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Use of siblings as controls in case-control association studies

Published online by Cambridge University Press:  01 January 1998

Abstract

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Ann. Hum. Genet. (1997), 61, 319–333

Correction and additional citation

The author has noticed two errors he failed to correct in this paper, as follows:

(i) Page 329: ‘Thus if the case has genotype AA and the control is BC one adds 0.5 to TAB and 0.5 to TACshould read ‘Thus if the case has genotype AD and the control is BC one adds 0.5 to each of TAB, TAC, TDB and TDC.’

(ii) Table 3, first ‘Score’ line: ‘0.25tAB, 0.5tAC, 0.5tCBshould read ‘0.5tAB, 0.5tAC, 0.5tCB.’

Since the paper was published the author has learned that the use of siblings as controls was proposed by L. S. Penrose, and a method of analysis devised by C. A. B. Smith, for application to studies of blood groups and duodenal ulcer (Clarke et al. 1956). The author is grateful to C. A. Clarke for making him aware of this previous work.

Clarke, C. A., Wyn Edwards, J., Haddock, D. R. W., Howel-Evans, A. W., McConnell, R. B. & Sheppard, P. M. ABO blood groups and secretor character in duodenal ulcer. Br. Med. J. (1956), 725–731.

Type
Corrigendum
Copyright
© University College London 1998