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Percentile growth charts for biomedical studies using a porcine model

Published online by Cambridge University Press:  01 December 2008

A. M. Corson ,
J. Laws ,
A. Laws ,
J. C. Litten ,
I. J. Lean  and
L. Clarke
A. M. Corson
Affiliation:
Faculty of Natural Sciences, Imperial College London, Wye Campus, Wye, Kent TN25 5AH, UK
J. Laws
Affiliation:
Faculty of Natural Sciences, Imperial College London, Wye Campus, Wye, Kent TN25 5AH, UK
A. Laws
Affiliation:
Faculty of Natural Sciences, Imperial College London, Wye Campus, Wye, Kent TN25 5AH, UK
J. C. Litten
Affiliation:
Department of Agriculture, Policies and Development, The University of Reading, Earley Gate, P.O. Box 237, Reading, UK
I. J. Lean
Affiliation:
Faculty of Natural Sciences, Imperial College London, Wye Campus, Wye, Kent TN25 5AH, UK
L. Clarke*
Affiliation:
Faculty of Natural Sciences, Imperial College London, Wye Campus, Wye, Kent TN25 5AH, UK
*
E-mail: [email protected]
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Abstract

Increasing rates of obesity and heart disease are compromising quality of life for a growing number of people. There is much research linking adult disease with the growth and development both in utero and during the first year of life. The pig is an ideal model for studying the origins of developmental programming. The objective of this paper was to construct percentile growth curves for the pig for use in biomedical studies. The body weight (BW) of pigs was recorded from birth to 150 days of age and their crown-to-rump length was measured over the neonatal period to enable the ponderal index (PI; kg/m3) to be calculated. Data were normalised and percentile curves were constructed using Cole’s lambda-mu-sigma (LMS) method for BW and PI. The construction of these percentile charts for use in biomedical research will allow a more detailed and precise tracking of growth and development of individual pigs under experimental conditions.

Keywords

percentile growth chartsponderal indexporcine biomedical modeldevelopmental programmingadult disease
Type
Full Paper
Information
animal , Volume 2 , Issue 12 , December 2008 , pp. 1795 - 1801
Copyright
Copyright © The Animal Consortium 2008

