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Impact of parity on bone metabolism throughout the reproductive cycle in sows

Published online by Cambridge University Press:  05 April 2016

M. M. J. van Riet ,
S. Millet ,
A. Liesegang ,
E. Nalon ,
B. Ampe ,
F. A. M. Tuyttens ,
D. Maes  and
G. P. J. Janssens
M. M. J. van Riet
Affiliation:
Animal Sciences Unit, Institute for Agricultural and Fisheries Research (ILVO), Scheldeweg 68, 9090 Melle, Belgium Department of Nutrition, Genetics and Ethology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
S. Millet*
Affiliation:
Animal Sciences Unit, Institute for Agricultural and Fisheries Research (ILVO), Scheldeweg 68, 9090 Melle, Belgium
A. Liesegang
Affiliation:
Institute of Animal Nutrition, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland Centre for Applied Biotechnology and Molecular Medicine, University of Zurich, 8057 Zurich, Switzerland
E. Nalon
Affiliation:
Animal Sciences Unit, Institute for Agricultural and Fisheries Research (ILVO), Scheldeweg 68, 9090 Melle, Belgium Department of Obstetrics, Reproduction and Herd Health, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
B. Ampe
Affiliation:
Animal Sciences Unit, Institute for Agricultural and Fisheries Research (ILVO), Scheldeweg 68, 9090 Melle, Belgium
F. A. M. Tuyttens
Affiliation:
Animal Sciences Unit, Institute for Agricultural and Fisheries Research (ILVO), Scheldeweg 68, 9090 Melle, Belgium Department of Nutrition, Genetics and Ethology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
D. Maes
Affiliation:
Department of Obstetrics, Reproduction and Herd Health, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
G. P. J. Janssens
Affiliation:
Department of Nutrition, Genetics and Ethology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
*
†E-mail: [email protected]
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Abstract

Bone metabolism fluctuates throughout the reproductive cycle of sows to enable foetal growth and milk production. Although increased bone mineralisation is conceivable in sows during reproduction, a study of mineralisation in function of parity has not been performed. This study evaluated the fluctuations of markers for bone metabolism in primiparous and multiparous sows throughout a reproductive cycle. The experiment included ten multiparous and five primiparous commercial hybrid sows from one herd. The sows were monitored for one reproductive cycle and fed according to commercial dietary standards. Blood samples were taken in the morning before feeding at fixed time intervals before (day -5) and during gestation (insemination (day 0), 21, 42, 63, 84), around parturition (day 108, 112, parturition (115), 118), and during lactation (day 122, 129, 143). Serum osteocalcin (OC) concentration increased in early and mid-gestation (P=0.002) and decreased at the end of gestation (P=0.001), whereas crosslaps (CTX) concentration decreased during early and mid-gestation (P=0.002) and increased towards the end of gestation (P=0.001). Towards the end of lactation serum levels of both markers increased (P=0.007 and 0.013, respectively). For hydroxyproline (HYP) no significant fluctuation in function of the reproductive cycle was detected. Matrix metalloproteinase 2 (MMP2) concentration increased towards parturition for both primiparous and multiparous sows (P=0.001), whereas during lactation no significant fluctuations in function of the reproductive cycle were found. A parity effect was found for OC and CTX (P<0.010), but not for the other markers. These results demonstrate that bone metabolism differed between primiparous and multiparous sows, although in both groups a similar fluctuation throughout the reproductive cycle was observed.

Keywords

sowbone mineralisationbone markersosteocalcincrosslaps
Type
Research Article
Information
animal , Volume 10 , Issue 10 , October 2016 , pp. 1714 - 1721
Copyright
© The Animal Consortium 2016 

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