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Maternal perinatal transfer of vitamins and trace elements to piglets

Published online by Cambridge University Press:  27 June 2019

J. J. Matte Open the ORCID record for J. J. Matte [Opens in a new window]  and
I. Audet
J. J. Matte*
Affiliation:
Sherbrooke Research and Development Centre, Agriculture and Agri-Food Canada, 2000 College Street, Sherbrooke, QC, J1M 0C8, Canada
I. Audet
Affiliation:
Sherbrooke Research and Development Centre, Agriculture and Agri-Food Canada, 2000 College Street, Sherbrooke, QC, J1M 0C8, Canada
*
†E-mail: [email protected]
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Abstract

Nursing piglets are entirely dependent, for their micronutrient provisions, upon in utero, colostrum and milk transfers from the dam. An adequate maternal transfer of micronutrients is all the more important during these periods which, in fact, lasts for approximately half the life cycle (conception to slaughter) of modern pigs. The present study aimed to set up a simple approach to assess the maternal perinatal transfer of vitamins and trace elements in sows. Prenatal transfer (R-u) was estimated as limited, passive or active using the ratio between pre-colostral serum concentrations of a given micronutrient in newborn piglets and corresponding pre-farrowing values in sows. Efficiency of the postnatal transfer (R-c) was estimated from the ratio between serum concentrations of post- and pre-colostral micronutrients in piglets. Data from literature (12 studies) were used for vitamins A, D, E, C, folic acid and B12, whereas vitamins B2, B3, B6 and B8 as well as Zn, Fe, Cu and Se were generated from a trial where blood sera from 20 sows, and their litter were collected during the perinatal period. In sow trial, statistical t tests were used to determine if ratios differed from 1. Prenatal transfer was active and in favour of piglets (R-u > 1, P < 0.03) for Zn and vitamins B6 and B8 (sow trial) as well as for vitamins C and B12 (literature data). This transfer was limited (R-u < 1, P < 0.01) for vitamin B2, Fe, Cu and Se (sow trial) and for vitamins A, E, D and folic acid (literature data) whereas it was passive for vitamin B3 (R-u = 1, P > 0.37). After birth, the early postnatal transfer through colostrum was active towards piglets for most micronutrients but vitamins B6 and B8 (R-c < 1, P < 0.01). Globally, the perinatal transfer (combination of R-u and R-c) was favourable to the neonatal piglets for most micronutrients except for vitamins A and D as well as Fe, Cu and Se whereas there is apparently a barrier for prenatal transfer which is not compensated by the colostrum provision to neonatal piglets. Then, post-colostral concentrations of these micronutrients in piglets remain below prenatal levels of their dam. Neonatal strategies of micronutrient provision are known for Fe (intramuscular injection) and Se (sow milk enrichment). Further studies are needed to assess the importance of the unfavourable perinatal transfer for Cu and vitamins A and D for piglet robustness later in life.

Keywords

colostrumlate gestationmicronutrientsneonatesow
Type
Research Article
Information
animal , Volume 14 , Issue 1 , January 2020 , pp. 31 - 38
Copyright
© Her Majesty the Queen in Right of Canada, as represented by the Minister of Agriculture and Agri-Food Canada 2019 

