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Effect of dietary sodium butyrate supplementation on growth, blood biochemistry, haematology and histomorphometry of intestine and immune organs of Japanese quail

Published online by Cambridge University Press:  18 October 2018

S. S. Elnesr Open the ORCID record for S. S. Elnesr [Opens in a new window] ,
A. Ropy  and
A. H. Abdel-Razik
S. S. Elnesr*
Affiliation:
Department of Poultry Production, Faculty of Agriculture, Fayoum University, 63514 Fayoum, Egypt
A. Ropy
Affiliation:
Department of Chemistry, Faculty of Science, Fayoum University, 63514 Fayoum, Egypt
A. H. Abdel-Razik
Affiliation:
Department of Histology, Faculty of Veterinary Medicine, Beni-Suef University, 62512 Beni-Suef, Egypt
*
†E-mail: [email protected]
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Abstract

New strategies must be developed to improve poultry performance and health. One of these strategies is the use of supplementations as sodium butyrate (SB) to improve the physiological status and then increasing the growth performance, but the best period of age in which the addition of SB is more effective on birds is not well understood. Therefore, the aim of this study was to investigate the effect of dietary inclusion of SB supplementation through the first, second or whole growth period on some physiological indices and growth performance of growing Japanese quail. In total, 240 unsexed 1-day-old quail chicks were divided into four groups (three replicates per group of 20 chicks in each). The first group was fed basal diet without SB from 1 to 42 days (control, T1), while SB at a rate of 1 g/kg basal diet was mixed with the feed of the 2nd, 3rd and 4th groups of chicks from 1 to 21 days (SB 1 to 21, T2), 1 to 42 days (SB 1 to 42, T3) and 22 to 42 days (SB 22 to 42, T4) of age, respectively. The results stated that addition of SB significantly improved live BW at 21 days, feed conversion ratio (FCR) and BW gain (BWG) during 1 to 21 days in T2 and T3 groups compared to T1 and T4 groups. During the whole period, group T3 had higher BWG and better FCR than the other groups (T1, T2 and T4). At 21 days, no significant differences among all treatments were detected on haematology and serum biochemistry except total protein and cholesterol. At 42 days, SB supplementation significantly improved most serum constituents, haematological parameters, villus height and width of intestine and morphometry of immune organs. The group fed SB throughout the experiment (T3) showed the best results. In conclusion, it is recommended feeding quail on diets containing SB through the whole growth period to show its affirmative impact on the growth and physiological indices.

Keywords

performancebiochemical profileshistologyphysiologypoultry
Type
Research Article
Information
animal , Volume 13 , Issue 6 , June 2019 , pp. 1234 - 1244
Copyright
© The Animal Consortium 2018 

