Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-26T14:07:11.876Z Has data issue: false hasContentIssue false

Effects of feeding dry propylene glycol to early postpartum Holstein dairy cows on production and blood parameters

Published online by Cambridge University Press:  01 October 2009

Y.-H. Chung
Affiliation:
Department of Dairy and Animal Science, The Pennsylvania State University, University Park, PA 16802, USA
I. D. Girard
Affiliation:
Probiotech International Inc., Saint-Hyacinthe, QC, Canada
G. A. Varga*
Affiliation:
Department of Dairy and Animal Science, The Pennsylvania State University, University Park, PA 16802, USA
*
Get access

Abstract

In all, 18 multiparous and 19 primiparous Holstein dairy cows were used in a completely randomized design with restrictions to evaluate the effects of feeding propylene glycol (PG) as a dry product, via two delivery methods, on production and blood parameters. PG treatments were administered from parturition through 21 days postpartum. Treatments were: (i) control, no PG; (ii) top dress, 162.5 g PG/day by top dressing onto the total mixed ration (TMR) and; (iii) mixing, 162.5 g PG/day as a part of the TMR by incorporating it into the TMR. PG used was a dry product which contained 65% pure PG and 35% silicon dioxide as the dry carrier. Coccygeal blood was sampled on 4, 7, 14 and 21 days in milk (±1.50 pooled s.d.). Supplementation of dry PG by top dressing onto, or incorporating into, the TMR had no effects on average dry matter intake, milk yield and composition, serum insulin, serum and plasma metabolites and milk ketones. Concentrations of urine ketones tended (P = 0.10) to be reduced by PG supplementation from 41.5 to 15.2 mg/dl. Supplementation of PG tended (P = 0.07) to decrease the incidence for subclinical ketosis from 39% to 24% and 13% for cows fed a TMR supplemented with no dry PG, with dry PG as a top dress and dry PG as a part of the TMR, respectively. It is concluded that supplementing PG as a dry product via incorporating into the TMR is as effective as when used as a top dress, based on the efficacies of both delivery methods to numerically reduce urine ketones concentrations and, therefore, the incidence for subclinical ketosis during the first 21 days of lactation. However, it should be noted that the number of cows used in the current study was minimal, and more cows are needed to confirm the efficacy of supplementing PG as a dry product on reducing the prevalence of subclinical ketosis in dairy cows during the first month of lactation.