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References

Amundson, LA, Hernandez, LL and Crenshaw, TD 2017. Serum and tissue 25-OH vitamin D3 concentrations do not predict bone abnormalities and molecular markers of vitamin D metabolism in the hypovitaminosis D kyphotic pig model. British Journal of Nutrition 118, 30–40.CrossRefGoogle Scholar
Audet, I, Girard, CL, Lessard, M, Lo Verso, L, Beaudoin, F and Matte, JJ 2015. Homocysteine metabolism, growth performance, and immune responses in suckling and weanling piglets. Journal of Animal Science 93, 147–157.CrossRefGoogle ScholarPubMed
Barkow, B, Matte, JJ, Böhme, H and Flachowsky, G 2001. Influence of folic acid supplements on the carry-over of folates from the sow to the piglet. British Journal of Nutrition 85, 179–184.CrossRefGoogle ScholarPubMed
Bartol, FF and Bagnell, CA 2012. Lactocrine programming of female reproductive tract development: environmental connections to the reproductive continuum. Molecular and Cellular Endocrinology 354, 16–21.CrossRefGoogle ScholarPubMed
Braude, R, Chamberlain, AG, Kotarbinska, M and Mitchell, KG 1962. The metabolism of iron in piglets labeled iron either orally or by injection. British Journal of Nutrition 16, 427–449.CrossRefGoogle ScholarPubMed
Canadian Council on Animal Care 2009. Guide to the Care and Use of Experimental Animals. Canadian Council on Animal Care, Ottawa, ON, Canada.Google Scholar
Castellano, CA, Audet, I, Bailey, JL, Chouinard, PY, Laforest, JP and Matte, JJ 2010. Effect of dietary omega-3 fatty acids (fish oils) on boar reproduction and semen quality. Journal of Animal Science 88, 2346–2355.CrossRefGoogle ScholarPubMed
Combs, GF Jr. and McClung, JP 2017. The Vitamins. Fundamental Aspects in Nutrition and Health, 5th edition. Academic Press Elsevier, London, UK.Google Scholar
Cooper, DA, Berry, DA, Spendel, VA, Kiorpes, AL and Peters, JC 1997. The domestic pig as a model for evaluating olestra’s nutritional effects. Journal of Nutrition 127 (suppl. 8), 1555S–1565S.CrossRefGoogle ScholarPubMed
Csapò, J, Csapokiss, Z, Martin, TG and Hazas, Z 1995. Composition of sow’s colostrum and milk. Part 2. Fatty acid composition and content of fat, vitamins and macro- and microelements. Acta Alimentaria 24, 145–159.Google Scholar
Devillers, N, van Milgen, J, Prunier, A and Le Dividich, J 2004. Estimation of colostrum intake in the neonatal pig. Animal Science 78, 305–313.CrossRefGoogle Scholar
Fortier, ME, Audet, I, Giguère, A, Laforest, JP, Bilodeau, JF, Quesnel, H and Matte, JJ 2012. Effect of dietary organic and inorganic selenium on antioxidant status, embryo development and reproductive performance in hyperovulatory first-parity gilts. Journal of Animal Science 90, 231–240.CrossRefGoogle ScholarPubMed
Giguère, A, Fortier, MÈ and Matte, JJ 2005. Rapid, sensitive and versatile determination of selenium in different biological samples. Canadian Journal of Animal Science 85, 533–536.CrossRefGoogle Scholar
Giguère, A, Girard, CL and Matte, JJ 2002. Erythrocyte glutathione reductase activity and riboflavin nutritional status in early-weaned piglets. International Journal of Vitamin and Nutrition Research 72, 383–387.CrossRefGoogle ScholarPubMed
Goff, JP, Horst, RL and Littledike, ET. 1984. Effect of sow vitamin D status at parturition on the vitamin D status of neonatal piglets. Journal of Nutrition 114, 163–169.CrossRefGoogle ScholarPubMed
Gomez-Garcia, GG and Matrone, G 1967. Copper metabolism in the early postnatal period of the piglet. Journal of Nutrition 92, 237–244.CrossRefGoogle ScholarPubMed
