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The effect of nutrition and metabolic status on the development of follicles, oocytes and embryos in ruminants

Published online by Cambridge University Press:  28 April 2014

J. Dupont ,
R. J. Scaramuzzi  and
M. Reverchon
J. Dupont*
Affiliation:
INRA, UMR85 Physiologie de la Reproduction et des Comportements, F-37380 Nouzilly, France CNRS, UMR6175 Physiologie de la Reproduction et des Comportements, F-37380 Nouzilly, France Université François Rabelais de Tours, F-37041 Tours, France IFCE, F-37380 Nouzilly, France
R. J. Scaramuzzi
Affiliation:
INRA, UMR85 Physiologie de la Reproduction et des Comportements, F-37380 Nouzilly, France Department of Comparative Biomedical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mimms, Hertfordshire AL9 7TA, UK
M. Reverchon
Affiliation:
INRA, UMR85 Physiologie de la Reproduction et des Comportements, F-37380 Nouzilly, France CNRS, UMR6175 Physiologie de la Reproduction et des Comportements, F-37380 Nouzilly, France Université François Rabelais de Tours, F-37041 Tours, France IFCE, F-37380 Nouzilly, France
*
†E-mail: [email protected]
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Abstract

The impact of nutrition and energy reserves on the fertility of ruminants has been extensively described. However, the metabolic factors and the molecular mechanisms involved in the interactions between nutrition and ovarian function are still poorly understood. These factors could be hormonal (either reproductive and/or metabolic) and/or dietary and metabolic (glucose, amino acids and fatty acids). In this review, we briefly summarize the impact of those nutrients (fatty acids, glucose and amino acids) and metabolic hormones (insulin/IGF-I, growth hormone, T3/4, ghrelin, apelin and the adipokines (leptin, adiponectin and resistin)) implicated in the development of ovarian follicles, oocytes and embryos in ruminants. We then discuss the current hypotheses on the mechanisms of action of these factors on ovarian function. We particularly describe the role of some energy sensors including adenosine monophosphate-activated kinase and peroxisome proliferator-activated receptors in the ovarian cells.

Keywords

nutrientsmetabolic hormonesovarymechanism of actionruminant
Type
Full Paper
Information
animal , Volume 8 , Issue 7 , July 2014 , pp. 1031 - 1044
Copyright
© The Animal Consortium 2014 

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