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Anionic salts and dietary 25-hydroxyvitamin D stimulate calcium availability in steers

Published online by Cambridge University Press:  19 October 2012

J. J. McGrath ,
D. B. Savage ,
J. V. Nolan ,
N. J. Rodgers  and
R. Elliott
J. J. McGrath*
Affiliation:
Environmental and Rural Science, University of New England, Armidale 2351, Australia
D. B. Savage
Affiliation:
Environmental and Rural Science, University of New England, Armidale 2351, Australia
J. V. Nolan
Affiliation:
Environmental and Rural Science, University of New England, Armidale 2351, Australia
N. J. Rodgers
Affiliation:
Environmental and Rural Science, University of New England, Armidale 2351, Australia
R. Elliott
Affiliation:
DSM Nutritional Products, Brisbane 4069, Australia
*
†E-mail: [email protected]
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Abstract

The influence of feeds containing varying dietary cation–anion differences (DCADs) with and without supplements of 25-hydroxyvitamin D (25(OH)D) on urine pH and excretion of macro minerals was determined in fistulated crossbred steers (mean live weight 315 ± 45 kg). A basal forage diet comprising lucerne hay and wheat chaff was used, to which varying quantities of MgCl2 or K2CO3 were added to achieve four levels of DCAD: −300, 50, 150 or 250 mEq/kg dry matter (DM). Steers were allocated to one of six treatments, one treatment for each diet and a further treatment for both the 50 and 150 mEq/kg DCAD diets, which were supplemented with 25(OH)D at a rate of 3 mg/steer per day. Urine pH from steers offered the diets comprising DCADs of 50, 150 and 250 mEq/kg ranging from 8.3 to 8.8. In treatments not containing 25(OH)D with DCADs of 50 to 250 mEq/kg, there were no significant differences in urine pH or Ca excretion. However, steers offered the diet with a DCAD of −300 mEq/kg DM produced urine with a significantly lower pH (6.5 to 7.5). Daily output of Ca in urine was also significantly higher from steers given this diet. Supplementation with 25(OH)D significantly increased urinary Ca excretion from steers offered diets of DCADs 50 and 150 mEq/kg DM. Estimates of daily urinary Ca excretion, calculated using the ratio of creatinine to Ca in ‘spot’ urine samples, were less variable than those based on total collection (residual mean square of 0.54 and 0.63, respectively).

Keywords

vitamin Dcalcium excretionDCADurine sampling
Type
Breeding and genetics
Information
animal , Volume 7 , Issue 3 , March 2013 , pp. 404 - 409
Copyright
Copyright © The Animal Consortium 2012

