Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-05T15:43:31.298Z Has data issue: false hasContentIssue false

Creativity, psychosis, autism, and the social brain

Published online by Cambridge University Press:  26 June 2008

Michael Fitzgerald
Affiliation:
Department of Psychiatry, Trinity College, Dublin 2, Ireland. [email protected]://www.medicine.tcd.ie/psychiatry/[email protected]://www.medicine.tcd.ie/psychiatry/research/neuropsychiatry/
Ziarih Hawi
Affiliation:
Department of Psychiatry, Trinity College, Dublin 2, Ireland. [email protected]://www.medicine.tcd.ie/psychiatry/[email protected]://www.medicine.tcd.ie/psychiatry/research/neuropsychiatry/

Abstract

In the target article, Crespi & Badcock (C&B) propose a novel hypothesis based on observations that a large set of phenotypic traits exhibit diametrically opposite phenotypes in autism-spectrum versus psychotic-spectrum conditions. They propose that development of these conditions is mediated in part by alterations in “genomic imprinting.” This hypothesis is based on the model of the Prader-Willi and Angelman syndromes. The authors have produced a masterful discussion of the differences between psychosis and autism. Of course, another article could be written on the similarities.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

McAlonan, G. M., Daly, E., Kumari, V., Critchley, H. D., van Amelsvoort, T., Suckling, J., Simmons, A., Sigmundsson, T., Greenwood, K., Russell, A., Schmitz, N., Happé, F., Howlin, P. & Murphy, D. G. M. (2002) Brain anatomy and sensorimotor gating in Asperger's syndrome. Brain 125:1594–606.CrossRefGoogle ScholarPubMed