Gondret, F, Lefaucheur, L, Louveau, L, Lebret, B, Pichodo, X and Le Cozler, Y 2005. Influence of piglet birth weight on postnatal growth performance, tissue lipogenic capacity and muscle histological traits at market weight. Livestock Production Science 93, 137–146.Google Scholar
Håkansson, J, Hakkarainen, J and Lundeheim, N 2001. Variation in vitamin E, glutathione peroxidase and retinol concentrations in blood plasma of primiparous sows and their piglets, and in vitamin E, selenium and retinol contents in sows’ milk. Acta Agricultura Scandinavica A Animal Science 51, 224–234.Google Scholar
Kim, JG and Vallet, JL 2007. Placental expression of the membrane form of folate binding protein during pregnancy in swine. Theriogenology 67, 1279–1284.CrossRefGoogle ScholarPubMed
Kolp, E, Wilkens, MR, Pendl, W, Eichenberger, B and Liesegang, A 2017. Vitamin D metabolism in growing pigs: influence of UVB irradiation and dietary vitamin D supply on calcium homeostasis, its regulation and bone metabolism. Journal of Animal Physiology and Animal Nutrition 101 (suppl. 1), 79–94.CrossRefGoogle ScholarPubMed
Lauridsen, C and Matte, JJ 2017. Recent advances in understanding the role of vitamins in pig. In Achieving sustainable production of pig meat Volume 2: Animal breeding and nutrition (ed. Wiseman, J.), pp. 165–184. Burleigh Dodds Science Publishing, Cambridge, UK.CrossRefGoogle Scholar
Linderkamp, O, Betke, K, Güntner, M, Jap, GH, Riegel, KP and Walser, K 1981. Blood volume in newborn piglets: effects of time of natural cord rupture, intra-uterine growth retardation, asphyxia, and prostaglandin-induced prematurity. Pediatric Research 15, 53–57.CrossRefGoogle ScholarPubMed
Loudenslager, MJ, Ku, PK, Whetter, PA, Ullrey, DE, Whitehair, CK, Stowe, HD and Miller, ER 1986. Importance of diet of dam and colostrum to the biological antioxidant status and parenteral iron tolerance of the pig. Journal of Animal Science 63, 1905–1914.CrossRefGoogle ScholarPubMed
Mahan, DC 2000. Effect of organic and inorganic selenium sources and levels on sow colostrum and milk selenium content. Journal of Animal Science 78, 100–105.CrossRefGoogle ScholarPubMed
Mahan, DC and Vallet, JL 1997. Vitamin and mineral transfer during fetal development and the early postnatal period in pigs. Journal of Animal Science 75, 2731–2738.CrossRefGoogle ScholarPubMed
Mahan, DC, Watts, MR and St-Pierre, N. 2009. Macro- and micromineral composition of fetal pigs and their accretion rates during fetal development. Journal of Animal Science. 87, 2823–2832.CrossRefGoogle ScholarPubMed
Matte, JJ, Audet, I and Girard, CL. 2014. The perinatal transfer of vitamins and trace elements from sows to piglets. Journal of Animal Science 92 (suppl. 2), 153.Google Scholar
Matte, JJ, Audet, I, Ouattara, B, Bissonnette, N, Talbot, G, Lapointe, J, Guay, F, Lo Verso, L and Lessard, M. 2017a. Effets des sources et voies d’administration du cuivre et des vitamines A et D sur le statut postnatal de ces micronutriments chez les porcelets sous la mère. Journées de la Recherche Porcine en France 49, 69–74.Google Scholar
Matte, JJ and Girard, CL 1989. Effects of intramuscular injections of folic acid during lactation on folates in serum and milk and performance of sows and piglets. Journal of Animal Science 67, 426–431.CrossRefGoogle ScholarPubMed
Matte, JJ and Girard, CL 1996. Changes of serum and blood volumes during gestation and lactation in multiparous sows. Canadian Journal of Animal Science 76, 263–266.CrossRefGoogle Scholar
Matte, JJ, Girard, CL and Guay, F 2017b. Intestinal fate of dietary zinc and copper: postprandial net fluxes of these trace elements in portal vein of pigs. Journal of Trace Elements in Medicine and Biology 44, 65–70.CrossRefGoogle ScholarPubMed