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References

Anderson, DL, Henderson, LJ 1986. Sealed chamber digestion for plant nutrient analysis. Agronomy Journal 78, 937–938.Google Scholar
Beck, N, Webster, S 1976. Effects of acute metabolic acidosis on parathyroid hormone action and calcium mobilization. American Journal of Physiology 230, 127–131.Google Scholar
Block, E 1984. Manipulating dietary anions and cations for prepartum dairy cows to reduce incidence of milk fever. Journal of Dairy Science 67, 2939–2948.Google Scholar
Block, E 1994. Manipulation of dietary cation–anion difference on nutritionally related production diseases, productivity, and metabolic responses of dairy-cows. Journal of Dairy Science 77, 1437–1450.Google Scholar
Breves, G, Schröder, B 1991. Comparative aspects of gastrointestinal phosphorus metabolism. Nutrition Research Reviews 4, 125–140.Google Scholar
Chen, XB, Gomes, MJ 1992. Estimation of Microbial protein supply to sheep and cattle based on urinary excretion of purine derivatives: an overview of technical details. In International Food Resources Unit, Occasional Publication Rowett Research Institute, Aberdeen, United Kingdom.Google Scholar
Chizzotti, ML, Valadares Filho, SdC, Valadares, RFD, Chizzotti, FHM, Tedeschi, LO 2008. Determination of creatinine excretion and evaluation of spot urine sampling in Holstein cattle. Livestock Science 113, 218–225.Google Scholar
Cho, YM, Choi, H, Hwang, IH, Kim, YK, Myung, KH 2006. Effects of 25-hydroxyvitamin D3 and manipulated dietary cation–anion difference on the tenderness of beef from cull native Korean cows. Journal of Animal Science 84, 1481–1488.Google Scholar
Christian, DG, Riche, AB, Yates, NE 2002. The yield and composition of switchgrass and coastal panic grass grown as a biofuel in Southern England. Bioresource Technology 83, 115–124.Google Scholar
DeGroot, MA, Block, E, French, PD 2010. Effect of prepartum anionic supplementation on periparturient feed intake, health, and milk production. Journal of Dairy Science 93, 5268–5279.Google Scholar
Ender, F, Dishington, IW, Helgebostad, A 1962. Parturient paresis and related forms of hypocalcemic disorders induced experimentally in dairy cows. Acta Veterinaria Scandinavica 3, 1–52.Google Scholar
Etheridge, RD, Pesti, GM, Foster, EH 1998. A comparison of nitrogen values obtained utilizing the Kjeldahl nitrogen and Dumas combustion methodologies (Leco CNS 2000) on samples typical of an animal nutrition analytical laboratory. Animal Feed Science and Technology 73, 21–28.Google Scholar
Fiske, CH, Subbarow, Y 1925. The colorimetric determination of phosphorus. Journal of Biological Chemistry 66, 375–400.Google Scholar
Fleischer, P, Metzner, M, Beyerbach, M, Hoedemaker, M, Klee, W 2001. The relationship between milk yield and the incidence of some diseases in dairy cows. Journal of Dairy Science 84, 2025–2035.CrossRefGoogle ScholarPubMed
Fredeen, AH, DePeters, EJ, Baldwin, RL 1988. Effects of acid-base disturbances caused by differences in dietary fixed ion balance on kinetics of calcium metabolism in ruminants with high calcium demand. Journal of Animal Science 66, 174–184.Google Scholar
Gaynor, PJ, Mueller, FJ, Miller, JK, Ramsey, N, Goff, JP, Horst, RL 1989. Parturient hypocalcemia in Jersey cows fed Alfalfa haylage-based diets with different cation to anion ratios. Journal of Dairy Science 72, 2525–2531.Google Scholar
GenStat 2008. GenStat for Windows, release 11.1, 11th edition. VSN International Ltd, Oxford.Google Scholar
Goff, JP, Horst, RL 2003. Role of acid-base physiology on the pathogenesis of parturient hypocalcaemia (milk fever) – the DCAD theory in principal and practice. Acta Veterinaria Scandinavica 97, 51–56.Google Scholar
Goff, JP, Horst, RL, Mueller, FJ, Miller, JK, Kiess, GA, Dowlen, HH 1991. Addition of chloride to a prepartal diet high in cations increases 1,25-dihydroxyvitamin D response to hypocalcemia preventing milk fever. Journal of Dairy Science 74, 3863–3871.Google Scholar
Hobson, W 1939. Urinary output of creatine and creatinine associated with physical exercise, and its relationship to carbohydrate metabolism. Biochemistry Journal 33, 1425–1429.Google Scholar
