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The human dendritic cell marker CD83 maps to chromosome 6p23

Published online by Cambridge University Press:  01 March 1999

S. BERCHTOLD ,
T. JONES ,
P. MÜHL-ZÜRBES ,
D. SHEER ,
G. SCHULER  and
A. STEINKASSERER
S. BERCHTOLD
Affiliation:
Department of Dermatology, University of Erlangen-Nürnberg, Hartmannstraße 14, D-91052 Erlangen, Germany
T. JONES
Affiliation:
Imperial Cancer Research Fund, Lincoln's Inn Field, London WC2A 3PX, U.K.
P. MÜHL-ZÜRBES
Affiliation:
Department of Dermatology, University of Erlangen-Nürnberg, Hartmannstraße 14, D-91052 Erlangen, Germany
D. SHEER
Affiliation:
Imperial Cancer Research Fund, Lincoln's Inn Field, London WC2A 3PX, U.K.
G. SCHULER
Affiliation:
Department of Dermatology, University of Erlangen-Nürnberg, Hartmannstraße 14, D-91052 Erlangen, Germany
A. STEINKASSERER
Affiliation:
Department of Dermatology, University of Erlangen-Nürnberg, Hartmannstraße 14, D-91052 Erlangen, Germany
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Abstract

The chromosomal localization of the human CD83 gene was determined using somatic cell hybrids, a radiation hybrid mapping panel and FISH analysis on human metaphase chromosomes. PCR-based analysis of a single chromosome hybrid panel identified the presence of the CD83 gene on human chromosome 6 and subsequent analysis of the Genebridge4 radiation panel located the gene between AFMa192wg9 and AFMb322wd1 with a lod score of 9.2. Finally, using FISH analysis the CD83 gene was localized to chromosome 6 band p23.

Type
SHORT COMMUNICATION
Information
Annals of Human Genetics , Volume 63 , Issue 2 , March 1999 , pp. 181 - 183
Copyright
© University College London 1999

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