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References

Allen, AD, Lasley, JF 1960. Milk production of sows. Journal of Animal Science 19, 150–155.CrossRefGoogle Scholar
Barker, DJP 1995a. The fetal origin of adult disease: the Wellcome Foundation Lecture 1994. Proceedings of the Royal Society, B. Biological Science 262, 37–43.Google ScholarPubMed
Barker, DJP 1995b. Fetal origins of coronary heart disease. British Medical Journal 311, 171–174.CrossRefGoogle ScholarPubMed
Barker, DJP 1998. In utero programming of chronic disease. Clinical Science 95, 115–128.CrossRefGoogle ScholarPubMed
Barker, DJP 2004. The developmental origins of well-being. Philosophical Transactions The Royal Society, B. Biological Sciences 359, 1359–1366.CrossRefGoogle ScholarPubMed
Barker, DJP, Osmond, C, Winter, PD, Margetts, BM, Simmonds, SJ 1989. Weight in infancy and death from ischaemic heart disease. Lancet 334, 577–580.CrossRefGoogle Scholar
Bazer, FW, Ford, JJ, Kensinger, RS 2001. Reproductive physiology. In Biology of the domestic pig (ed. WG Pond and HJ Mersmann), pp. 150–224. Cornwell University Press, Ithaca, NY, USA.Google Scholar
Bhargava, SK, Sachdev, HPS, Fall, CHD, Osmond, C, Lakshmy, R, Barker, DJP, Biswas, SKD, Ramji, S, Prabhakaran, D, Reddy, KS 2004. Relation of serial changes in childhood body-mass index to impaired glucose tolerance in young adulthood. New England Journal of Medicine 350, 865–875.CrossRefGoogle ScholarPubMed
Cede, P, Bilkei, G 2004. The effect of modified eros centre, outdoor raising or conventional group housing on breeding gilts and its effects on reproductive performance over four parities. Theriogenology 61, 185–194.CrossRefGoogle ScholarPubMed
Cole, TJ 1995. Conditional reference charts to assess weight gain in British infants. Archives of Diseases in Childhood 73, 8–16.CrossRefGoogle ScholarPubMed
Cole, TJ, Green, PJ 1992. Smoothing reference centile curves: the LMS method and penalized likelihood. Statistics in Medicine 11, 1305–1319.CrossRefGoogle ScholarPubMed
Cooper, JE 1975. The use of the pig as an animal model to study problems associated with low birthweight. Laboratory Animals 9, 329–336.CrossRefGoogle ScholarPubMed
DEFRA 2003. Code of recommendations for the welfare of livestock. Retrieved February 14, 2005, from http://www.defra.gov.ul/animalh/welfare/farmed/pigs/pigcode.pdfGoogle Scholar
Dowdney, L, Skuse, D, Heptinstall, E, Puckering, C, Zur-Szpiro, S 1987. Growth retardation and developmental delay amongst inner-city children. Journal of Child Psychology and Psychiatry and Allied Disciplines 28, 529–541.CrossRefGoogle ScholarPubMed
Eriksson, JG, Forsen, T, Tuomilehto, J, Osmond, C, Barker, DJP 2001. Early growth and coronary heart disease in later life: longitudinal study. British Medical Journal 322, 949–953.CrossRefGoogle ScholarPubMed
Fenton, TR, Sauve, RS 2007. Using the LMS method to calculate z-scores for the Fenton preterm infant growth chart. European Journal of Clinical Nutrition 61, 1380–1385.CrossRefGoogle ScholarPubMed
Flegal, KM 1999. Curve smoothing and transformations in the development of growth curves. American Journal of Clinical Nutrition 70 (suppl.), 163S–165S.CrossRefGoogle ScholarPubMed
Forsen, T, Eriksson, JG, Tuomilehto, J, Teramo, K, Osmond, C, Barker, DJP 1997. Mother’s weight in pregnancy and coronary heart disease in a cohort of Finnish men: follow-up study. British Medical Journal 315, 837–840.CrossRefGoogle Scholar
Freeman, JV, Cole, TJ, Chinn, S, Jones, PRM, White, EM, Preece, MA 1995. Cross-sectional stature and weight reference curves for the UK 1990. Archives of Diseases in Childhood 73, 17–24.CrossRefGoogle ScholarPubMed
Healy, MJR 1992. Normalizing transformations for growth standards. Annals of Human Biology 19, 521–526.CrossRefGoogle ScholarPubMed
Koletzko B 2006. Long-term consequences of early feeding on later obesity risk. In Protein and energy requirements in infancy and childhood (ed. J Rigo and EE Ziegler), Nestlé Nutrition Workshop Ser Pediatr Program, vol. 58, pp. 1–18.CrossRefGoogle Scholar