Hollis, BW, Conrad, HR, Hibbs, JW 1977. Changes in plasma 25-hydroxycholecalciferol and selected blood parameters after injection of massive doses of cholecalciferol of 25-hydroxycholecalciferol in non-lactating dairy cows. The Journal of Nutrition 107, 606–613.Google Scholar
Horst, RL 1986. Regulation of calcium and phosphorus homeostasis in the dairy cow. Journal of Dairy Science 69, 604–616.Google Scholar
Horst, RL, Goff, JP, Reinhardt, TA 1994. Calcium and vitamin D metabolism in the dairy cow. Journal of Dairy Science 77, 1936–1951.Google Scholar
Horst, RL, Goff, JP, Reinhardt, TA 2003. Role of Vitamin D in calcium homeostasis and its use in prevention of bovine periparturient paresis. Acta Veterinaria Scandinavica Supplement 97, 35–50.Google Scholar
Kurosaki, N, Yamato, O, Mori, F, Imoto, S, Maede, Y 2007. Preventive effect of mildly altering dietary cation–anion difference on milk fever in dairy cows. Journal of Veterinary Medical Science 69, 185–192.Google Scholar
Larsen, K 1972. Creatinine assay by a reaction-kinetic principle. Clinica Chimica Acta 41, 209–217.Google Scholar
Liesegang, A, Risteli, J 2005. Influence of different calcium concentrations in the diet on bone metabolism in growing dairy goats and sheep. Journal of Animal Physiology and Animal Nutrition 89, 113–119.Google Scholar
Lin, LI 1989. A concordance correlation coefficient to evaluate reproducibility. Biometrics 45, 255–268.Google Scholar
Luebbe, MK, Erickson, GE, Klopfenstein, TJ, Meyer, N 2009. Effect of dieatary cation–anion difference on intake and urinary pH in high concentrate diets. Nebraska Beef Report, pp. 94–95.Google Scholar
Mañas-Almendros, M, Ross, R, Care, AD 1982. Factors affection the secretion of phosphate in parotid saliva in the sheep and goat. Experimental Physiology 67, 269–280.Google Scholar
McGrath, J, Savage, D, Nolan, J 2011. Comparison of urine pH and Ca excretion of multiparous Holstein cows and Brangus steers in response to anionic salt supplementation. In Recent advances in animal nutrition (ed. P Cronje), pp. 141–142. University of New England, Armidale, NSW, Australia.Google Scholar
National Research Council (NRC) 2000. Nutrient Requirements of Beef Cattle. National Academy Press, Washington, DC.Google Scholar
Pehrson, B, Svensson, C, Gruvaeus, I, Virkki, M 1999. The influence of acidic diets on the acid–base balance of dry cows and the effect of fertilization on the mineral content of grass. Journal of Dairy Science 82, 1310–1316.CrossRefGoogle ScholarPubMed
Rowell, JG, Walters, RE 1976. Analysing data with repeated observations on each experimental unit. Journal of Agricultural Science 87, 423–432.Google Scholar
Rowling, MJ, Gliniak, C, Welsh, J, Fleet, JC 2007. High dietary vitamin D prevents hypocalcemia and osteomalacia in CYP27B1 knockout mice. The Journal of Nutrition 137, 2608–2615.Google Scholar
Schonewille, JT, Vantklooster, AT, Dirkzwager, A, Beynen, AC 1994. Stimulatory effect of an anion (chloride)-rich ration on apparent calcium absorption in dairy cows. Livestock Production Science 40, 233–240.Google Scholar
Scott, D, Beastall, G 1978. The effects of intravenous phosphate loading on salivary phosphate secretion and plasma parathyroid hormone levels in sheep. Experimental Physiology 63, 147–156.Google Scholar
Seifi, HA, Mohri, M, Zadeh, JK 2004. Use of pre-partum urine pH to predict the risk of milk fever in dairy cows. Veterinary Journal 167, 281–285.Google Scholar
Stern, J, Lewis, WHP 1957. The colorimetric estimation of calcium in serum with o-cresolphthalein complexone. Clinica Chimica Acta 2, 576–580.Google Scholar
Suda, T, Ueno, Y, Fujii, K, Shinki, T 2003. Vitamin D and bone. Journal of Cellular Biochemistry 88, 259–266.Google Scholar
Takagi, H, Block, E 1991. Effects of reducing dietary cation–anion balance on calcium kinetics in sheep. Journal of Dairy Science 74, 4225–4237.Google Scholar
Tucker, WB, Hogue, JF, Waterman, DE, Swenson, TS, Xin, Z, Hemken, RW, Jackson, JA, Adams, GD, Spicer, LJ 1991. Role of sulfur and chlorine in the dietary cation–anion balance equation for lactating dairy cattle. Journal of Animal Science 69, 1205–1213.Google Scholar
Waterman, DF, Swenson, TS, Tucker, WB, Hemken, RW 1991. Role of magnesium in the dietary cation–anion balance equation for ruminants. Journal of Dairy Science 74, 1866–1873.Google Scholar