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Evaluation of Zoletil and other injectable anaesthetics for field sedation of brushtail possums (Trichosurus vulpecula)

Published online by Cambridge University Press:  01 January 2023

DR Morgan ,
S Scobie  and
DG Arthur
DR Morgan*
Affiliation:
Landcare Research, PO Box 40, Lincoln 7640, New Zealand
S Scobie
Affiliation:
Landcare Research, PO Box 40, Lincoln 7640, New Zealand
DG Arthur
Affiliation:
Selwyn-Rakaia Veterinary Services, PO Box 52, Dunsandel 7657, New Zealand
*
* Contact for correspondence and requests for reprints: [email protected]
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Abstract

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Ketamine has been used for many years for sedating possums captured in the wild in New Zealand, but its recent reclassification as a Class III drug under the Misuse of Drugs Act (1975) has made its continued use impractical. Consequently, four other injectable anaesthetic compounds (Zoletil, xylazine-butorphanol, medetomidine-butorphanol and Fentazin) were evaluated as replacements for ketamine. Zoletil (a combination of zolazepam and tiletamine) was the only effective alternative. Brushtail possums (Trichosurus vulpecula) were sedated adequately for general procedures, such as fitting radio-collars, at an intramuscular dose of 5 mg kg−1. At this dose, possums were sedated on average in 3.6 min, and recovery took 65 min on average. Zoletil did not cause sudden arousal as seen with some other anaesthetics, but most possums showed involuntary chewing during recovery, and in some cases excessive salivation. In contrast, Fentazin and combinations of xylazine-butorphanol and medetomidine-butorphanol failed to produce sedation at doses known to be effective in other mammalian species. Zoletil proved similar to ketamine in both performance and cost, and is therefore recommended as a cost-effective anaesthetic and humane method for sedating possums captured in the wild.

Keywords

anaestheticsanimal welfarebrushtail possumsedationwildlife captureZoletil
Type
Research Article
Information
Animal Welfare , Volume 21 , Issue 4 , November 2012 , pp. 457 - 462
Copyright
© 2012 Universities Federation for Animal Welfare

