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Liver metabolism traits in two rabbit lines divergently selected for intramuscular fat

Published online by Cambridge University Press:  26 October 2017

M. Martínez-Álvaro ,
Y. Paucar ,
K. Satué ,
A. Blasco  and
P. Hernández
M. Martínez-Álvaro
Affiliation:
Institute for Animal Science and Technology, Universitat Politècnica de València, 46022 Valencia, Spain
Y. Paucar
Affiliation:
Institute for Animal Science and Technology, Universitat Politècnica de València, 46022 Valencia, Spain
K. Satué
Affiliation:
Department of Animal Medicine and Surgery, Universidad Cardenal Herrera, 46113 Valencia, Spain
A. Blasco
Affiliation:
Institute for Animal Science and Technology, Universitat Politècnica de València, 46022 Valencia, Spain
P. Hernández*
Affiliation:
Institute for Animal Science and Technology, Universitat Politècnica de València, 46022 Valencia, Spain
*
†E-mail: [email protected]
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Abstract

Intramuscular fat (IMF) has a large effect in the sensory properties of meat because it affects tenderness, juiciness and flavour. A divergent selection experiment for IMF in longissimus dorsi (LD) muscle was performed in rabbits. Since liver is the major site of lipogenesis in rabbits, the objective of this work is to study the liver metabolism in the lines of the divergent selection experiment. Intramuscular fat content, perirenal fat weight, liver weight, liver lipogenic activities and plasma metabolites related to liver metabolism were measured in the eighth generation of selection. Direct response on IMF was 0.34 g/100 g of LD, which represented 2.7 SD of the trait, and selection showed a positive correlated response in the perirenal fat weight. High-IMF line showed greater liver size and greater liver lipogenic activities of enzymes glucose-6-phosphate dehydrogenase and malic enzyme. We did not find differences between lines for fatty acid synthase lipogenic activity. With regard to plasma metabolites, low-IMF line showed greater plasma concentration of triglycerides, cholesterol, bilirubin and alkaline phosphatase than high-IMF line, whereas high-IMF line showed greater albumin and alanine transaminase concentrations than low-IMF line. We did not observe differences between lines for glucose, total protein and plasma concentrations. Phenotypic correlations between fat (IMF and perirenal fat weight) and liver traits showed that liver lipogenesis affects fat deposition in both, muscle and carcass. However, the mechanisms whereby liver lipogenesis affected IMF content remain to be clarified.

Keywords

intramuscular fatlivermetabolismgenetic selectionrabbits
Type
Research Article
Information
animal , Volume 12 , Issue 6 , June 2018 , pp. 1217 - 1223
Copyright
© The Animal Consortium 2017 

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