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References

Abdelqader, A and Al-Fataftah, A 2016. Effect of dietary butyric acid on performance, intestinal morphology, microflora composition and intestinal recovery of heat-stressed broilers. Livestock Science 183, 78–83.Google Scholar
Ahsan, U, Cengiz, O, Raza, I, Kuter, E, Chacher, MFA, Iqbal, Z, Umar, S and Çakir, S 2016. Sodium butyrate in chicken nutrition: the dynamics of performance, gut microbiota, gut morphology, and immunity. World’s Poultry Science Journal 72, 265–275.Google Scholar
Association of Official Analytical Chemists 2006. Official methods of analysis, 18th edition. AOAC, Arlington, VA, USA.Google Scholar
Bancroft, JD and Marilyn, G 2008. The hematoxyline and eosin. In Theory and practice of histological techniques, 6th edition (ed. K Suvaran LCaB JDCL), pp. 121–134. Elsevier Health Sciences, London, UK.Google Scholar
Cerisuelo, A, Marín, C, Sánchez-Vizcaíno, F, Gómez, EA, de la Fuente, JM, Durán, R and Fernández, C 2014. The impact of a specific blend of essential oil components and sodium butyrate in feed on growth performance and Salmonella counts in experimentally challenged broilers. Poultry Science 93, 599–606.Google Scholar
Chamba, F, Puyalto, M, Ortiz, A, Torrealba, H, Mallo, JJ and Riboty, R 2014. Effect of partially protected sodium butyrate on performance, digestive organs, intestinal villi and E. coli development in broilers chickens. International Journal of Poultry Science 13, 390–396.Google Scholar
Constantoulakis, P, Papayannopoulou, T and Stamatoyannopoulos, G 1988. Alpha-amino-N-butyric acid stimulates fetal hemoglobin in the adult. Blood 72, 1961–1967.Google Scholar
Czerwiński, J, Højberg, O, Smulikowska, S, Engberg, RM and Mieczkowska, A 2012. Effects of sodium butyrate and salinomycin upon intestinal microbiota, mucosal morphology and performance of broiler chickens. Archives of Animal Nutrition 66, 102–116.Google Scholar
den Besten, G, van Eunen, K, Groen, AK, Venema, K, Reijngoud, DJ and Bakker, BM 2013. The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. Journal of Lipid Research 54, 2325–2340.Google Scholar
Dibner, JJ and Buttin, P 2002. Use of organic acids as a model to study the impact of gut microflora on nutrition and metabolism. Journal of Applied Poultry Research 11, 453–463.Google Scholar
El-Sawy, AF, El-Maddawy, ZK, Ibrahiem, HS and Bo-Ghazel, E 2015. The growth promoting effect of beta-glucan in comparison with sodium butyrate on broiler chicks. Alexandria Journal for Veterinary Sciences 44, 23–37.Google Scholar
Fushimi, T, Suruga, K, Oshima, Y, Fukiharu, M, Tsukamoto, Y and Goda, T 2006. Dietary acetic acid reduces serum cholesterol and triacylglycerols in rats fed a cholesterol-rich diet. British Journal of Nutrition 95, 916–924.Google Scholar
Gao, Z, Yin, J, Zhang, J, Ward, RE, Martin, RJ, Lefevre, M, Cefalu, WT and Ye, J 2009. Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes 58, 1509–1517.Google Scholar
Ge, H, Li, X, Weiszmann, J, Wang, P, Baribault, H, Chen, J, Tian, H and Li, Y 2008. Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids. Endocrinology 149, 4519–4526.Google Scholar
Guilloteau, P, Martin, L, Eeckhaut, V, Ducatelle, R, Zabielski, R and Van Immerseel, F 2010. From the gut to the peripheral tissue: the multiple effects of butyrate. Nutrition Research Reviews 23, 366–384.Google Scholar
Harr, KE 2002. Clinical chemistry of companion avian species: A review. Veterinary Clinical Pathology 31, 140–151.Google Scholar
Hodin, R 2000. Maintaining gut homeostasis: the butyrate-NF-kB connection. Gastroenterology 118, 798–801.Google Scholar
Hu, ZH and Guo, YM 2007. Effects of dietary sodium butyrate supplementation on the intestinal morphological structure, absorptive function and gut flora in chickens. Animal Feed Science and Technology 132, 240–249.Google Scholar
Jiang, Y, Zhang, W, Gao, F and Zhou, G 2015. Effect of sodium butyrate on intestinal inflammatory response to lipopolysaccharide in broiler chickens. Canadian Journal of Animal Science 95, 389–395.Google Scholar
Kamal, AM and Ragaa, NM 2014. Effect of dietary supplementation of organic acids on performance and serum biochemistry of broiler chicken. Nature and Science 12, 38–45.Google Scholar
Khatibjoo, A, Mahmoodi, M, Fattahnia, F, Akbari-Gharaei, M, Shokri, AN and Soltani, S 2018. Effects of dietary short-and medium-chain fatty acids on performance, carcass traits, jejunum morphology, and serum parameters of broiler chickens. Journal of Applied Animal Research 46, 492–498.Google Scholar
Kinoshita, M, Suzuki, Y and Saito, Y 2002. Butyrate reduces colonic paracellular permeability by enhancing PPAR gamma activation. Biochemical and Biophysical Research Communications 293, 827–831.Google Scholar
Leeson, S, Namkung, H, Antongiovanni, M and Lee, EH 2005. Effect of butyric acid on the performance and carcass yield of broiler chickens. Poultry Science 84, 1418–1422.Google Scholar
Le Poul, E, Loison, C, Struyf, S, Springael, JY, Lannoy, V, Decobecq, ME, Brezillon, S, Dupriez, V, Vassart, G, Van Damme, J and Parmentier, M 2003. Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. Journal of Biological Chemistry 278, 25481–25489.Google Scholar
Li, H, Gao, Z, Zhang, J, Ye, X, Xu, A, Ye, J and Jia, W 2012. Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3. Diabetes 61, 797–806.Google Scholar
Maiuolo, J, Oppedisano, F, Gratteri, S, Muscoli, C and Mollace, V 2016. Regulation of uric acid metabolism and excretion. International Journal of Cardiology 213, 8–14.Google Scholar
Mallo, JJ, Puyalto, M and Rama Rao, SV 2012. Evaluation of the effect of sodium butyrate addition to broilers diet on energy and protein digestibility, productive parameters and size of intestinal villi of animals. Feed and Livestock 8, 26–30.Google Scholar
Moquet, PCA, Onrust, L, Van Immerseel, F, Ducatelle, R, Hendriks, WH and Kwakkel, RP 2016. Importance of release location on the mode of action of butyrate derivatives in the avian get al. Importance of release location on the mode of action of butyrate derivatives in the avian gastrointestinal tract. World’s Poultry Science Journal 72, 61–80.Google Scholar
National Research Council (NRC) 1994. Nutrient requirements of poultry, 9th revised edition. National Academy Press, Washington, DC, USA.Google Scholar
Scholtz, N, Halle, I, Flachowsky, G and Sauerwein, H 2009. Serum chemistry reference values in adult Japanese quail (Coturnix coturnix japonica) including sex-related differences. Poultry Science 88, 1186–1190.Google Scholar
Shahir, MH, Moradi, S, Afsarian, O and Esmaeilipour, O 2013. Effects of cereal type, enzyme and sodiumbutyrate addition on growth performance, carcass traits and intestinal morphology of broilers. Brazilian Journal of Poultry Science 15, 169–286.Google Scholar
Sikandar, A, Zaneb, H, Younus, M, Masood, S, Aslam, A, Khattak, F, Ashraf, S, Yousaf, MS and Rehman, H 2017. Effect of sodium butyrate on performance, immune status, microarchitecture of small intestinal mucosa and lymphoid organs in broiler chickens. Asian-Australasian Journal of Animal Sciences 30, 690–699.Google Scholar
Wang, A, Wang, Y, Liao, XD, Wu, Y, Liang, JB, Laudadio, V and Tufarelli, V 2016. Sodium butyrate mitigates in vitro ammonia generation in cecal content of laying hens. Environmental Science and Pollution Research 23, 16272–16279.Google Scholar
Zhang, WH, Jiang, Y, Zhu, QF, Gao, F, Dai, SF, Chen, J and Zhou, GH 2011. Sodium butyrate maintains growth performance by regulating the immune response in broiler chickens. British Poultry Science 52, 292–301.Google Scholar
Zhou, ZY, Packialakshmi, B, Makkar, SK, Dridi, S and Rath, NC 2014. Effect of butyrate on immune response of a chicken macrophage cell line. Veterinary Immunology and Immunopathology 162, 24–32.Google Scholar