References

Arnemo, JM and SØli, NE 1992 Immobilization of mink (Mustela vison) with medetomidine-ketamine and remobilization with atipamezole. Veterinary Research Communications 16: 281–292CrossRefGoogle ScholarPubMed
Bartram, DH, Diamond, MJ, Tute, AS, Trafford, AW and Jones, RS 1994 Use of medetomidine and butorphanol for sedation in dogs. Journal of Small Animal Practice 35: 495–498. http://dx.doi.org/10.1111/j.1748-5827.1994.tb03795.xCrossRefGoogle Scholar
Creed, KE and McDonald, IR 1970 Salivary secretory potentials in the marsupial Trichosurus vulpecula. Comparative and General Pharmacology 1: 285–292. http://dx.doi.org/10.1016/0010-4035(70)90022-4CrossRefGoogle ScholarPubMed
Degerfeld, M 2005 Personal experiences in the use of Zoletil® for anaesthesia of the red-necked wallaby (Macropus rufogriseus). Veterinary Research Communications 29: 297–300. http://dx.doi.org/10.1007/s11259-005-0066-5CrossRefGoogle Scholar
Diehl, KH, Hull, R, Morton, D, Pfister, R, Rabemampianina, Y, Smith, D, Vidal, JM and Vorstenbosch, CVD 2001 A good practice guide to the administration of substances and removal of blood, including routes and volumes. Journal of Applied Toxicology 21: 15–23. http://dx.doi.org/10.1002/jat.727CrossRefGoogle Scholar
Duckworth, JA and Meikle, LM 1995 The common brushtail possum. Australian and New Zealand Council for the Care of Animals in Research and Teaching News 8: 4–8Google Scholar
English, MJM, Papenberg, R, Farias, E, Scott, WAC and Hinchey, J 1991 Heat-loss in an animal experimental-model. Journal of Trauma-Injury Infection and Critical Care 3: 36–38. http://dx.doi.org/10.1097/00005373-199101000-00008CrossRefGoogle Scholar
Fowler, M 1995 Restraint and Handling of Wild and Domestic Animals. lowa State University Press: Ames, IA, USAGoogle Scholar
Geiser, DR and Henton, JE 1988 Xylazine and butorphanol: survey of field use in the horse. Veterinary Clinics of North America: Equine Practice 10(1): 7–11Google Scholar
Greene, SA and Thurmon, JC 1988 Xylazine: a review of its pharmacology and use in veterinary medicine. Journal of Veterinary Pharmacology and Therapeutics 11: 295–313. http://dx.doi.org/10.1111/j.1365-2885.1988.tb00189.xCrossRefGoogle ScholarPubMed
Holz, P 1992 Immobilization of marsupials with tiletamine and zolazepam. Journal of Zoo and Wildlife Medicine 23: 426–428Google Scholar
Hufschmid, J, Handasyde, KA and Beveridge, I 2010 The role of host and environmental factors in the epidemiology of rump-wear in brushtail possums. Australian Journal of Zoology 58: 250–262. http://dx.doi.org/10.1071/ZO10030CrossRefGoogle Scholar
IVS 2011 IVS Annual 2011. The New Zealand Index of Veterinary Specialities Annual. CMPMedica (NZ) Ltd: North Shore City, New ZealandGoogle Scholar
Jacobson, C 2001 A novel anaesthetic regimen for surgical procedures in guinea pigs. Lab Animals 35: 271–276. http://dx.doi.org/10.1258/0023677011911598CrossRefGoogle Scholar
King, WJ, Wilson, ME, Allen, T, Festa-Bianchet, M and Coulson, G 2011 A capture technique for free-ranging eastern grey kangaroos (Macropus giganteus) habituated to humans. Australian Mammalogy 33: 47–51. http://dx.doi.org/10.1071/AM10029CrossRefGoogle Scholar
Ko, J, Villarreal, A, Kuo, W and Nicklin, C 1998 Evaluation of sedative and cardiorespiratory effects of diazepam-butorphanol, acepromazine-butorphanol, and xylazine-butorphanol in ferrets. Journal of the American Animal Hospital Association 34: 242–250CrossRefGoogle ScholarPubMed
Kreeger, T, Mandsager, R, Seal, U, Callahan, M and Beckel, M 1989 Physiological response of gray wolves to butorphanolxylazine immobilization and antagonism by naloxone and yohimbine. Journal of Wildlife Diseases 25: 89–94CrossRefGoogle ScholarPubMed
Kreeger, T, Seal, U, Callahan, M and Beckel, M 1990 Physiological and behavioral responses of gray wolves (Canis lupus) to immobilization with tiletamine and zolazepam. Journal of Wildlife Diseases 26: 90–94CrossRefGoogle ScholarPubMed
Massolo, A, Sforzi, A and Lovari, S 2003 Chemical immobilization of crested porcupines with tiletamine HCl and zolazepam HCl (Zoletil) under field conditions. Journal of Wildlife Diseases 39: 727–731CrossRefGoogle ScholarPubMed
McDowell, A, McLeod, BJ, Rades, T and Tucker, IG 2009 Polymeric nanoparticles as an oral delivery system for biocontrol agents for the brushtail possum (Trichosurus vulpecula). New Zealand Veterinary Journal 57: 370–377. http://dx.doi.org/10.1080/00480169.2009.64731CrossRefGoogle ScholarPubMed
Montague, TL 2000 The Brushtail Possum: Biology, Impact and Management of an Introduced Marsupial. Manaaki Whenua Press: Lincoln, New ZealandGoogle Scholar
Pitt, J, Lariviere, S and Messier, FO 2006 Efficacy of Zoletil® for field immobilization of raccoons. Wildlife Society Bulletin 34: 1045–1048. http://dx.doi.org/10.2193/0091-7648(2006)34[1045:EOZFFI]2.0.CO;2CrossRefGoogle Scholar
R Development Core Team 2010 R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing: Vienna, Austria. http://www.R-project.orgGoogle Scholar
Travaini, A and Delibes, M 1994 Immobilization of free-ranging red foxes (Vulpes vulpes) with tiletamine hydrochloride and zolazepam hydrochloride. Journal of Wildlife Diseases 30: 589–591CrossRefGoogle ScholarPubMed
Virtanen, R 1989 Pharmacological profiles of medetomidine and its antagonist, atipamezole. Acta Veterinaria Scandinavica Supplementum 85: 29–37Google ScholarPubMed