Lunstra, DD, Ford, JJ, Christenson, RK, Allrich, RD 1986. Changes in Leydig cell ultrastructure and function during pubertal development in the boar. Biology of Reproduction 34, 145–158.CrossRefGoogle ScholarPubMed
Mitchell, AD, Scholz, AM, Mersmann, HJ 2001. Growth and body composition. In Biology of the pig (ed. WG Pond and HJ Mersmann), pp. 225–308. Cornell University Press, USA.Google Scholar
Ong, KKL, Ahmed, ML, Emmett, PM, Preece, MA, Dunger, DB 2000. Association between postnatal catch-up growth and obesity in childhood: prospective cohort study. British Medical Journal 320, 967–971.CrossRefGoogle ScholarPubMed
Ong, KKL, Preece, MA, Emmett, PM, Ahmed, ML, Dunger, DB 2002. Size at birth and early childhood growth in relation to maternal smoking, parity and infant breast-feeding: longitudinal birth cohort study and analysis. Pediatric Research 52, 863–867.CrossRefGoogle ScholarPubMed
Ong, KK, Petry, CJ, Emmett, PM, Sandhu, MS, Kiess, W, Hales, CN, Ness, AR, Dunger, DB, ALSPAC Study Team 2004. Insulin sensitivity and secretion in normal children related to size at birth, postnatal growth, and plasma insulin-like growth factor-1 levels. Diabetologia 47, 1064–1070.CrossRefGoogle Scholar
Phillips, DIW, Barker, DJP, Hales, CN, Hirst, S, Osmond, C 1994. Thinness at birth and insulin resistance in adult life. Diabetologia 37, 150–154.CrossRefGoogle ScholarPubMed
Poore, KR, Fowden, AL 2002. The effect of birth weight on glucose tolerance in pigs at 3 and 12 months of age. Diabetologia 45, 1247–1254.CrossRefGoogle ScholarPubMed
Poore, KR, Fowden, AL 2003. The effect of birth weight on hypothalamo-pituitary adrenal axis function in juvenile and adult pigs. Journal of Physiology 547, 107–116.CrossRefGoogle ScholarPubMed
Poore, KR, Fowden, AL 2004. Insulin sensitivity in juvenile and adult Large White pigs of low and high birthweight. Diabetologia 47, 340–348.CrossRefGoogle ScholarPubMed
Poore, KR, Forhead, AJ, Gardner, DS, Giussani, DA, Fowden, AL 2002. The effects of birth weight on basal cardiovascular function in pigs at 3 months of age. Journal of Physiology 539, 969–978.CrossRefGoogle ScholarPubMed
Roolan-Cachera, MF, Deheeger, M, Akrout, M, Bellisle, F 1995. Influence of macronutrients on adiposity development: a follow up study of nutrition and growth from 10 months to 8 years of age. International Journal of Obesity Related Metabolic Disorders 19, 573–578.Google Scholar
Simmons, D, Breier, BH 2002. Adult obesity and growth in childhood. British Medical Journal 324, 674.CrossRefGoogle ScholarPubMed
Sinclair-Smith, C, Dinsdale, F, Emery, J 1976. Evidence of duration and type of illness in children found unexpectedly dead. Archives of Diseases in Childhood 51, 424–429.CrossRefGoogle ScholarPubMed
van’t Hof, MA, Haschke, F 2000. Euro-Growth references for body mass index and weight for length, Euro-Growth Study Group. Journal of Pediatriatric Gastroenterology and Nutrition 31 (suppl. 1), S48–S59.CrossRefGoogle ScholarPubMed
Vanhala, M, Vanhala, P, Kumpusalo, E, Hadonen, P, Takala, J 1998. Relation between obesity from childhood to adulthood and the metabolic syndrome: population based study. British Medical Journal 317, 319–320.CrossRefGoogle ScholarPubMed
Walker, HM, Lev, J 1969. Elementary statistical methods, 3rd edition. Holt, Rinehart and Winston Inc, New York, pp. 52–74.Google Scholar
Wei, Y, He, X 2006. Discussion paper – conditional growth charts. Annals of Statistics 34, 2069–2097.CrossRefGoogle Scholar
Whittemore, C 1993. Reproduction. In The science and practice of pig production (ed. B Hill), pp. 123–125. Longman House Pub Longman Scientific and Technical, Harlow, Essex.Google Scholar
WHO Multicentre Growth Reference Study Group 2006. WHO Child Growth Standards based on length/height, weight and age. Acta Paediatrica 450 (suppl.), 76–85.Google Scholar
Widdowson, EM, McCance, RA 1975. A review: New thoughts on growth. Pediatric Research 9, 154–156.CrossRefGoogle ScholarPubMed
Wright, CM, Matthews, JNS, Waterston, A, Aynsley-Green, A 1994. What is a normal rate of weight gain in infancy? Acta Paediatrica 83, 351–356.CrossRefGoogle ScholarPubMed