Matte, JJ and Lauridsen, C 2013. Vitamins and vitamin utilization in swine. In Sustainable Swine Nutrition (ed. Chiba, L.), pp. 139–172. John Wiley & Sons Inc., Ames, IA, USA.Google Scholar
Matte, JJ, Ponter, AA and Sève, B 1997. Effects of chronic parenteral pyridoxine and acute enteric tryptophan on pyridoxine status, glycemia and insulinemia stimulated by enteric glucose in weanling piglets. Canadian Journal of Animal Science 77, 663–668.CrossRefGoogle Scholar
National Research Council (NRC) 2012. Nutrient requirements of swine, 11th revised edition. National Academy Press, Washington, DC, USA.Google Scholar
Père, M-C 2003. Materno-foetal exchanges and utilisation of nutrients by the foetus: comparison between species. Reproduction Nutrition Development 43, 1–15.CrossRefGoogle ScholarPubMed
Peters, JC, Mahan, DC, Wiseman, TG and Fastinger, ND 2010. Effect of dietary organic and inorganic micromineral source and level on sow body, liver, colostrum, mature milk, and progeny mineral composition over six parities. Journal of Animal Science 88, 626–637.Google Scholar
Pinelli-Saavedra, A, de la Barca, AMC, Hernandez, J, Valenzuela, R and Scaife, JR. 2008. Effect of supplementing sows’ feed with alpha-tocopherol acetate and vitamin C on transfer of alpha-tocopherol to piglet tissues, colostrum and milk: aspects of immune status of piglets. Research in Veterinary Science 85, 92–100.CrossRefGoogle ScholarPubMed
Pinelli-Saavedra, A and Scaife, JR 2005. Pre- and postnatal transfer of vitamins E and C to piglets in sows supplemented with vitamin E and vitamin C. Livestock Production Science 97, 231–240.CrossRefGoogle Scholar
Pond, WG and Maner, JH 1984. Lactation. In Swine Production and Nutrition, pp. 147–155. The AVI Publishing Company Inc., Wesport, CT, USA.CrossRefGoogle Scholar
Pownall, R and Dalton, RG 1973. Blood and plasma volumes of neonatal pigs expressed relative to bodyweight and total body water. British Veterinary Journal 129, 583–588.CrossRefGoogle ScholarPubMed
Quesnel, H, Brossard, L, Valancogne, A and Quiniou, N 2008a. Influence of some sow characteristics on within-litter variation of piglet birth weight. Animal 2, 1842–1849.Google ScholarPubMed
Quesnel, H, Renaudin, A, Le Floc’h, N, Jondreville, C, Père, M-C, Taylor-Pickard, JA and Le Dividich, J 2008b. Effect of organic and inorganic selenium sources in sow diets on colostrum production and piglet response to a poor sanitary environment after weaning. Animal 2, 859–866.CrossRefGoogle ScholarPubMed
Ramirez, CG, Miller, ER, Ullrey, DE and Hoefer, JA 1963. Swine hematology from birth to maturity. III. Blood volume of the nursing pig. Journal of Animal Science 22, 1068–1074.CrossRefGoogle Scholar
Ramsay, TG, Karousis, J, White, ME and Wolverton, CK 1991. Fatty acid metabolism by the porcine placenta. Journal of Animal Science 69, 3645–3654.CrossRefGoogle ScholarPubMed
Santschi, DE, Berthiaume, R, Matte, JJ, Mustafa, AF and Girard, CL 2005. Fate of supplementary B-vitamins in the gastrointestinal tract of dairy cows. Journal of Dairy Science 88, 2043–2054.CrossRefGoogle ScholarPubMed
Schweigert, FJ, Rosival, I, Rambeck, WA and Gropp, J 1995. Plasma transport and tissue distribution of [C-14]beta-carotene and [H-3]retinol administered orally to pigs. International Journal of Vitamin and Nutrition Research 65, 95–100.Google Scholar
Simard, F, Guay, F, Girard, CL, Giguère, A, Laforest, JP and Matte, JJ 2007. Effects of concentrations of cyanocobalamin in the gestation diet on some criteria of vitamin B-12 metabolism in first-parity sows. Journal of Animal Science 85, 3294–3302.CrossRefGoogle ScholarPubMed
Yen, JT and Pond, WG, 1983. Response of swine to periparturient vitamin C supplementation. Journal of Animal Science 56, 621–624.CrossRefGoogle ScholarPubMed