Type
Full Paper
Copyright
Copyright © The Animal Consortium 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Association of Official Analytical Chemists 2005. Official methods of analysis, 18th edition. AOAC Int., Gaithersburg, MD, USA.Google Scholar
Brockman, RP, Laarveld, B 1986. Hormonal regulation of metabolism in ruminants: a review. Livestock Production Science 14, 313334.CrossRefGoogle Scholar
Bryant, TC, Rivera, JD, Galyean, ML, Duff, GC, Hallford, DM, Montgomery, TH 1999. Effects of dietary level of ruminally protected choline on performance and carcass characteristics of finishing beef steers and on growth and serum metabolites in lambs. Journal of Animal Science 77, 28932903.Google Scholar
Carrier, J, Stewart, S, Godden, S, Fetrow, J, Rapnicki, P 2004. Evaluation and use of three cowside tests for detection of subclinical ketosis in early postpartum cows. Journal of Dairy Science 87, 37253735.Google Scholar
Christensen, JO, Grummer, RR, Rasmussen, FE, Bertics, SJ 1997. Effect of method of delivery of propylene glycol on plasma metabolites of feed-restricted cattle. Journal of Dairy Science 80, 563568.CrossRefGoogle ScholarPubMed
Clapperton, JL, Czerkawski, JW 1972. Metabolism of propane-1:2-diol infused into the rumen of sheep. British Journal of Nutrition 27, 553560.CrossRefGoogle ScholarPubMed
Crocker, CL 1967. Rapid determination of urea nitrogen in serum or plasma without deproteinization. American Journal of Medical Technology 33, 361365.Google ScholarPubMed
Duffield, TF, Sandals, D, Leslie, KE, Lissemore, K, McBride, BW, Lumsden, JH, Dick, P, Bagg, R 1998. Efficacy of monensin for the prevention of subclinical ketosis in lactating dairy cows. Journal of Dairy Science 81, 28662873.CrossRefGoogle ScholarPubMed
Fisher, LJ, Erfle, JD, Sauer, FD 1971. Preliminary evaluation of the addition of glucogenic materials to the rations of lactating cows. Canadian Journal of Animal Science 51, 721727.CrossRefGoogle Scholar
Grummer, RR, Winkler, JC, Bertics, SJ, Studer, VA 1994. Effect of propylene glycol dosage during feed restriction on metabolites in blood of prepartum Holstein heifers. Journal of Dairy Science 77, 36183623.CrossRefGoogle ScholarPubMed
Heimberg, M, Wilcox, HG, Dunn, GD, Woodside, WF, Breen, KJ, Soler-Argilaga, C 1974. Regulation of hepatic metabolism. In Proceedings of the Alfred Benzon Symposium VI (ed. F Lindquist and N Tygstrup), pp. 119143. Academic Press, New York, USA.Google Scholar
Herdt, TH, Emery, RS 1992. Therapy of diseases of ruminant intermediary metabolism. The Veterinary clinics of North America. Food Animal Practice 8, 91106.Google Scholar
Hoedemaker, M, Prange, D, Zerbe, H, Frank, J, Daxenberger, A, Meyer, HHD 2004. Peripartal propylene glycol supplementation and metabolism, animal health, fertility, and production in dairy cows. Journal of Dairy Science 87, 21362145.CrossRefGoogle ScholarPubMed
Hutjens, MF 1996. Practical approaches to feeding the high producing cow. Animal Feed Science and Technology 59, 199206.CrossRefGoogle Scholar
Johnson, RB 1954. The treatment of ketosis with glycerol and propylene glycol. The Cornell Veterinarian 44, 621.Google ScholarPubMed
Johnson, MM, Peters, JP 1993. Technical note: an improved method to quantify nonesterified fatty acids in bovine plasma. Journal of Animal Science 71, 753756.Google Scholar
Juchem, SO, Santos, FA, Imaizumi, H, Pires, AV, Barnabe, EC 2004. Production and blood parameters of Holstein cows treated prepartum with sodium monensin or propylene glycol. Journal of Dairy Science 87, 680689.CrossRefGoogle ScholarPubMed
Kenward, MG, Roger, JH 1997. Small sample inference for fixed effects from restricted maximum likelihood. Biometrics 53, 983997.CrossRefGoogle ScholarPubMed
Kristensen, NB, Danfaer, A, Rojen, BA, Raun, BM, Weisbjerg, MR, Hvelplund, T 2002. Metabolism of propionate and 1,2-propanediol absorbed from the washed reticulorumen of lactating cows. Journal of Animal Science 80, 21682175.Google Scholar
Kristensen, NB, Raun, BM 2007. Ruminal and intermediary metabolism of propylene glycol in lactating Holstein cows. Journal of Dairy Science 90, 47074717.Google Scholar
Kronfeld, DS 1965. Plasma non-esterified fatty acid concentrations in the dairy cow: responses to nutritional and hormonal stimuli, and significance in ketosis. The Veterinary Record 77, 3035.Google ScholarPubMed
LeBlanc, SJ, Leslie, KE, Duffield, TF 2005. Metabolic predictors of displaced abomasum in dairy cattle. Journal of Dairy Science 88, 159170.CrossRefGoogle ScholarPubMed
Littell, RC, Henry, PR, Ammerman, CB 1998. Staristical analysis of repeated measures data using SAS procedures. Journal of Animal Science 76, 12161231.CrossRefGoogle ScholarPubMed
Littell, RC, Milliken, GA, Stroup, WW, Wolfinger, RD 1996. SAS® system for mixed models. SAS Institute Inc., Cary, NC, USA.Google Scholar
Manns, JG, Boda, JM 1967. Insulin release by acetate, propionate, butyrate, and glucose in lambs and adult sheep. American Journal of Physiology 212, 747755.Google Scholar
Manns, JG, Boda, JM, Willes, RF 1967. Probable role of propionate and butyrate in control of insulin secretion in sheep. American Journal of Physiology 212, 756764.Google Scholar
Marsh, WH, Fingerhut, B, Miller, H 1965. Automated and manual direct methods for the determination of blood urea. Clinical Chemistry 11, 624627.Google Scholar
National Research Council 2001. Nutrient requirements of dairy cattle, 7th revised edition. National Academy of Sciences, Washington, DC, USA.Google Scholar
Patton, RS, Sorenson, CE, Hippen, AR 2004. Effects of dietary glucogenic precursors and fat on feed intake and carbohydrate status of transition dairy cows. Journal of Dairy Science 87, 21222129.CrossRefGoogle ScholarPubMed
Pickett, MM, Piepenbrink, MS, Overton, TR 2003. Effects of propylene glycol or fat drench on plasma metabolites, liver composition, and production of dairy cows during the periparturient period. Journal of Dairy Science 86, 21132121.Google Scholar
Raun, BML, Kristensen, NB, Harmon, DL 2004. Splanchnic metabolism of propylene glycol infused into the jugular vein of steers under washed rumen conditions. Journal of Animal and Feed Science 13 (suppl. 1), 331334.Google Scholar
SAS Institute 1999. SAS/STAT user’s guide: statistics. Version 8 ed. SAS Institute Inc., Cary, NC, USA.Google Scholar
Sauer, FD, Erfle, JD, Fisher, LJ 1973. Propylene glycol and glycerol as a feed additive for lactating dairy cows: an evaluation of blood metabolite parameters. Canadian Journal of Animal Science 53, 265271.CrossRefGoogle Scholar
Van Soest, PJ, Robertson, JB, Lewis, BA 1991. Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. Journal of Dairy Science 74, 35833597.CrossRefGoogle ScholarPubMed
Studer, VA, Grummer, RR, Bertics, SJ, Reynolds, CK 1993. Effect of prepartum propylene glycol administration on periparturient fatty liver in dairy cows. Journal of Dairy Science 76, 29312939.Google Scholar
Trinder, P 1969. Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Annals of Clinical Biochemistry 6, 2427.CrossRefGoogle Scholar
Waldo, DR, Schultz, LH 1960. Blood and rumen changes following the intra-ruminal administration of glycogenic materials. Journal of Dairy Science 43, 496505.Google Scholar
West, CE, Passey, RF 1967. Effect of glucose load and of insulin on the metabolism of glucose and of palmitate in sheep. Biochemical Journal 102, 5864.CrossRefGoogle Scholar
Wildman, EE, Jones, GM, Wagner, PE, Boman, RL, Jr.Troutt, HF, Lesch, TN 1982. A dairy cow body condition scoring system and its relationship to selected production characteristics. Journal of Dairy Science 65, 495501.CrossRefGoogle Scholar
Williamson, DH, Mellanby, J, Krebs, HA 1962. Enzymic determination of d(-)-beta-hydroxybutyric acid and acetoacetic acid in blood. Biochemical Journal 82, 9096.Google Scholar