossRefGoogle ScholarPubMed