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Linkage mapping of quantitative trait loci in humans: an overview

Published online by Cambridge University Press:  13 December 2002

S. GHOSH ,
T. REICH  and
P. P. MAJUMDER
S. GHOSH
Affiliation:
Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
T. REICH
Affiliation:
Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA
P. P. MAJUMDER
Affiliation:
Anthropology and Human Genetics Unit, Indian Statistical Institute, Kolkata, India
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Abstract

In this article, we provide an overview of the different statistical procedures that have been developed for linkage mapping of quantitative trait loci. We outline the model assumptions, the data requirements and the underlying tests for linkage for the different methods.

Type
Research Article
Information
Annals of Human Genetics , Volume 66 , Issue 5-6 , November 2002 , pp. 431 - 438
Copyright
© University College London 2002

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